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Vertigo Prof. Dr. Jihad K. Albaba Definitions Of Vertigo. Illusion of motion. Hallucination of motion. Patient feels as if he is turning in stationary environment or objects around him moving. Dizziness (Loss Of Balance) Is a group of sensations as feeling of : Light headedness. Unsteadiness. Confusion. Faintness. All are of vascular origin or psychoneurotic. Human balance system Vestibular system. Proprioceptive receptors: Light touch in skin. Stretch receptors of muscle spindle. Eye. The three systems are intermingled in the CNS. Vestibular labyrinth Causes of Vertigo Non-labyrinthine Non-labyrinthine: Cardiovascular causes Metabolic causes Vascular insufficiency Intracranial tumours Intracranial haemorrhage Multiple sclerosis CAUSES of CENTRAL Labyrinthine VERTIGO Cerebellopontine angle tumors (majority are acoustic neuromas) Vertebral-basilar circulation vascular events Vestibular nuclei area TIA or stroke Cerebellar infarction or hemorrhage Lateral medullary infarct (Wallenberg’s syndrome) Multiple sclerosis Complex partial seizures (temporal lobe epilepsy) Migraine with vertiginous symptoms Post traumatic brainstem injury (Postconcussive syndrome) Infections (meningitis, encephalitis Causes of Peripheral Vertigo (Labyrinthine Vertigo) 1.BPPV 2. Meniere’s Disease 3. Vestibular Neuronitis (viral labyrinthitis) 4. Otitis Media 5. Vestibular migraine 6. ‘Senile’ vestibulopathy Rare Causes • Acoustic neuroma • Vertebro-basilar insufficiency • Otosclerosis • Perilymph fistula • Ototoxic drugs • Temporal bone fracture • Syphilis • Others Causes of Peripheral Vertigo Toxic chemicals Qunidine Alcohol Cisplatin Aminoglycosides Aspirin Chloramphenicol Phenytoin Minocycline Furosemide Quinine Ethacrynic acid BPPV • Common • Easily diagnosed • Easily treated • Patients can be Cured of their condition • Precipitated by head position • Vertigo lasts for seconds • Multiple brief attacks typical • Spontaneous remission, but may recur Short – lived episodic rotatory vertigo Benign proxysmal positional vertigo. Labyrithine fistula. Caloric effect. Alternobaric vertigo. Post- concussional syndrome. Vertebrobasilar insufficiency. Cervical vertigo. Comparison between peripheral & central Vertigo: BPPV CNS Latent period A few seconds Nil Distress Present:may be severe with patient clutching at couch or examiner Nil Direction of nystagmus This is usually rotatory and is anticlockwise with the right ear down and clockwise with the left ear down.(when the nystagmus is horizontal it is towards the undermost ear) Variable Duration of nystagmus Less than 30 second Persists while position maintained On sitting up again Similar events with nystagmus in opposite direction. Nystagmus stops fatiguability Nystagmus and dizziness stop with repeated testing. Nystagmus persists with repeated testing Characteristics of Peripheral and Central Vertigo Peripheral Central Intensity Moderate to Intense Mild to Moderate Temporal Pattern Brief, episodic Chronic, continuous Onset Abrupt Gradual Nystagmus Rotatory / Horizontal Any kind including bizarre / vertical. Nausea / Vomiting Common Uncommon Hearing loss Possible Unlikely Neurological Deficits Otherwise none Often present Nystagmus: Defined as involuntary, rhythmical, oscillatory movements of the eye. And its always due to abnormal maintenance of eye posture. Physiological Nystagmus. Pathological Nystagmus. Pathological Nystagmus. Ocular Vestibular Brainstem Cerebellar Toxic •Rotatory •Horizontal •Bi-directional • Rebound •Convergent Physiological Nystagmus. Seen in normal person when focusing on a series of fast-moving objects at a sufficiently close distance, as in ‘railway nystagmus’. Vestibular Nystagmus Horizontorotatory. Has slow component (Labyrinthine). Rapid component. Suppressed by optic fixation. Examination of patient History – Trauma, Drugs Ears Examination- hearing ,DM ,BP, Renal, Infection. Neurology – Gait, Memory , Voice, Cranial Nerves, Hearing , Muscle Tone, Cerebellum. , Infection , trauma, Surgery. Cardio Vascular SystemBP Standing & laying – Pulse Regularity & Bilateral equality. Meniere’s Disease • Pathology: ‘endolymphatic hydrops’ • Need 4 symptoms for classical meniere’s: Aural fullness Vertigo lasting minutes to hours Tinnitus Hearing loss • Symptoms remit and recur • 85% unilateral • Complete remission in 60% To Make Diagnosis of Meniere’s • Typical history • Examination: may be spontaneous nystagmus, Hallpike test negative • Investigations: 1. Audiogram- low frequency SNHL 2. ECog- endolymphatic hydrops 3. Caloric testing- hypoactive labyrinth 4. MRI – to exclude acoustic neuroma Treatment of Meniere’s Disease • Medical: Low salt diet 2. Vestibular Suppressants 3. Vasodilators 4. Diuretics 1. 1. Surgical: Intratympanic gentamicin 2. Endolymphatic sac procedure 3. VNS 4. Labyrinthectomy Meniere’s Variants • Cochlear MD • Vestibular MD • Lermoyez Syndrome Have aural fullness as common denominator Vestibular Neuronitis • ‘Viral labyrinthitis’ • Prodrome- non-specific viral illness • Vertigo with nausea and vomiting • Vertigo lasts days to weeks • No hearing loss • Diagnosis made on typical history • Treatment with vestibular suppressants Otitis Media • Serous or suppurative OM • Serous OM restricts RW membrane, or there may be serous labyrinthitis • Improvement with drainage • Suppurative OM – reversible serous labyrinthitis or irreversible suppurative labyrinthitis Vertigo with Migraine • Vestibular migraine, or vertebro-basilar migraine • Impairment of circulation to vestibular nuclei. • Vasoconstriction causes- vertigo, dysarthria, ataxia, paraesthesia, visual. • Vasodilation causes headache, which may not always be present. • Treatment with migraine prophylactics ‘Senile Vestibulopathy’ • Diagnosis of exclusion • Old patient with ‘dizziness’ • Combination of cervical spondylosis, V-B insufficiency, vestibular degeneration, poor vision, deteriorating mobility • Exclude BPPV Vertigo investigations Blood. X-ray. Audiology. ENG. EEG. Prof. Dr. Jihad K. Albaba Treatment of vertigo Treatment of Acute Case (e.g. bed rest, fluids, drugs). Treatment of Possible Cause (e.g. Rehabilitation) . Rehabilitation & Follow up. Surgical Treatment. Prof. Dr. Jihad K. Albaba Thank You