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The Cardiovascular System Chapters 19, 20, 21 The Closed Circulatory System • Blood is confined to vessels • Heart pumps blood into large vessels that branch into smaller ones leading into the cells • Nutrients & wastes are exchanged by diffusion Three Major Elements: Blood Vessels, Blood, Heart I. Blood Vessels 3 layers: 1. Endothelim - epithelial inner lining (tunica intima) 2. smooth muscle & elastic connective tissue (tunica media) 3. connective tissue covering (tunica externa) Types of blood vessels: Arteries → Arterioles → Capillaries → Venules Arteries: • Carry oxygenated blood away from the heart • Thicker & more elastic walls than veins • Arteries are thicker and more elastic because they are closer to the pumping action of the hear Veins: • Carry deoxygenated blood towards the heart • Less elastic and thinner walls than arteries • Valves prevent backflow of blood • When valves don’t close properly = varicose veins When you walk and your leg muscles squeeze, the venous pump works well. But when you sit or stand, especially for a long time, the blood in your leg veins can pool and the pressure in your veins can increase. If you are a susceptible individual, your veins can stretch if you repeatedly sit or stand for a long time. This stretching can sometimes weaken the walls of your veins and damage your vein valves. Varicose veins may result. Spider veins are mild varicose veins. Capillaries: • Smallest blood vessels found almost near all body cells • Exchange of nutrients, gases & metabolic wastes (through diffusion) • Only one cell thick – contain only tunic intima • Link arteries & veins II. Blood A. Plasma • • • • 55% of blood Liquid portion of the blood 91.5% of plasma = water Also contains dissolved hormones, antibodies, nutrients, wastes, gases Blood Cont. B. Erythrocytes - Red Blood Cells (RBCs) • Formed in the bone marrow • Hemoglobin carries oxygen • Do not have a nucleus and live only about 120 days Blood Cont. C. Leukocytes – White Blood cells (WBCs) • Fight infection and are formed in the bone marrow • Many types Blood Cont. D. Thrombocytes – Platelets • Clot blood by sticking together via protein fibrin