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Respiratory and Urinary Systems Ridding the body of waste products Respiratory System 5/24/2017 Free PowerPoint Template from www.brainybetty.com 3 Respiratory System—Function • To supply oxygen to the blood while removing carbon dioxide from the blood • Filter, warm, and humidify air • Some organs influence speech and smell 5/24/2017 Free PowerPoint Template from www.brainybetty.com 4 Respiratory tracts • Upper tract of respiratory system includes: – Nose, nasal cavity, paranasal sinuses and pharynx • Lower tract of respiratory system includes: – Larynx, trachea, bronchi, lungs and alveoli 5/24/2017 Free PowerPoint Template from www.brainybetty.com 5 Respiratory Organs • Nose –Only externally visible part of the RS –Air enters body through the nares (nostrils) 5/24/2017 Free PowerPoint Template from www.brainybetty.com 6 Nose con’t: • Left and right nasal cavities are separated by the nasal septum • Surface of nasal cavities arehairs warm •Nasal help remove debris andand moist. create a “current” sweeping the debris to the stomach where it is destroyed 5/24/2017 Free PowerPoint Template from www.brainybetty.com 7 Nose con’t: • Olfactory nerve receptors responsible for smell lie in the nasal mucosa • 4 paranasal sinuses drain into the nasal cavities – Frontal, sphenoid, ethmoid and maxillary 5/24/2017 Free PowerPoint Template from www.brainybetty.com 8 Nose con’t: • The sinuses are used to: – Assist with mucus production – Lighten the skull – Provide resonant chambers for sound production 5/24/2017 •2 nasolacrimal ducts (drain tears from eyes) drain into the nose as well. Free PowerPoint Template from www.brainybetty.com 9 Respiratory organs • Pharynx = throat – Muscular passageway ~13cm (5”) long – Air and food use this hallway to get to their proper corridor •Food travels from •Air travels from oropharynx to laryngopharynx to nasopharynx to esophagus oropharynx to laryngopharynx to larynx 5/24/2017 Free PowerPoint Template from www.brainybetty.com 10 Pharynx con’t: • Right and left auditory (Eustachian) tubes open into the pharynx • Masses of lymphatic tissue (tonsils) found here 5/24/2017 •Pharyngeal tonsils (adenoids) found in the upper area of the pharynx Free PowerPoint Template from www.brainybetty.com 11 Respiratory organs • Larynx = Voicebox – Composed of several pieces of hyaline (rigid) cartilage – Epiglottis covers opening of larynx: trapdoor 5/24/2017 •2 fibrous bands (vocal cords) stretch across interior of larynx •Space between vocal cords: glottis Free PowerPoint Template from www.brainybetty.com 12 Respiratory organs • Trachea = Windpipe – ~11cm (4”) long – Lined with ciliated mucosa which beat OPPOSITE of air flow to move debris away from –Smoking inhibits (and eventually lungs destroys) these cilia—debris will enter lungs more frequently and have to be coughed out. (Smoker’s cough) 5/24/2017 Free PowerPoint Template from www.brainybetty.com 13 Respiratory organs • Primary Bronchi – Formed by division of trachea – Branch into right and left lungs • Bronchioles – Smallest conducting passageways for air to travel 5/24/2017 Free PowerPoint Template from www.brainybetty.com 14 Respiratory organs • Alveoli—resemble bunches of grapes – Make up the bulk of the lungs – Walls of each alveolus are composed of a layer of epithelial cells (thinner than a piece of tissue paper) 5/24/2017 Free PowerPoint Template from www.brainybetty.com 15 Alveoli con’t: • External surface of each alveolus is covered with a network of capillaries to enable gas exchange • A surfactant covers each alveolus to prevent it from collapsing as air goes in and out. This surfactant is secreted very shortly before birth, which is why premature babies have breathing issues! 5/24/2017 Free PowerPoint Template from www.brainybetty.com 16 Respiratory organs • Lungs—weigh about 2 ½ # – Occupy entire thoracic cavity except for the most central area – Apex (top) of each lung lies just deep to the clavicle 5/24/2017 Free PowerPoint Template from www.brainybetty.com 17 Lungs con’t: • Base of each lung rests on the diaphragm •Right side has 3 lobes, left side has 2 lobes 5/24/2017 Free PowerPoint Template from www.brainybetty.com 18 Respiratory organs • Pleura –Visceral pleura covers outer surface of lungs and parietal pleura lines inner surfaces of rib cage 5/24/2017 Free PowerPoint Template from www.brainybetty.com 19 Pleura con’t: • Interpleural space normally holds just enough fluid to help make it slippery 5/24/2017 •This slippery surface allows lungs to glide inside the chest cavity Free PowerPoint Template from www.brainybetty.com 20 Pleura con’t: • if air gets in, it will cause additional pressure and lung collapses. 5/24/2017 Free PowerPoint Template from www.brainybetty.com 21 Physiology of Respiration • Respiration is made up of 4 distinct events – Pulmonary ventilation—breathing air into/out of lungs • Inspiration: diaphragm and intercostal muscles contract which opens the thoracic cavity. This causes a vacuum and air rushes into lungs • Expiration: normally a passive process. As the muscles relax, the thoracic cavity becomes smaller so that air is “forced” out of lungs 5/24/2017 Free PowerPoint Template from www.brainybetty.com 22 Physiology con’t: • External respiration—gas exchange between blood and the alveoli via the capillaries surrounding the alveoli (takes place in the lungs) 5/24/2017 Free PowerPoint Template from www.brainybetty.com 23 Physiology con’t: • Respiratory gas exchange (Circulatory system function)— O2/CO2 must be transported to/from the lungs and cells of body • Internal respiration (Circulatory system function)—gas exchange made at the capillaries 5/24/2017 Free PowerPoint Template from www.brainybetty.com 24 Respiratory Definitions • Tidal volume (normal breath)--~500 ml in and out • Vital capacity—largest amount of expelled air in one expiration (~4800 in a normal male) • Inspiratory reserve volume—volume of air forcibly inhaled after inhaling tidal volume 5/24/2017 Free PowerPoint Template from www.brainybetty.com 25 Respiratory Definitions • Expiratory Reserve volume—volume of air forcibly exhaled after expiring tidal volume • Residual volume—air that remains in the lungs and cannot be forced out. This is important so that gas exchange is a continuous process even in between breaths. 5/24/2017 Free PowerPoint Template from www.brainybetty.com 26 Urinary System 5/24/2017 Free PowerPoint Template from www.brainybetty.com 27 Urinary System organs • Kidneys—General Information – Located just above waistline; about the same size as a large bar of soap – Right kidney is a bit lower than the left (crowded by the liver) 5/24/2017 Free PowerPoint Template from www.brainybetty.com 28 Kidneys con’t: • Adipose capsule (heavy cushion of fat) helps keep kidney in place • Renal capsule—fibrous transparent enclosure giving the kidney its shiny appearance 5/24/2017 Free PowerPoint Template from www.brainybetty.com 29 Kidneys con’t: • Kidneys continuously cleanse/monitor blood so it has a rich supply of blood vessels. • ¼ of total blood volume passes through the kidneys every minute of every day! 5/24/2017 Free PowerPoint Template from www.brainybetty.com 30 Kidney—function • Form urine—waste products are filtered from blood and enter nephron. Additional wastes may be secreted into urine as well. • Helps to regulate many substances in the blood 5/24/2017 Free PowerPoint Template from www.brainybetty.com 31 Kidneys con’t: • Internal structure – Renal cortex— outer part of kidney – Renal medulla— inner portion; made up of many triangular regions 5/24/2017 Free PowerPoint Template from www.brainybetty.com 32 Kidney Internal structure con’t: • Medullary pyramids— triangle divisions of medulla •Apex—narrow, innermost end of a pyramid 5/24/2017 Free PowerPoint Template from www.brainybetty.com 33 Kidney Internal structure con’t: • Renal pelvis— expansion of the upper end of the ureter •Calyx—extensions of the pelvis that enclose the tips of the pyramids to collect urine 5/24/2017 Free PowerPoint Template from www.brainybetty.com 34 Kidney con’t: • Nephron— microscopic functional unit of the kidney – More than one million per kidney – Look like tiny funnels 5/24/2017 Free PowerPoint Template from www.brainybetty.com 35 Kidney con’t: • Nephrons are composed of a glomerulus (knot of capillaries) and a renal tubule •At the end of the renal tubule is a cuplike structure called the Bowman’s capsule that surrounds the glomerulus 5/24/2017 Free PowerPoint Template from www.brainybetty.com 36 Formation of Urine • Combination of three processes: –Filtering –Reabsorption –Secretion 5/24/2017 Free PowerPoint Template from www.brainybetty.com 37 Formation of Urine • Filtration—continuous process in each glomerulus –125ml/min = 180 L fluid filtered by kidneys each day…no one voids that much! –Most of the filtered substances are reabsorbed into the body. 5/24/2017 Free PowerPoint Template from www.brainybetty.com 38 Formation of Urine • Reabsorption –~178 L/day of liquid is reabsorbed into body –Glucose (usually) , amino acids, etc—anything the body needs will usually be reabsorbed. –Sodium reabsorption rates vary— depending on amount in body 5/24/2017 Free PowerPoint Template from www.brainybetty.com 39 Reabsorption con’t: • Nitrogenous wastes are not reabsorbed – Urea—formed by liver as end product of protein breakdown when amino acids are used as energy – Uric acid—when nucleic acids are broken down – Creatine—generally associated with physiology of muscles 5/24/2017 Free PowerPoint Template from www.brainybetty.com 40 Formation of Urine • Secretion –H+, K+, and drugs are deposited into urine 5/24/2017 Free PowerPoint Template from www.brainybetty.com 41 Characteristics of Urine • Freshly voided urine is generally clear (not cloudy) • Pale to deep yellow in color –Yellow color from urochrome—a pigment that results from breakdown of hemoglobin • Urine is sterile 5/24/2017 Free PowerPoint Template from www.brainybetty.com 42 Characteristics of Urine • There is a slight aromatic odor in fresh urine (not unpleasant). If allowed to stand, urine takes on the ammonia smell due to the action of bacteria on urine solutes. • If addition, some drugs, foods, and various diseases can alter the smell of urine • pH = ~6 5/24/2017 Free PowerPoint Template from www.brainybetty.com 43 Urinary System Organs • Ureters – Tubes carrying urine from collecting tubules into bladder – ~6mm wide and 25 – 30cm (1012”) long 5/24/2017 –Peristalsis encourages urine down to bladder Free PowerPoint Template from www.brainybetty.com 44 Urinary System Organs • Bladder – Location • Empty, just behind pubic symphysis • Full, projects upward into lower portion of abdominal cavity 5/24/2017 Function Elastic fibers and involuntary muscle in wall of bladder make it suitable to contract and expand as needed to hold urine. Free PowerPoint Template from www.brainybetty.com 45 Urinary System Organs • Urethra – Carries urine from bladder to outside of the body – Opening is called the urinary meatus – 4cm (1 1/2”) long in females; 20cm (8”) long in males 5/24/2017 Free PowerPoint Template from www.brainybetty.com 46 Micturition • Another name for urination/voiding • 2 sphincters (internal urethral/external urethral) close passageway of urethra to allow bladder to fill • Usually void at 350ml; urge can begin at 150ml. • Reflex contractions of internal sphincter will stop after about 1 minute. You will eventually void whether you want to or not. 5/24/2017 Free PowerPoint Template from www.brainybetty.com 47 Pathologies Disorders • SIDS—Sudden Infant Death Syndrome – Infants in seemingly good health die in their sleep. Some cases are attributed to breathing mechanisms not functioning correctly, others of heart abnormalities. Most cases of unexplained infant death get listed as SIDS 5/24/2017 Free PowerPoint Template from www.brainybetty.com 49 Disorders • Cystic Fibrosis – Most common lethal genetic disease – Oversecretion of mucus that clogs the respiratory –Affects other systems passages putting as well—digestive person (usually a system (clogs ducts that child) at risk for deliver pancreatic fatal infections enzymes and bile to SI) 5/24/2017 Free PowerPoint Template from www.brainybetty.com 50 Disorders • Emphysema— condition where the alveoli enlarge; this chronic inflammation leads to fibrosis of the lungs. 5/24/2017 •Fibrosis makes the lungs less elastic so people have to force air in AND OUT of the lungs…leaving them exhausted. •Usually caused by smoking Free PowerPoint Template from www.brainybetty.com 51 Disorders • Pneumonia—lung infection that can be caused by bacteria, viruses, fungi or parasites. – Most commonly caused by viruses. • Bronchitis—mucosa of the lower respiratory passages are severely inflamed and producing excessive amounts of mucus. This excess mucus impairs ventilation and gas exchange. 5/24/2017 Free PowerPoint Template from www.brainybetty.com 52 Disorders • Sinusitis—infection of the sinuses • Sinus headache—passages from the sinuses to nose are blocked causing a partial vacuum and a localized headache in the sinuses occurs. 5/24/2017 Free PowerPoint Template from www.brainybetty.com 53 Disorders • Asthma—caused by chronically inflamed, hypersensitive bronchial passages that respond to many irritants with coughing, wheezing, and impaired respiration. • Pleurisy—inflammation of the pleura 5/24/2017 Free PowerPoint Template from www.brainybetty.com 54 Urinary Disorders • Ptosis—amount of fatty tissue surrounding kidneys declines to such an extent that the kidneys drop—can cause ureters to kink • Oliguria—abnormally low urine output (100 – 400ml/day). Usually indicates a problem with the kidneys’ ability to filter wastes • Anuria—less than 100ml of urine produced per day 5/24/2017 Free PowerPoint Template from www.brainybetty.com 55 Urinary Disorders • Polyuria—an excess of 2.5L of urine produced a day. • Incontinence—voiding involuntarily • UTI—Urinary Tract Infection –Any infection of any portion of the kidneys, ureters, bladder or urethra. 5/24/2017 Free PowerPoint Template from www.brainybetty.com 56 Urinary Disorders • Renal calculi—kidney stones – Concentrated urine solutes in the kidneys form crystalline “stones” that they have to pass through the ureters and out the urethra. The ureters are much narrower than the urethra, so the passage from kidney to bladder is the most agonizing • Renal colic—pain caused by passing kidney stone 5/24/2017 Free PowerPoint Template from www.brainybetty.com 57 Urinary Disorders 5/24/2017 Free PowerPoint Template from www.brainybetty.com 58