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Chapter 12 The Cell Cycle Rudolf Virchow-1855 “Omnis cellula e cellula” Every cell from a cell. In this chapter we will learn how cells reproduce to form genetically equivalent daughter cells. Roles of Cell Division Genome Chromosomes Chromosomes Chromosomes - Structure Centromere Goal of cell division Cell Cycle - parts 1. Interphase Interphase - parts G1 S G2 Mitotic Phase - parts Mitosis - Purpose Mitosis Steps Prophase Prophase Prometaphase Prometaphase Metaphase Metaphase Anaphase Anaphase Kinetochores Kinetochores Telophase Telophase Cytokinesis Cytokinesis - Animal Cytokinesis - Plants Cell Plate Cell Division Animal Cell - Mitosis Plant Cell - Mitosis Evolution of Mitosis Regulation of Cell Division Checkpoints G1 Checkpoint GO Go Phase Protein Kinase Checkpoint - G2 MPF Active MPF has: CDK Cyclin Active MPF Growth Factors PDGF Density-Dependent Inhibition Density-Dependent Inhibition Anchorage Dependence Cancer Cells Comment Summary Know the phases and steps of the cell cycle. Be able to discuss the “regulation” of the cell cycle.
