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1 Think about… 7.1 The human breathing system 7.2 Gas exchange in the air sacs 7.3 Transport of respiratory gases 7.4 Ventilation Recall ‘Think about…’ Summary concept map 2 3 The answer is… 4 …still a mystery. 5 1 Which parts of our body are in action when we yawn 6 2 Where does the exchange of oxygen and carbon dioxide take place between our body and the atmosphere 7 3 In what forms are oxygen and carbon dioxide carried around our body 8 7.1 The human breathing system gas exchange (氣體交換) O2 CO2 9 7.1 The human breathing system In very small organisms: O2 CO2 • diffuses across cell membrane 10 7.1 The human breathing system In larger organisms: O2 CO2 • cannot diffuse across body surface 11 7.1 The human breathing system In larger organisms: • breathing system (呼吸系統) - for gas exchange • transport system (運送系統) - for carrying gases to body cells 12 7.1 The human breathing system What does the human breathing system consist of? 13 7.1 The human breathing system Human breathing system 3D Model nostril epiglottis bronchiole air sac nasal cavity pharynx larynx trachea bronchus lung 14 7.1 The human breathing system Human breathing system rib diaphragm 15 7.1 The human breathing system Human breathing system intercostal muscle pleural cavity outer pleural membrane inner pleural membrane 16 7.1 The human breathing system air How does air flow into the lungs? 17 7.1 The human breathing system air nasal cavity pharynx larynx trachea 18 7.1 The human breathing system air bronchus bronchiole air sac 19 7.1 The human breathing system 7.1 Examination of the mammalian breathing system 1 Examine the breathing system of a dissected rat or a human torso model. 2 Identify the various structures. 20 7.1 The human breathing system 1 Nostrils and nasal cavity i) Hairs • filter larger dust particles 21 7.1 The human breathing system 1 Nostrils and nasal cavity ii) Mucus-secreting cells traps dust particles & moistens air mucus 22 7.1 The human breathing system 1 Nostrils and nasal cavity iii) Ciliated epithelial cells sweep mucus with dust particles towards pharynx cilia 23 7.1 The human breathing system 1 Nostrils and nasal cavity iv) Capillaries • blood warms up air 24 7.1 The human breathing system 2 Pharynx and larynx pharynx larynx oesophagus trachea 25 7.1 The human breathing system 2 Pharynx and larynx food larynx oesophagus 26 7.1 The human breathing system 2 Pharynx and larynx 1 Tongue pushes food towards pharynx larynx oesophagus 27 7.1 The human breathing system 2 Pharynx and larynx 2 Soft palate moves up, preventing food from entering nasal cavity larynx oesophagus 28 7.1 The human breathing system 2 Pharynx and larynx 3 Larynx rises and epiglottis covers entrance to trachea, preventing choking larynx oesophagus 29 7.1 The human breathing system 2 Pharynx and larynx 30 7.1 The human breathing system 2 Pharynx and larynx epiglottis larynx • made up of cartilage 31 7.1 The human breathing system 2 Pharynx and larynx vocal cords (聲帶) • can vibrate to produce sound 32 7.1 The human breathing system 3 Trachea, bronchi and bronchioles trachea bronchus bronchioles 33 7.1 The human breathing system 3 Trachea, bronchi and bronchioles trachea bronchus bronchioles 34 7.1 The human breathing system 3 Trachea, bronchi and bronchioles lumen C-shaped cartilage • prevents collapse ciliated epithelial cell 35 7.1 The human breathing system 3 Trachea, bronchi and bronchioles Ciliated epithelial cells Trachea Bronchi Bronchiole 36 7.1 The human breathing system 3 Trachea, bronchi and bronchioles Mucus-secreting cells Trachea Bronchi Bronchiole Absent in smaller bronchioles 37 7.1 The human breathing system 3 Trachea, bronchi and bronchioles Capillaries Trachea Bronchi Bronchiole 38 7.1 The human breathing system 3 Trachea, bronchi and bronchioles Cartilage Trachea C-shaped Bronchi Circular Bronchiole Absent 39 7.1 The human breathing system 4 Air sacs • large respiratory surface air sac capillary 40 7.1 The human breathing system 5 Lungs • composed of bronchioles and air sacs • in thoracic cavity (胸腔) 41 7.1 The human breathing system 5 Lungs • protected by rib cage (肋骨籃) vertebral column (脊柱) ribs cartilage sternum (胸骨) 42 7.1 The human breathing system 5 Lungs diaphragm • sheet of muscle intercostal muscles 43 7.1 The human breathing system 5 Lungs 44 7.1 The human breathing system 5 Lungs rib intercostal muscle outer pleural membrane inner pleural membrane right lung pleural cavity 45 7.1 The human breathing system 5 Lungs • pleural cavity filled with pleural fluid (胸腺液) as lubricant (潤滑劑) right lung pleural cavity 46 7.1 The human breathing system 7.2 Examination of the pig lungs 1 Examine the pig lungs. Identify the larynx, epiglottis, trachea, bronchi, left and right lungs. 47 7.1 The human breathing system 7.2 2 The lungs have several lobes. Find out the number of lobes present in the left and the right lungs respectively. 48 7.1 The human breathing system 7.2 3 Feel the hardness of the trachea and the lung tissue with a pair of forceps. 4 Use a water hose to fill the lungs with water through the trachea. Note the changes in the volume of the lungs. 5 Draw a labelled diagram of the lungs. 49 7.1 The human breathing system 1a The human breathing system consists of the respiratory tract and structures that aid breathing. 50 7.1 The human breathing system 1b Air flow along respiratory tract: nostrils nasal cavity pharynx larynx trachea bronchi bronchioles air sacs 51 7.1 The human breathing system 2a In the nostrils, hairs filter larger dust particles. 52 7.1 The human breathing system 2b In the lining of nasal cavity, trachea, bronchi and bronchioles, mucus-secreting cells secrete mucus-secreting cells mucus mucus to moisten the air. 53 7.1 The human breathing system 2c In the lining of nasal cavity, trachea, bronchi and bronchioles, mucus mucus traps the dust particles and bacteria. 54 7.1 The human breathing system 2d In the lining of nasal cavity, trachea, bronchi and bronchioles, blood in the capillaries blood warms the incoming air. 55 7.2 Gas exchange in the air sacs Respiratory gases Oxygen Carbon dioxide 56 7.2 Gas exchange in the air sacs Where does gas exchange take place? 57 7.2 Gas exchange in the air sacs in the air sacs Where does gas exchange take place? 58 7.2 Gas exchange in the air sacs Uptake of oxygen by the blood blood flow capillary air sac 59 7.2 Gas exchange in the air sacs Uptake of oxygen by the blood 1 O2 is inhaled. blood flow O2 60 7.2 Gas exchange in the air sacs Uptake of oxygen by the blood 2 O2 dissolves in water film. blood flow O2 61 7.2 Gas exchange in the air sacs Uptake of oxygen by the blood 3 O2 diffuses into red blood cells. blood flow O2 62 7.2 Gas exchange in the air sacs Removal of carbon dioxide blood flow into the air sacs 1 CO2 diffuses out from capillary. CO2 63 7.2 Gas exchange in the air sacs Removal of carbon dioxide blood flow into the air sacs 2 CO2 diffuses into air sacs. CO2 64 7.2 Gas exchange in the air sacs Removal of carbon dioxide blood flow into the air sacs Animation 3 CO2 is exhaled. CO2 65 7.2 Gas exchange in the air sacs Adaptive features of air sacs 1 Large number of air sacs • provide large surface area for gas exchange 66 7.2 Gas exchange in the air sacs Adaptive features of air sacs 2 Thin wall of air sac • provides short diffusion distance air sac one-cell thick epithelium 67 7.2 Gas exchange in the air sacs Adaptive features of air sacs 3 Water film lining inner surface • keeps inner surface moist to dissolve gases water film 68 7.2 Gas exchange in the air sacs Adaptive features of air sacs 4 Network of capillaries • Rapid transport of gases • Maintain steep air sac concentration gradient capillary red blood cell 69 7.2 Gas exchange in the air sacs 7.3 Examination of the mammalian air sacs 1 Examine the slides or photomicrographs of the mammalian lungs. 70 7.2 Gas exchange in the air sacs 7.3 2 Identify the air sacs. air sac capillary 71 7.2 Gas exchange in the air sacs 7.3 3 Draw a labelled diagram of the air sacs. 72 7.2 Gas exchange in the air sacs 1 How does gas exchange take place in the air sacs? Oxygen concentration in air sacs is higher than that in the capillaries. higher 73 7.2 Gas exchange in the air sacs 1 How does gas exchange take place in the air sacs? Oxygen in incoming air dissolves in the water film lining the air sacs, and then diffuses across the walls of the air sacs and the capillaries into the blood. 74 7.2 Gas exchange in the air sacs 1 How does gas exchange take place in the air sacs? Carbon dioxide concentration in capillaries is higher than that in air sacs. 75 7.2 Gas exchange in the air sacs 1 How does gas exchange take place in the air sacs? Carbon dioxide in blood diffuses capillaries across the walls of the capillaries airsacs sacs into the air in the and the air air sacs. 76 7.2 Gas exchange in the air sacs 2 Adaptive features of the air sacs: Large number largesurface surfacearea area provides a large for gas exchange 77 7.2 Gas exchange in the air sacs 2 Adaptive features of the air sacs: Thin wall provides a short distance for rapid diffusion of gases 78 7.2 Gas exchange in the air sacs 2 Adaptive features of the air sacs: Moist inner surface allows gases to dissolve in the water film for diffusion 79 7.2 Gas exchange in the air sacs 2 Adaptive features of the air sacs: Network of capillaries allows rapid transport of gases to maintain a steep concentration gradient for diffusion 80 7.2 Gas exchange in the air sacs Quick check The film of water on the surface of human air sacs serves to A. B. C. D. Warm the incoming air. Moisten the incoming air. Trap dust in the inhaled air. Dissolve the gases in the inhaled air. 81 7.3 Transport of respiratory gases Oxygen in blood is transported by… 82 7.3 Transport of respiratory gases Oxygen in blood is transported by… red blood cells 83 7.3 Transport of respiratory gases Oxygen is mainly transported by red blood cells 84 7.3 Transport of respiratory gases Adaptive features of red blood cells for carrying oxygen fully packed with haemoglobin (血紅蛋白) oxygen carrier 85 7.3 Transport of respiratory gases Adaptive features of red blood cells for carrying oxygen biconcave disc shape (雙凹圓盤狀): surface area cytoplasmic volume 86 7.3 Transport of respiratory gases Adaptive features of red blood cells for carrying oxygen biconcave disc shape (雙凹圓盤狀): short distance for diffusion 87 7.3 Transport of respiratory gases Adaptive features of red blood cells for carrying oxygen without nucleus: more room for haemoglobin 88 7.3 Transport of respiratory gases Transport of oxygen In lungs air sac O2 red blood cell Hb + O2 → oxyhaemoglobin In body cells 89 7.3 Transport of respiratory gases Transport of oxygen In lungs O2 oxyhaemoglobin → Hb + O2 In body cells 90 7.3 Transport of respiratory gases Transport of oxygen In lungs O2 O2 In body cells 91 7.3 Transport of respiratory gases Transport of carbon dioxide In lungs CO2 In body cells 92 7.3 Transport of respiratory gases Transport of carbon dioxide In lungs hydrogencarbonate ion CO2 + H2O → H+ + HCO3In body cells 93 7.3 Transport of respiratory gases Transport of carbon dioxide In lungs HCO3In body cells 94 7.3 Transport of respiratory gases Transport of carbon dioxide In lungs H+ + HCO3- → H2O + CO2 In body cells 95 7.3 Transport of respiratory gases Transport of carbon dioxide In lungs CO2 In body cells 96 7.3 Transport of respiratory gases 1 Adaptive features of red blood cells for carrying oxygen: Biconcave disc shape surface area area to to • increases surface volume volume ratio 97 7.3 Transport of respiratory gases 1 Adaptive features of red blood cells for carrying oxygen: Biconcave disc shape • shortens diffusion diffusionpath path for oxygen 98 7.3 Transport of respiratory gases 2 Transport of oxygen: In air sacs, oxygen concentration is high . haemoglobin + oxygen oxyhaemoglobin carried by blood 99 7.3 Transport of respiratory gases 2 Transport of oxygen: In body cells, oxygen concentration is low . oxyhaemoglobin haemoglobin + oxygen body cells 100 7.3 Transport of respiratory gases 3 Transport of carbon dioxide: Carbon dioxide is produced by body cells. carbon dioxide + water hydrogencarbonate ions (HCO3-) carried in plasma 101 7.3 Transport of respiratory gases 3 Transport of carbon dioxide: When blood reaches the air sacs, hydrogencarbonate ions carbon dioxide + water air sacs 102 7.4 Ventilation Ventilation (換氣) brought about by Breathing involves Inhalation Exhalation 103 7.4 Ventilation Inhalation Animation 1a Intercostal muscles contract. Rib cage moves upwards and outwards. 104 7.4 Ventilation Inhalation 1b Diaphragm muscles contract. Diaphragm flattens. 105 7.4 Ventilation Inhalation 2 Volume of thoracic cavity increases, pressure decreases. 106 7.4 Ventilation Inhalation 3a Lungs expand. 3b Air pressure in the lungs is lower than atmospheric pressure. 107 7.4 Ventilation Inhalation 4 air Air rushes into lungs. 108 7.4 Ventilation Ventilation (換氣) brought about by Breathing involves Inhalation Exhalation 109 7.4 Ventilation Exhalation 1a Intercostal muscles relax. Rib cage moves downwards and inwards. 110 7.4 Ventilation Exhalation 1b Diaphragm muscles relax. Diaphragm returns to dome shape. 111 7.4 Ventilation Exhalation 2 Volume of thoracic cavity decreases, pressure increases. 112 7.4 Ventilation Exhalation 3a Lungs recoil. 3b Air pressure in the lungs is higher than atmospheric pressure. 113 7.4 Ventilation Exhalation 4 air Air is forced out of the lungs. 114 7.4 Ventilation air pressure in thoracic cavity atmospheric pressure exhalation inhalation exhalation inhalation time 115 7.4 Ventilation respiration = breathing = ventilation 116 7.4 Ventilation Respiration : The chemical process of releasing energy from food. 117 7.4 Ventilation Breathing : The mechanical process of moving air into and out of the breathing system. 118 7.4 Ventilation Ventilation : The movement of air over the respiratory surface to faciliate gas exchange. 119 7.4 Ventilation What is the difference in composition between inhaled and exhaled air? 120 7.4 Ventilation 7.4 Comparison of the composition of inhaled air and exhaled air 1 Collect two jars of inhaled air (atmospheric air) and two jars of exhaled air as shown. 121 7.4 Ventilation 7.4 2 Lower a burning candle quickly into one jar of inhaled air. Close the jar and record how long the candle can burn. Repeat with one jar of exhaled air. 122 7.4 Ventilation 7.4 3 Add 10 cm3 of red hydrogencarbonate indicator into one jar of inhaled air. Close the jar and shake. Note any colour change. Repeat with one jar of exhaled air. 123 7.4 Ventilation 7.4 Results and discussion The results show that exhaled air contains less oxygen but more carbon dioxide than inhaled air. 124 7.4 Ventilation Oxygen Inhaled air 21% Exhaled air 16% Used by body cells Why for respiration different / the same? 125 7.4 Ventilation Carbon dioxide Inhaled air 0.03% Exhaled air 4% Produced by body Why cells during respiration different / the same? 126 7.4 Ventilation Nitrogen Inhaled air 78% Exhaled air 78% Not used or Why produced by body different / the same? cells 127 7.4 Ventilation Water vapour Inhaled air Variable Exhaled air Saturated Moistened by mucus Why and water film different / the same? 128 7.4 Ventilation Other gases Inhaled air Exhaled air 1% 1% 129 7.4 Ventilation Temperature Inhaled air Cooler Exhaled air Warmer Warmed by blood Why different / the same? 130 7.4 Ventilation • Inhaled air consists mainly of oxygen. • Exhaled air consists mainly of carbon dioxide. 131 7.4 Ventilation Both inhaled and exhaled air consists mainly of nitrogen (about 78%). 132 7.4 Ventilation There is more carbon dioxide than oxygen in exhaled air. O2 CO2 133 7.4 Ventilation Exhaled air contains a higher proportion of carbon dioxide when compared with that in inhaled air, its absolute amount (in terms of %) is still lower than that of oxygen. 134 7.4 Ventilation 1 Ventilation involves inhalation and exhalation . It is brought about by ex the movements of the rib cage and the diaphragm . 135 7.4 Ventilation Diaphragm muscles Diaphragm Inhalation Exhalation Contract Relax Flattened Dome shape 136 7.4 Ventilation Intercostal muscles Rib cage Inhalation Exhalation Contract Relax Moves upwards & outwards Moves downwards & inwards 137 7.4 Ventilation Volume of thoracic cavity Lungs Inhalation Exhalation Increases Decreases Inflated Deflated 138 7.4 Ventilation Inhalation Exhalation Lower than Higher than Air pressure atmospheric atmospheric in lungs pressure pressure Direction of air flow Into the lungs Out of the lungs 139 7.4 Ventilation 2 Exhaled air contains more / less O2 than inhaled air. Its CO2 content is higher / lower than that in inhaled air. Exhaled / Inhaled air is saturated with water vapour. 140 1 Which parts of our body are in action when we yawn? Our mouth opens and we breathe in deeply. The abdominal muscles are stretched, the rib cage raises and the diaphragm is pushed down. 141 2 Where does the exchange of oxygen and carbon dioxide take place between our body and the atmosphere? The exchange of oxygen and carbon dioxide takes place in the air sacs. 142 3 In what forms are oxygen and carbon dioxide carried around our body? Oxygen is transported mainly in form of oxyhaemoglobin in red blood cells. Carbon dioxide is transported mainly in form of hydrogencarbonate ions dissolved in plasma. 143 Gas exchange takes place at respiratory surface (air sacs) are parts of human breathing system 144 Gas exchange facilitated by ventilation brought about by breathing 145 breathing involves inhalation exhalation brought about by contraction of intercostal & diaphragm muscles relaxation of intercostal & diaphragm muscles 146 Gas exchange include oxygen transported by involves diffusion of respiratory gases carbon dioxide transported mainly as haemoglobin in hydrogencarbonate red blood cells ions in plasma 147