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Chapter 18: Practical Applications of Immunology
Vaccination
Vaccines
Diagnostic
Tests
ELISA
Therapeutic
Immunity
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FINAL ROUND
© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$100 Question
The term vaccination was coined to honor the
work of
a. Alexander Fleming.
b. Louis Pasteur.
c. Edward Jenner.
d. Robert Koch.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$100 Answer
The term vaccination was coined to honor the
work of
a. Alexander Fleming.
b. Louis Pasteur.
c. Edward Jenner.
d. Robert Koch.
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© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$200 Question
Vaccination is frequently the ONLY feasible
method of controlling diseases caused by
a. fungi.
b. bacteria.
c. viruses.
d. protozoa.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$200 Answer
Vaccination is frequently the ONLY feasible
method of controlling diseases caused by
a. fungi.
b. bacteria.
c. viruses.
d. protozoa.
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© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$300 Question
When most of the population is immune, the
population is said to possess _____ immunity.
a. herd
b. innate
c. population
d. natural
ANSWER
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© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$300 Answer
When most of the population is immune, the
population is said to possess _____ immunity.
a. herd
b. innate
c. population
d. natural
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© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$400 Question
Which of the following diseases can be controlled
by behavioral and environmental methods?
a. cholera
b. measles
c. rubella
d. chickenpox
ANSWER
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© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$400 Answer
Which of the following diseases can be controlled
by behavioral and environmental methods?
a. cholera
b. measles
c. rubella
d. chickenpox
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© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$500 Question
Which vaccine is administered as two doses at
least 6 months apart in children?
a. MMR vaccine
b. polio vaccine
c. hepatitis A vaccine
d. Hib vaccine
ANSWER
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© 2013 Pearson Education, Inc.
Topic 1: Vaccination
$500 Answer
Which vaccine is administered as two doses at
least 6 months apart in children?
a. MMR vaccine
b. polio vaccine
c. hepatitis A vaccine
d. Hib vaccine
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© 2013 Pearson Education, Inc.
Topic 2: Vaccines
$100 Question
Which vaccines more closely mimic an actual
infection?
a. attenuated whole-agent
b. inactivated whole-agent
c. subunit
d. conjugated
ANSWER
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© 2013 Pearson Education, Inc.
Topic 2: Vaccines
$100 Answer
Which vaccines more closely mimic an actual
infection?
a. attenuated whole-agent
b. inactivated whole-agent
c. subunit
d. conjugated
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Topic 2: Vaccines
$200 Question
The Salk polio vaccine is an example of a(n)
a. inactivated whole-agent vaccine.
b. toxoid.
c. attenuated whole-agent vaccine.
d. acellular vaccine.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 2: Vaccines
$200 Answer
The Salk polio vaccine is an example of a(n)
a. inactivated whole-agent vaccine.
b. toxoid.
c. attenuated whole-agent vaccine.
d. acellular vaccine.
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© 2013 Pearson Education, Inc.
Topic 2: Vaccines
$300 Question
Which of the following vaccines uses ONLY the
antigenic fragments of a microorganism that best
stimulate an immune response?
a. nucleic acid vaccines
b. conjugated vaccines
c. subunit vaccines
d. inactivated killed vaccines
ANSWER
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© 2013 Pearson Education, Inc.
Topic 2: Vaccines
$300 Answer
Which of the following vaccines uses ONLY the
antigenic fragments of a microorganism that best
stimulate an immune response?
a. nucleic acid vaccines
b. conjugated vaccines
c. subunit vaccines
d. inactivated killed vaccines
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© 2013 Pearson Education, Inc.
Topic 2: Vaccines
$400 Question
The development of cell culture techniques was
very important in the development of vaccines for
diseases caused by
a. protozoa.
b. fungi.
c. bacteria.
d. viruses.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 2: Vaccines
$400 Answer
The development of cell culture techniques was
very important in the development of vaccines for
diseases caused by
a. protozoa.
b. fungi.
c. bacteria.
d. viruses.
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© 2013 Pearson Education, Inc.
Topic 2: Vaccines
$500 Question
Which of the following has been added to vaccines
to increase the effectiveness of antigens?
a. adjuvants
b. formalin
c. phenol
d. polysaccharides
ANSWER
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© 2013 Pearson Education, Inc.
Topic 2: Vaccines
$500 Answer
Which of the following has been added to vaccines
to increase the effectiveness of antigens?
a. adjuvants
b. formalin
c. phenol
d. polysaccharides
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© 2013 Pearson Education, Inc.
Topic 3: Diagnostic Tests
$100 Question
Antibody molecules that are produced by a single
hybridoma clone are called
a. human antibodies.
b. monoclonal antibodies.
c. hybrid cells.
d. identical antibodies.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 3: Diagnostic Tests
$100 Answer
Antibody molecules that are produced by a single
hybridoma clone are called
a. human antibodies.
b. monoclonal antibodies.
c. hybrid cells.
d. identical antibodies.
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© 2013 Pearson Education, Inc.
Topic 3: Diagnostic Tests
$200 Question
Which test involves the reaction of soluble
antigens with IgG or IgM antibodies to form
lattices?
a. precipitin ring test
b. direct agglutination test
c. indirect agglutination test
d. viral hemagglutination inhibition test
ANSWER
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© 2013 Pearson Education, Inc.
Topic 3: Diagnostic Tests
$200 Answer
Which test involves the reaction of soluble
antigens with IgG or IgM antibodies to form
lattices?
a. precipitin ring test
b. direct agglutination test
c. indirect agglutination test
d. viral hemagglutination inhibition test
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© 2013 Pearson Education, Inc.
Topic 3: Diagnostic Tests
$300 Question
An antigen–antibody reaction in which specific
antibodies block the harmful effects of a bacterial
exotoxin or a virus is a(n) _____ reaction.
a. neutralization
b. precipitation
c. direct agglutination
d. indirect agglutination
ANSWER
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Topic 3: Diagnostic Tests
$300 Answer
An antigen–antibody reaction in which specific
antibodies block the harmful effects of a bacterial
exotoxin or a virus is a(n) _____ reaction.
a. neutralization
b. precipitation
c. direct agglutination
d. indirect agglutination
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© 2013 Pearson Education, Inc.
Topic 3: Diagnostic Tests
$400 Question
Immunoelectrophoresis is an essential part of
a. the Western blot test.
b. seroconversion.
c. the precipitin ring test.
d. the direct agglutination test.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 3: Diagnostic Tests
$400 Answer
Immunoelectrophoresis is an essential part of
a. the Western blot test.
b. seroconversion.
c. the precipitin ring test.
d. the direct agglutination test.
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Topic 3: Diagnostic Tests
$500 Question
What tests are commonly used for the rapid
detection of serum antibodies against many
bacterial and viral diseases?
a. direct agglutination
b. immunodiffusion
c. latex agglutination
d. viral hemagglutination inhibition
ANSWER
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© 2013 Pearson Education, Inc.
Topic 3: Diagnostic Tests
$500 Answer
What tests are commonly used for the rapid
detection of serum antibodies against many
bacterial and viral diseases?
a. direct agglutination
b. immunodiffusion
c. latex agglutination
d. viral hemagglutination inhibition
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Topic 4: ELISA
$100 Question
The ELISA procedures are very popular
because they
a. are inexpensive.
b. are easy to perform.
c. require little interpretive skill to read.
d. test for many diseases.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 4: ELISA
$100 Answer
The ELISA procedures are very popular
because they
a. are inexpensive.
b. are easy to perform.
c. require little interpretive skill to read.
d. test for many diseases.
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© 2013 Pearson Education, Inc.
Topic 4: ELISA
$200 Question
The indirect ELISA test differs from the direct
ELISA test in that it detects
a. antigens.
b. antibodies.
c. enzymes.
d. toxins.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 4: ELISA
$200 Answer
The indirect ELISA test differs from the direct
ELISA test in that it detects
a. antigens.
b. antibodies.
c. enzymes.
d. toxins.
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Topic 4: ELISA
$300 Question
What is adsorbed to the well on the microtiter
plate in a direct ELISA?
a. antibodies
b. cells
c. antigens
d. enzymes
ANSWER
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Topic 4: ELISA
$300 Answer
What is adsorbed to the well on the microtiter
plate in a direct ELISA?
a. antibodies
b. cells
c. antigens
d. enzymes
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© 2013 Pearson Education, Inc.
Topic 4: ELISA
$400 Question
In the indirect ELISA test, the microtiter well
contains a(n)
a. antibody
b. enzyme.
c. antigen.
d. substrate.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 4: ELISA
$400 Answer
In the indirect ELISA test, the microtiter well
contains a(n)
a. antibody
b. enzyme.
c. antigen.
d. substrate.
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Topic 4: ELISA
$500 Question
In a direct ELISA, which of the following does the
patient provide?
a. antigen
b. antibodies
c. substrate
d. enzymes
ANSWER
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© 2013 Pearson Education, Inc.
Topic 4: ELISA
$500 Answer
In a direct ELISA, which of the following does the
patient provide?
a. antigen
b. antibodies
c. substrate
d. enzymes
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Topic 5: Therapeutic Immunity
$100 Question
Diagnostic immunology was revolutionized by the
introduction of
a. Western blotting.
b. the ELISA test.
c. complement fixation.
d. monoclonal antibodies.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 5: Therapeutic Immunity
$100 Answer
Diagnostic immunology was revolutionized by the
introduction of
a. Western blotting.
b. the ELISA test.
c. complement fixation.
d. monoclonal antibodies.
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© 2013 Pearson Education, Inc.
Topic 5: Therapeutic Immunity
$200 Question
Which of the following tests has declined in use?
a. complement-fixation tests
b. precipitin ring test
c. immunoelectrophoresis
d. fluorescent-antibody tests
ANSWER
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© 2013 Pearson Education, Inc.
Topic 5: Therapeutic Immunity
$200 Answer
Which of the following tests has declined in use?
a. complement-fixation tests
b. precipitin ring test
c. immunoelectrophoresis
d. fluorescent-antibody tests
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© 2013 Pearson Education, Inc.
Topic 5: Therapeutic Immunity
$300 Question
Which of the following is a therapeutic application
of monoclonal antibodies?
a. identifying breast cancer
b. treating Hodgkin’s lymphoma
c. testing for drugs in urine
d. diagnosing HIV infection
ANSWER
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© 2013 Pearson Education, Inc.
Topic 5: Therapeutic Immunity
$300 Answer
Which of the following is a therapeutic application
of monoclonal antibodies?
a. identifying breast cancer
b. treating Hodgkin’s lymphoma
c. testing for drugs in urine
d. diagnosing HIV infection
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Topic 5: Therapeutic Immunity
$400 Question
Which of the following is a nonimmunological
test?
a. ELISA
b. PCR
c. Western blot
d. FACS
ANSWER
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© 2013 Pearson Education, Inc.
Topic 5: Therapeutic Immunity
$400 Answer
Which of the following is a nonimmunological
test?
a. ELISA
b. PCR
c. Western blot
d. FACS
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© 2013 Pearson Education, Inc.
Topic 5: Therapeutic Immunity
$500 Question
Most newer tests
a. are less sensitive.
b. require more judgment to read.
c. require less highly trained personnel.
d. are more time consuming.
ANSWER
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© 2013 Pearson Education, Inc.
Topic 5: Therapeutic Immunity
$500 Answer
Most newer tests
a. are less sensitive.
b. require more judgment to read.
c. require less highly trained personnel.
d. are more time consuming.
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© 2013 Pearson Education, Inc.
FINAL ROUND Question
A patient’s blood did NOT have any antibody titer
before an illness but has a significant titer while the
disease is progressing. This phenomenon, which
occurs in HIV infections, is called
a. variolation.
b. attenuation.
c. seroconversion.
d. agglutination.
ANSWER
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© 2013 Pearson Education, Inc.
FINAL ROUND Answer
A patient’s blood did NOT have any antibody titer
before an illness but has a significant titer while the
disease is progressing. This phenomenon, which
occurs in HIV infections, is called
a. variolation.
b. attenuation.
c. seroconversion.
d. agglutination.
BACK TO GAME
© 2013 Pearson Education, Inc.