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Mitosis 5.2 I. Purpose To grow more cells Example: Growing taller, growing roots To reproduce asexually Example: Hydra buds to reproduce Repair damaged tissue Example: A tear in skin –cells multiply to repair the tissue. II. Overview Mitosis – the division of the eukaryotic cell’s nucleus Cells divide into 2 daughter cells Daughter cells are identical to parent cells Each receives an exact copy of the chromosomes present in the parent cell Done in somatic cells - typical body cells II. Overview Chromosome – coiled structures made of DNA and proteins; consists of two identical copies linked together (sister chromatids) Gene – organized chromosomal units that contain the instructions for a single protein II. Overview There are 4 stages of mitosis: 1. Prophase 2. Metaphase 3. Anaphase 4. Telophase / Cytokinesis The rest of the cell’s life is spent in interphase. IPMAT!! III. Stage #1- Prophase Chromatin in the nucleus coils and becomes distinct chromosomes. Chromosomes that were duplicated during the “S” phase join with their sister chromatid. Join at the centromere III. Stage #1 - Prophase A mitotic spindle grows out from centrioles in the cytoplasm. The nuclear envelope disappears. Spindle attaches to the centromere (kineticore) and pulls the chromosomes to the center. III. Stage #1 - Prophase IV. Stage #2 - Metaphase Centrioles are positioned at the poles. The chromosomes are lined up in the middle the metaphase plate. EQUATOR = MIDDLE Metaphase = Meet (in the Middle) IV. Stage #2 - Metaphase The sister chromatids are lined up on either side of the plate The spindle is attached to each chromatid and prepares for separation. V. Stage #3 - Anaphase The spindle fibers “reel” in the chromatids. The poles move farther apart. V. Stage #3 - Anaphase The microtubules which make up the spindle get shorter, pulling the chromatids toward the poles. Anaphase = Away VI. Stage #4 - Telophase A nucleus begins to reform in the new cell. Chromosomes lengthen into chromatin. Mitotic spindle disappears. Telophase = Terminal = End VI. Stage #4 - Telophase A cleavage furrow appears, separating the two cells. Checkpoint ! Cytokinesis pinches the cell into two separate cells. VII. Cytokinesis Division of cytoplasm Animal cells cell membrane pinches together until the cell membrane separates forming 2 daughter cells Plant cells relatively rigid; a cell plate formed in the middle of the dividing cell from membrane vesicles VIII. Plant Cell Cytokinesis Plant cells form a plate between the two new cells that later becomes a cell wall. Stages of Mitosis Stages of Mitosis Stages of Mitosis Quick Review of Mitosis Online Activity Exploring Life Online Activity 2 Help Remembering Cell Division *IPMAT* Intelligent People Meet At Three I Picked My Apple Tree