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A STUDY OF TREATMENT DURATION USING THE DISCREPANCY INDEX Bradley G. Simister, D.D.S. An Abstract Presented to the Faculty of the Graduate School of Saint Louis University in Partial Fulfillment of Requirements for The Degree of Master of Science in Dentistry 2007 ABSTRACT A constant question in any orthodontic office is “When do I get my braces off?” A better understanding of those factors that influence treatment duration would be a great benefit for both the patient and the doctor. The purpose of this retrospective study was to look at the influence of pretreatment malocclusion on treatment duration. The severity of malocclusion was defined by the American Board of Orthodontics’ Discrepancy Index. Data were gathered from one orthodontic office on 98 patients treated with comprehensive orthodontics. The patient sample was collected so as to eliminate, to the greatest degree possible, the variability of patient cooperation. The DI measurements were used to collect pretreatment information and relate it to treatment duration. time was 22.1 months. The average treatment Six of the fourteen pretreatment variables were found to be significant in contributing to treatment variability: Class II malocclusion, buccal posterior crossbite, palatal impingement, total DI score, ANB angle, and overjet. Quality of the finished cases was not evaluated. 1 A STUDY OF TREATMENT DURATION USING THE DISCREPANCY INDEX Bradley G. Simister, D.D.S. A Thesis Presented to the Faculty of the Graduate School of Saint Louis University in Partial Fulfillment of Requirements for The Degree of Master of Science in Dentistry 2007 COMMITTEE IN CHARGE OF CANDIDCACY Clinical Professor Sheldon Rosenstein Chairperson and Advisor Assistant Professor Maria Atique Assistant Professor Heidi Isreal i ACKNOWLEDGEMENTS I would like to thank all the members of my committee for their time and effort. encouragement. I appreciate their guidance and I would also like to thank the orthodontist who so graciously made his office available to me. A special thanks to his staff for their kindness and generosity in helping me with the data collection. you all. ii Thank DEDICATION I would like to dedicate this work to my wife and children. This was the culmination of eight years in school together. Sondra thank you for your endless patience and love. I love you all. iii TABLE OF CONTENTS List of Tables...........................................v List of Figures..........................................vi CHAPTER 1: INTRODUCTION..................................1 CHAPTER 2: REVIEW OF THE LITERATURE......................3 Socioeconomic Factors..........................3 Age......................................3 Gender...................................4 Socioeconomic status.....................5 Treatment Method...............................5 Extraction vs. Non extraction............5 One Phase vs. Two Phase..................6 Detail and Finish........................7 Patient Cooperation............................8 Oral Hygiene.............................8 Broken Appointments/Appliances...........8 Elastics/Headgear Compliance.............9 Malocclusion Characteristics..................10 Dental..................................10 Skeletal Discrepancies..................11 Discrepancy Index.............................11 History.................................11 References....................................19 CHAPTER 3: JOURNAL ARTICLE..............................22 Abstract......................................22 Introduction..................................23 Materials and Methods.........................25 Results.......................................28 Discussion....................................31 Conclusions...................................32 Literature Cited..............................34 Appendix ..............................................36 Vita Auctoris...........................................41 iv LIST OF TABLES Table I: Mean Values of Study Sample with Similarities and Differences for Malocclusion Classification (N=98)..........................36 Table II: Correlation of Continuous Variables of Class I and Class II Patients with Treatment Time (N=98)...................................36 Table III: Correlation of Categorical Variables of Class I and Class II Patients with Treatment Time (N=98)........................37 Table IV: Total Treatment Time and Other Discriminating Variables Found in an Analysis of Variance for Occlusal Classification Defined by 3 Groups (Class I, Mild Class II, Class II)...37 Table V: Tukey HSD Post Hoc Test Differences Found Between Class II and Other Classifications Of Variables in the Analysis of Variance (Class I, Mild Class II, Class II).............38 v LIST OF FIGURES Figure 1: Overjet Measurement...........................12 Figure 2: Overbite Measurement..........................13 Figure 3: Anterior Openbite Measurement.................13 Figure 4: Lateral Openbite Measurement..................14 Figure 5: Crowding......................................14 Figure 6: Occlusion.....................................15 Figure 7: Lingual Posterior Crossbite...................15 Figure 8: Buccal Posterior Crossbite....................16 Figure 9: Cephalometric Measurements....................17 Figure 10A: Receiver Operator Curve of Class II Malocclusion and Treatment Time.............39 Figure 11A: Receiver Operator Curve for the Dichotomized DI (>15) and Treatment Time.................40 vi CHAPTER 1: INTRODUCTION A constant question in any orthodontic office is “When do I get my braces off?” A better understanding of those factors that influence treatment duration would therefore be of great benefit for both patient and doctor. Patients are anxious to be finished with the braces and observe the outcome of their investment. Treatment time in braces can have an impact on family, missed school, work, and finances. The orthodontist in turn would have a more efficient office; patients are more likely to be happy when appliances are removed in a timely manner. Numerous studies have looked at factors involved in treatment duration in an attempt to explain variability. Some factors have been consistently documented while others have had mixed results. The use of an occlusal index is one way to study and quantify a malocclusion and subsequently there have been a number of different indices developed. The American Board of Orthodontics has in recent years developed an index for the purpose of evaluating case selection to be presented to the board for certification, the Discrepancy Index (DI). The goal of this index was not to assess treatment need but treatment complexity. 1 The purpose of this retrospective study was to look at the influence of the pretreatment malocclusion, as defined by the American Board of Orthodontics’ (ABO) Discrepancy Index (DI), on treatment duration. 2 CHAPTER 2: REVIEW OF THE LITERATURE Factors that influence the duration of orthodontic treatment can be divided into four broad categories: socioeconomic characteristics, treatment method, patient cooperation, and malocclusion characteristics.1 Many studies have looked at these various categories and their impact on the duration of treatment. Socioeconomic Factors Socioeconomic factors that influence treatment duration include age, gender, and socioeconomic status.2-4 Age The age of a patient has been cited as a factor in treatment time. Weiss and Eiser noted that age is a significant factor, but it was due to the fact that children under the age of 12 are much more likely to cooperate.5 Poor cooperation has been consistently shown to be of great significance in increasing treatment duration.1,6-10 Adolescents with significant growth remaining can contribute to reduction of treatment time, and this is particularly true for the Class II patient where growth can significantly modify the treatment outcome.11 3 Others have reported that age did not play a key role in treatment duration.6,7,10,12 Gianelly has stated that the stage of dental development is more significant that the chronological age of the patient. Factors such as presence of primary teeth, eruption of second molars, and eruption of the entire permanent dentition, all impact and effect treatment time to a greater extent than chronological age.13 Gender Gender of the patient may also play a role in treatment duration. Boys have been shown to be in treatment longer than girls.1,3,14,15 Starnbach and Kaplan3 have reported that this phenomenon may be attributed to males lack of cooperation rather than some physiological difference. Since the teenage female matures earlier than the male, this too has been postulated as a cause for lack of cooperation in the male population. Although many studies have shown male treatment to last longer than females, Beckwith and colleagues did not find differences.6 They were able to show that lack of cooperation contributed to increase in treatment duration but that it did not coincide with gender. 4 Socioeconomic Status Socioeconomic status has not been thoroughly investigated and at present its relationship to treatment duration is unknown.2-4 Treatment Method Orthodontic treatment itself is fraught with variability, due to differences in treatment philosophy, diagnosis (i.e. extraction vs. non extraction), and appliances utilization. Extraction vs. Non extraction Vig et al.16 studied 5 different orthodontic offices and showed that within each office extraction treatment did take longer. Vig and colleagues also reported that when the offices were pooled together, treatment time was not significantly different between extraction and non extraction. He concluded treatment time variation was a variable between practitioners, and others have found similar results.6,17 Conversely, many have reported that extraction treatment did take longer than non extraction treatment.1,4,7,8 Skidmore et al.1 looked at consecutively treated cases by one orthodontist and found extractions prolonged treatment by 2.6 months, and delaying extractions 5 also increased treatment duration, adding an additional 5.3 months. These results are in agreement with Shia18 who stated that delaying extractions increases treatment time significantly more than extracting at the beginning of treatment. Fink and Smith7 in a multiple office study, reported that two premolar extractions increased treatment length by 4 months and four premolar extractions by 5.1 months. Alger19 found extraction cases took 4.6 months longer than non extraction cases. Thus, there is considerable evidence that extraction therapy correlates to longer active treatment time. One Phase vs. Two Phase Treatment There have been numerous reports about the differences between one and two phase treatment.8,13,20,21 Typical two phase treatment generally employs a functional appliance for the first phase of treatment, followed by a period of retention; the second phase generally requires full appliances. It has been well established that two phases of treatment take longer than a single phase.4,6,8,16,17,21 Beckwith et al.6 found that two phase treatment lasted, on average, 8 months longer than a single phase. Vig et al.16 found an even larger disparity of 13.5 months. Popowich17 reported that a single phase of treatment that included 6 headgear was much more efficient (i.e. treatment time) than Herbst therapy, followed by a second phase of full appliances. Although there seems to be considerable evidence that one phase treatment may be more favorable when related to treatment duration, two phase treatment continues to be a popular approach in the correction malocclusions. Detail and Finish The duration of treatment can certainly be affected by the amount of detail and finish at the end of treatment. The time and effort spent detail and finish of a case varies from one practitioner to another. Fink and Smith7 support the idea that there is a large variation in the amount of detail needed to finish a case. They felt that a large amount of variation found within their data could be explained by the differences in detail, because the Salzmann Index used in the study was not sensitive enough to objectively grade differences in finishing. The only index reported to have the ability grade the fine details of finish is the ABO objective grading system.22 Variation in the amount and quality of finish at the end of a case can have an impact on the overall duration of treatment. 7 Patient Cooperation Patient cooperation has been shown to be a contributing factor to lengthening treatment time.1,6-8,10 Much of what is accomplished in treatment of a case requires the help of the patient. Poor oral hygiene, missed appointments, broken appliances, and poor elastic wear have all been shown to increase treatment duration. Oral Hygiene Poor oral hygiene is a problem every practitioner faces, for fixed appliances in the mouth are more difficult to clean. Not only does poor oral hygiene contribute to an increased incidence of caries and periodontal health, but poor hygiene has been linked to longer treatment time. A likely explanation for this phenomenon would be that patients who exhibit poor hygiene are less likely to be compliant in other areas of treatment.23,24 Recent studies have confirmed a link between longer treatment times and poor oral hygiene.1,6,8,14,23,24 Broken Appointments/Appliances Broken appointments can be a major issue of concern in the orthodontic office. Robb et al.10 showed that a 8 significant amount of variability in treatment duration can be attributed to broken appointments. As the number of missed appointments increases, so in turn, will naturally prolong treatment time.1,6-8 Along with missed appointments, broken and damaged appliances also contribute to prolonged treatment time.1,6,8,10,18 O’Brien et al.8 have reported that the numbers of appliance repair was a major cause for treatment overruns. Shia18 noted that many times broken appliances not only take time to repair, but often create trauma and possible need for healing time for the patient. further extending treatment. Elastics/Headgear Compliance Elastics and headgear are often used to supplement full fixed appliances. They can be effective means to move teeth, but require the cooperation of the patient. Beckwith et al.6 noted that the use of headgear was associated with longer treatment. This may be due to lack of cooperation, or it may represent the underlying malocclusion for which the headgear was prescribed. Skidmore et al.1 also correlated poor elastic wear to longer treatment time; thus, patient compliance is an important issue for all clinicians. It is difficult to know who will be compliant in all these aspects of treatment. 9 Malocclusion Characteristics Characteristics of malocclusion can be considered dental, skeletal, or a combination of the two combined. Dental Dental occlusal classification has been shown to have significant influence upon treatment duration. Reports show that the Angle Class II malocclusion patient takes longer to than treat than the Class I malocclusion.1,4,15,17 Harrington.15 used a Deflection Index to measure the molar deflection from ideal Angle Class I. He used millimetric measurements to quantify how far the molar occlusion deviated from a class I relationship and concluded that the further the molar relationship is from Class I, the greater the increase in treatment time.15 Skidmore and associates reported maxillary crowding of at least 3mm to be a significant factor in increasing treatment duration.1 Conversely, others have not found a relationship between the amount of crowding and treatment duration.6,7 10 Skeletal Discrepancies Fink and Smith7 found that a larger ANB was associated with increase in treatment duration and amount of molar deflection. Unexpectedly, a higher mandibular plane angle contributed to decrease in the length of treatment time. They suggested that this could possibly reflect a correction of a deepened overbite rather than a true linear trend of mandibular plane angle change. Skidmore et al.1 recently noted that despite the various studies about treatment duration, few have looked at the anatomic differences in pretreatment malocclusion. Discrepancy Index The Discrepancy Index (DI) is the ABO’s current approach to summarizing the clinical features of a patient’s pretreatment condition with a quantifiable, objective list of target disorders that represent common problems associated with orthodontic diagnosis.25 History of Discrepancy Index The DI was developed over a number of years from 19982003. A panel of eight ABO directors and six former directors worked together in a series of meetings and studies that involved cases presented to the ABO for phase 11 III examination. With the information gathered from these field tests, modifications were made to the index.25 The final outcome was a number of target disorders that were chosen for use as measurements in the DI. The categories measured are as follows: Overjet- The distance between the lingual incisal edge of the most forwardly positioned maxillary incisor to the labial incisal edge of the most forwardly positioned mandibular incisor. (Fig.1) Fig 1. Overjet Measurement* Overbite- The amount the maxillary incisor overlaps vertically with the lower incisor. (Fig. 2) *All figures modified from Cangialosi TJ. et al. Am J Orthod Dentofacial Orthop 2004;125:270-278. 12 Fig 2. Overbite Measurement Anterior Openbite- If the maxillary and mandibular incisors are edge to edge or open. (Fig. 3) Fig 3. Anterior Openbite Measurement 13 Lateral Openbite- Any maxillary tooth from first premolar to third molar in an open bite relationship (Fig. 4) Fig 4. Lateral Openbite Measurement Crowding- The most crowded dental arch is scored (Fig.5) Fig 5. Crowding Occlusion- The Angle occlusal relationship is used to score the buccal occlusion. When the mesial buccal cusp of the maxillary first molar is found anywhere in between the two buccal cusps of the mandibular first molar it is classified 14 as class I. If there is a cusp to cusp relationship it is classified as end on. If the mesial buccal cusp of the maxillary first molar is beyond cusp to cusp, anterior or posterior, the case is classified full step class II or class III respectively. (Fig. 6) Fig 6. Occlusion Lingual Posterior Crossbite- Every maxillary posterior tooth in lingual crossbite is measured. (Fig. 7) Fig 7. Lingual Posterior Crossbite 15 Buccal Posterior Crossbite- All maxillary teeth from first premolar to third molar in complete buccal crossbite are noted. (Fig. 8) Fig 8. Buccal Posterior Crossbite There is also a category labeled “other.” This section of the DI is used to score any other clinical entity that may contribute to case complexity. Additional points may be added for ectopic eruption, missing or supernumerary teeth, transposition, anomalies of tooth size and shape, CR-CO discrepancies, skeletal asymmetry, excess curve of Wilson.25 These are relatively common findings in orthodontics but were not accounted for in the previous categories. 16 Cephalometric measurements used are the ANB angle, IMPA, and SN-GoGn. (Fig. 9) Fig 9. Cephalometric Measurements The DI was not designed to assess treatment need. The primary purpose of the DI was an objective way to measure the complexity of the treatment.25 Currently it is used for case selection for phase III of ABO board certification. Board candidates present a total of 6 cases, 3 must have a DI score of at least 20 and 3 must have a DI score of at 17 least 10. The candidate can measure the cases before submission with the board verifying the scores. The ability to more accurately predict treatment duration would be a valuable asset to orthodontists. This area of orthodontic research is still relatively young. Many studies have looked at the multiple variables such as socioeconomic characteristics, treatment method, patient cooperation, and malocclusion characteristics. The purpose of this study is to look at the influence of pretreatment malocclusion on treatment duration. The pretreatment malocclusion will be defined by the Discrepancy Index. 18 References 1. Skidmore KJ, Brook KJ, Thomson WM, Harding WJ. Factors influencing treatment time in orthodontic patients. Am J Orthod Dentofacial Orthop 2006;129:230-238. 2. Egolf RJ, BeGole EA, Upshaw HS. Factors associated with orthodontic patient compliance with intraoral elastic and headgear wear. Am J Orthod Dentofacial Orthop 1990;97:336348. 3. Starnbach HK, Kaplan A. Profile of an excellent orthodontic patient. Angle Orthod 1975;45:141-145. 4. Turbill EA, Richmond S, Wright JL. The time-factor in orthodontics: what influences the duration of treatments in National Health Service practices? Community Dent Oral Epidemiol 2001;29:62-72. 5. Weiss J, Eiser HM. Psychological timing of orthodontic treatment. Am J Orthod 1977;72:198-204. 6. Beckwith FR, Ackerman RJ, Jr., Cobb CM, Tira DE. An evaluation of factors affecting duration of orthodontic treatment. Am J Orthod Dentofacial Orthop 1999;115:439-447. 7. Fink DF, Smith RJ. The duration of orthodontic treatment. Am J Orthod Dentofacial Orthop 1992;102:45-51. 8. O'Brien KD, Robbins R, Vig KW, Vig PS, Shnorhokian H, Weyant R. The effectiveness of Class II, division 1 treatment. Am J Orthod Dentofacial Orthop 1995;107:329-334. 9. Popowich K, Nebbe B, Heo G, Glover KE, Major PW. Predictors for Class II treatment duration. Am J Orthod Dentofacial Orthop 2005;127:293-300. 10. Robb SI, Sadowsky C, Schneider BJ, BeGole EA. Effectiveness and duration of orthodontic treatment in adults and adolescents. Am J Orthod Dentofacial Orthop 1998;114:383-386. 11. Proffitt WR Contemporary Orthodontics Second Edition. St Louis MO, Mosby, 2000. 19 12. Harris EF, Dyer GS, Vaden JL. Age effects on orthodontic treatment: skeletodental assessments from the Johnston analysis. Am J Orthod Dentofacial Orthop 1991;100:531-536. 13. Gianelly AA. One-phase versus two-phase treatment. Am J Orthod Dentofacial Orthop 1995;108:556-559. 14. Kreit LH, Burstone C, Delman L. Patient cooperation in orthodontic treatment. J Am Coll Dent 1968;35:327-332. 15. Harrington CF. Deflection index and duration of treatment. master's thesis, University of Saint Louis, Saint Louis MO, 2004 (unpublished) 16. Vig PS, Weintraub JA, Brown C, Kowalski CJ. The duration of orthodontic treatment with and without extractions: a pilot study of five selected practices. Am J Orthod Dentofacial Orthop 1990;97:45-51. 17. Popowich K. Comparison of Class I and Class II Treatment Duration Among Three Different Orthodontic Practices. Seminars of Orthodontics 2006;12:52-59. 18. Shia GJ. Treatment overruns. J Clin Orthod 1986;20:602604. 19. Alger DW. Appointment frequency versus treatment time. Am J Orthod Dentofacial Orthop 1988;94:436-439. 20. O'Brien K, Wright J, Conboy F, Sanjie Y, Mandall N, Chadwick S et al. Effectiveness of early orthodontic treatment with the Twin-block appliance: a multicenter, randomized, controlled trial. Part 1: Dental and skeletal effects. Am J Orthod Dentofacial Orthop 2003;124:234-243; quiz 339. 21. Tulloch JF, Proffit WR, Phillips C. Outcomes in a 2phase randomized clinical trial of early Class II treatment. Am J Orthod Dentofacial Orthop 2004;125:657-667. 22. Casko JS, Vaden JL, Kokich VG, Damone J, James RD, Cangialosi TJ et al. Objective grading system for dental casts and panoramic radiographs. American Board of Orthodontics. Am J Orthod Dentofacial Orthop 1998;114:589599. 20 23. El-Mangoury NH. Orthodontic cooperation. Am J Orthod 1981;80:604-622. 24. Nanda RS, Kierl MJ. Prediction of cooperation in orthodontic treatment. Am J Orthod Dentofacial Orthop 1992;102:15-21. 25. Cangialosi TJ, Riolo ML, Owens SE, Jr., Dykhouse VJ, Moffitt AH, Grubb JE et al. The ABO discrepancy index: a measure of case complexity. Am J Orthod Dentofacial Orthop 2004;125:270-278. 21 CHAPTER 3: JOURNAL ARTICLE Abstract A constant question in any orthodontic office is “When do I get my braces off?” A better understanding of those factors that influence treatment duration would be a great benefit for both the patient and the doctor. The purpose of this retrospective study was to look at the influence of pretreatment malocclusion on treatment duration. The severity of malocclusion was defined by the American Board of Orthodontics’ Discrepancy Index. Data were gathered from one orthodontic office on 98 patients treated with comprehensive orthodontics. The patient sample was collected so as to eliminate, to the greatest degree possible, the variability of patient cooperation. The DI measurements were used to collect pretreatment information and relate it to treatment duration. time was 22.1 months. The average treatment Six of the fourteen pretreatment variables were found to be significant in contributing to treatment variability: Class II malocclusion, buccal posterior crossbite, palatal impingement, total DI score, ANB angle, and overjet. Quality of the finished cases was not evaluated. 22 Introduction A constant question in any orthodontic office is “When do I get my braces off?” A better understanding of those factors that influence treatment duration would be a great benefit for both the patient and the doctor. Patients are anxious to be finished with the braces and see the outcome of their investment in orthodontics. Treatment length can have an impact on family life, missed school or work, finances. Orthodontists would benefit in that greater accuracy in predicting treatment duration, could enhance office management. This would help balance scheduling, inventory and allow an office to run at full capacity. Patients are more likely to be happy when appliances are removed at the time indicated at the original diagnosis. There have been a number of studies that have looked at the factors involved in treatment duration.1-3 Skidmore et al. classified these factors into four broad categories: Sociodemographic characteristics, malocclusion characteristics, treatment method, and patient cooperation.3 This study will focus on the pretreatment malocclusion. Pretreatment malocclusion characteristics studied previously include ANB, mandibular plane angle, crowding, overjet, occlusion, and overall index score.1-9 23 It has been a consistent finding that Class II treatment takes longer than Class I.3,4,6,9,10 Fink and Smith found that higher ANB and Salzmann score correlated to longer treatment time.2 Skidmore noted that crowding greater than 3mm in the maxillary arch increased treatment duration.3 Robb and others have found a correlation with overjet.7,10 O’Brien et al. reported the Peer Assessment Rating (PAR) score was an indicator of longer treatment time while Popowich was unable to substantiate this.5,6 The use of an occlusal index is one way to study and quantify a malocclusion, and there have been a number of different indices developed for a variety of reasons. Some study treatment need, while others look at pre and post treatment outcomes.11-14 Additionally there have been studies that have attempted to correlate indices such as the PAR, Salzmann, and Deflection Index to treatment duration.4,12,15,16 The American Board of Orthodontics has in recent years developed an index for the purpose of evaluating case selection to be presented to the board for certification, it is the Discrepancy Index (DI).17 The goal of the DI was not to assess treatment need but treatment complexity. The purpose of this retrospective study was to look at the influence of the pretreatment malocclusion on treatment duration. The severity of malocclusion will be 24 defined by the American Board of Orthodontics Discrepancy Index. Materials and Methods The sample of the present study was obtained from the files of one orthodontic office. Pretreatment lateral cephalometric radiographs, pretreatment plaster models, treatment plans, and progress notes were examined for 98 patients that fit the selection criteria. The selection criteria included both inclusion criteria and exclusion criteria. Inclusion Criteria: - Finishing elastics worn no more than 3 months. - Correction of Class II with Herbst appliance for 8-10 months prior to bonded appliances. - Patient started and completed treatment in the same office. Exclusion Criteria: - Extraction of permanent teeth. - The use of Class II intermaxillary elastics. - Headgear use. - Negative chart entries due to lack of cooperation or poor oral hygiene. 25 - More than one chart entry signifying broken appliances, including brackets. - More than on chart entry signifying more than one missed appointment. The orthodontist was located in the Midwest and is board certified in the specialty of orthodontics. All measurements on both the study models and the lateral cephalometric radiographs were completed by one examiner. The study models were measured with a ruler and digital caliper according to instructions by Cangialosi et al.17 as follows: • Overjet-the distance between the lingual incisal edge of the most forwardly positioned maxillary incisor to the labial incisal edge of the most forwardly positioned mandibular incisor. • Overbite-The amount the maxillary incisor overlaps vertically with the lower incisor. • Anterior Openbite- If the maxillary and mandibular incisors are edge to edge or open. • Lateral Openbite- Any maxillary tooth from first premolar to third molar in an open bite relationship. 26 • Crowding- Only the most crowded dental arch is scored. • Occlusion- The Angle occlusal relationship is used to score the buccal occlusion. When the mesial buccal cusp of the maxillary first molar is found anywhere in between the two buccal cusps of the mandibular first molar it is classified as Class I. If there is a cusp to cusp relationship it is classified as end on. If the mesial buccal cusp of the maxillary first molar is beyond cusp to cusp the case is classified full step Class II or Class III. • Lingual Posterior Crossbite- Every maxillary posterior tooth in lingual crossbite is measured. • Buccal Posterior Crossbite- Every maxillary tooth from first premolar to third molar in complete buccal crossbite is measured. The cephalometric radiographs were measured using acetate paper and lead pencil. The measures obtained included ANB, SN-GoGn, and IMPA. Descriptive statistics were used to characterize the data set. Both parametric and non-parametric statistics explored the relationships among key variables. Bivariate correlation methods were used to describe the relationship 27 between continuous and categorical variables when appropriate. Chi square statistic was used to compare nominal variables. A one way ANOVA was used to describe the relationships between the various types of occlusions used as the dependent variable and the independent variables of DI score, overjet, palatal impingement, overbite, crowding, ANB, IMPA, SN-GoGn in the predictive model. The alpha level was established at the conventional level (p<.05). Post Hoc Tukey Honestly Significant Differences (HSD) was used to discriminate between occlusal classifications on significant variables. Receiver Operator Curves (ROC) were used to look at predictive nature of Class II malocclusion. In the first curve Class II was dichotomized as Class II vs. other classifications. A ROC curve was then performed on the dichotomized classifications and treatment time as a continuous variable. dichotomized at 15. In the second curve total DI was Fifteen points was chosen in an attempt to find a reasonable number which would represent the midpoint from what the ABO defines as a more complex case (20 points) and a more basic case (10 points). An ROC curve was then performed on the dichotomized DI score with 28 treatment time used as the continuous variable. The data was analyzed using SPSS14. Results Table I shows the mean values for all patients as well as Class I and Class II separately. The average treatment time for patients in the study was 22.1 months with a total average DI score of 12.6 points. Class I patients average treatment time was 19.9 months with an average DI score of 9.9 points. Class II patients showed higher treatment time and DI score at 25.6 months and 16.9 points respectively. The average age for patients in the study at the start of treatment was 14.8 years. Chi square analysis showed no difference between age and gender. Tables II and III show the correlation relationship of all variables with treatment time using either a Pearson’ r or a Spearman’ rho as the data type indicates. DI score (r=.52), Class II malocclusion (rho=.43), ANB (r=.42), overjet (r=.28), palatal impingement (rho=.43), and posterior buccal crossbite (rho=.28) were found to be significant (p<.05). Of these variables, DI score, Class II malocclusion, palatal impingement, and ANB showed a 29 moderate relationship with treatment time. No other variables studied correlated with length of treatment. The DI score showed the highest correlation to treatment time (r=.52, p<.00). The Class II patients were further divided into mild Class II and Class II. Table IV shows an Analysis of Variance (ANOVA) which compares occlusal classification types with all variables studied. Significant ANOVA results show there are differences among occlusal classifications. Table V shows the Post Hoc Tukey HSD test results indicate which occlusal classifications are different with these variables. The Class II differed significantly from the mild Class II and Class I patients. While the average treatment time for the study was 22.1 months, a significant difference was found between Class I and Class II patients. Predictive curves using ROC were used to model the comparison. Variables that account for greater than 50% of the variance are considered to be predictive. The higher the percentage the variable accounts for on the graph or conversely, that the variable accounts for area under the curve, the more predictive the variable. The percentage of prediction of these variables can be accounted for by the amount of variance under the curve that the variable is able to predict. 30 Figure 10A is the ROC showing treatment time and Class II malocclusion with the area under the curve at 0.757. Figure 11A is the ROC showing treatment time and the dichotomized DI score at 15 points. The area under the curve for DI score was 0.849. These results indicate that Class II occlusion as well as total DI score can be predictive of treatment time. Discussion The purpose of this study was to look at pretreatment malocclusion and its’ effect on treatment duration. The study was designed to eliminate as much as possible the influence patient cooperation would have on treatment duration. It was found that Class II molar malocclusion, increased overjet, total DI score, ANB, buccal posterior crossbite, and palatal impingement all predict longer treatment times. The average treatment time in this study was 22.1 months. The Class I patients averaged 19.9 months and Class II 25.6 months. Other Class II studies that included 2-phase treatment were 28.61 and 31.2.8 When 2-phase treatment was excluded, treatment times of 2218, 23.12, and 23.53 have been reported. Most Class II patients in this study were treated with fixed Herbst appliances, a method 31 of Class II correction that does not require patient cooperation. Many prior studies have noted that males take longer to treat than females.3,4,19,20 Starnbach and Kaplan attributed this phenomenon to the males lack of cooperation.20 The present study attempted to eliminate the variable of patient compliance, this may be one of the reasons there was no difference in treatment time between males and females. Previous studies have reported that age was not a factor in treatment time, and this would appear to be confirmed in the present study.1,2,10 This study represents the first time the DI has been correlated to treatment time. Fink and Smith used the Salzmann Index and found a correlation.2,21 the PAR with mixed results.4-6 Others have used The present study also found that the DI did correlate with treatment time. The ROC (Figure 11A) showed that a DI score of at least 15 points would predict treatment time longer than 22.1 months 84.9% of the time. The curve for Class II (Figure 10A) would predict the same thing at 75.7%. Overall, this was of some value when used to help predict length of treatment time. The index is relatively easy to measure and only requires models and a cephalometric radiograph. Thus, the DI may be used as an aid when one wishes to predict treatment 32 duration. The finished cases were not evaluated for quality. Conclusions Based on the findings of this study which included 98 patients from one orthodontic office the following conclusions may be drawn: 1. Pretreatment malocclusion characteristics which significantly contributed to treatment time were DI score, class II occlusion, ANB, overjet, palatal impingement, and posterior buccal crossbite. 2. Patients with Class II malocclusion treatment time averaged almost 6 months longer than Class I. 3. Age and sex did not influence treatment duration. 4. The DI score and Class II malocclusion showed similar predictive value. 33 Literature Cited 1. Beckwith FR, Ackerman RJ, Jr., Cobb CM, Tira DE. An evaluation of factors affecting duration of orthodontic treatment. Am J Orthod Dentofacial Orthop 1999;115:439-447. 2. Fink DF, Smith RJ. The duration of orthodontic treatment. Am J Orthod Dentofacial Orthop 1992;102:45-51. 3. Skidmore KJ, Brook KJ, Thomson WM, Harding WJ. Factors influencing treatment time in orthodontic patients. Am J Orthod Dentofacial Orthop 2006;129:230-238. 4. Harrington CF. Deflection index and duration of treatment. master's thesis, University of Saint Louis, Saint Louis MO, 2004 5. O'Brien KD, Robbins R, Vig KW, Vig PS, Shnorhokian H, Weyant R. The effectiveness of Class II, division 1 treatment. Am J Orthod Dentofacial Orthop 1995;107:329-334. 6. Popowich K. Comparison of Class I and Class II Treatment Duration Among Three Different Orthodontic Practices. Seminars of Orthodontics 2006;12:52-59. 7. Popowich K, Nebbe B, Heo G, Glover KE, Major PW. Predictors for Class II treatment duration. Am J Orthod Dentofacial Orthop 2005;127:293-300. 8. Vig PS, Weintraub JA, Brown C, Kowalski CJ. The duration of orthodontic treatment with and without extractions: a pilot study of five selected practices. Am J Orthod Dentofacial Orthop 1990;97:45-51. 9. Vig KW, Weyant R, Vayda D, O'Brien K, Bennett E. Orthodontic process and outcome: efficacy studies-strategies for developing process and outcome measures: a new era in orthodontics. Clin Orthod Res 1998;1:147-155. 10. Robb SI, Sadowsky C, Schneider BJ, BeGole EA. Effectiveness and duration of orthodontic treatment in adults and adolescents. Am J Orthod Dentofacial Orthop 1998;114:383-386. 34 11. Richmond S, Shaw WC, Roberts CT, Andrews M. The PAR Index (Peer Assessment Rating): methods to determine outcome of orthodontic treatment in terms of improvement and standards. Eur J Orthod 1992;14:180-187. 12. Salzmann JA. Handicapping malocclusion assessment to establish treatment priority. Am J Orthod 1968;54:749-765. 13. O'Brien KD, Shaw WC, Roberts CT. The use of occlusal indices in assessing the provision of orthodontic treatment by the hospital orthodontic service of England and Wales. Br J Orthod 1993;20:25-35. 14. Shaw WC, Richmond S, O'Brien KD. The use of occlusal indices: a European perspective. Am J Orthod Dentofacial Orthop 1995;107:1-10. 15. Richmond S, Shaw WC, O'Brien KD, Buchanan IB, Jones R, Stephens CD et al. The development of the PAR Index (Peer Assessment Rating): reliability and validity. Eur J Orthod 1992;14:125-139. 16. Salzmann JA. Editorial: Seriously handicapping orthodontic conditions. Am J Orthod 1976;70:329-330. 17. Cangialosi TJ, Riolo ML, Owens SE, Jr., Dykhouse VJ, Moffitt AH, Grubb JE et al. The ABO discrepancy index: a measure of case complexity. Am J Orthod Dentofacial Orthop 2004;125:270-278. 18. Alger DW. Appointment frequency versus treatment time. Am J Orthod Dentofacial Orthop 1988;94:436-439. 19. Kreit LH, Burstone C, Delman L. Patient cooperation in orthodontic treatment. J Am Coll Dent 1968;35:327-332. 20. Starnbach HK, Kaplan A. Profile of an excellent orthodontic patient. Angle Orthod 1975;45:141-145. 21. Salzmann JA. Definition and criteria of handicapping malocclusion: a progress report. Am J Orthod 1966;52:209212. 35 APPENDIX Table I Mean Values of Study Sample with Similarities and Differences for Malocclusion Classification (N=98) Variable Class I Class II Total ________________________________________________________________________ Age Treatment Time DI score ANB IMPA SN-GoGn Overjet Overbite Crowding 14.9 19.9 9.9 3.0 92.6 33.7 2.7 2.8 3.3 14.8 25.6 16.9 4.0 94.2 31.4 4.3 4.2 3.8 14.8 22.1 12.6 3.4 93.2 32.9 3.4 3.3 3.4 Table II Correlation of Continuous Variables of Class I and Class II Patients with Treatment Time (N=98) Variable Pearson correlation “r” Value p value Age Total DI score ANB IMPA SN-GoGn Overjet Overbite Crowding -.08 .52** .42** .02 .07 .28* .17 .15 NS .000 .000 NS NS .005 NS NS 36 Table III Correlation of Categorical Variables of Class I and Class II Patients with Treatment Time (N=98) Variable Spearman’s rho p value ________________________________________________________________________ Palatal Impingement Anterior Crossbite Anterior Openbite Edge to Edge Openbite Lateral Openbite Lingual Posterior Crossbite Buccal Posterior Crossbite Crowding location Class II occlusion .43** .01 .01 -.05 .09 .15 .28* .13 .43** .000 NS NS NS NS NS .005 NS .000 Table IVa Total Treatment Time and Other Discriminating Variables Found in an Analysis of Variance for Occlusal Classification Defined by 3 Groups (Class I, Mild Class II*, and Class II) Independent Variable Sum of Squares mean square F,df p<.05 Treatment Time Between Groups 756.5 Within Groups 2700.4 378.2 13.3, 2 .000 Total DI Between Groups 1164.2 Within Groups 4160.2 582.1 12.9, 2 .000 Overjet Between Groups 69.5 Within Groups 252.7 34.8 13.1, 2 .000 Overbite Between Groups 46.0 Within Groups 171.8 23.0 12.7, 2 .000 Palatal Impingement Between Groups 4.2 Within Groups 10.5 2.1 18.7, 2 .000 ANB Between Groups 29.9 Within Groups 406.7 15.0 3.5, 2 .034 *Mild Class II- half step Class II 37 Table V Tukey HSD Post Hoc Test Differences Found Between Class II and Other Classifications of Variables in the Analysis of Variance (Class I, Mild Class II*, Class II) Dependant Variable Class II Class I or Mild Class II Treatment Time Class II Class I, mild Class II Total DI Class II Class I, mild Class II Overjet Class II Class I, mild Class II Overbite Class II Class I, mild Class II Palatal Impingement Class II Class I, mild Class II ANB Class II Class I *Mild Class II- half step Class II 38 1.0 Sensitivity 0.8 0.6 0.4 0.2 0.0 0.0 0.2 0.4 0.6 0.8 1.0 1 - Specificity Diagonal segments are produced by ties. Figure 10A: Receiver Operator Curve of Class II Malocclusion and Treatment Time 39 1.0 Sensitivity 0.8 0.6 0.4 0.2 0.0 0.0 0.2 0.4 0.6 0.8 1.0 1 - Specificity Diagonal segments are produced by ties. Figure 11A: Receiver Operator Curve for the Dichotomized DI Score (>15) and Treatment Time 40 VITA AUCTORIS Bradley G. Simister was born in Las Vegas, NV on October 10, 1975. his family. Brad was the fourth of five children in He graduated from Bonanza High School in 1994. Following a year of college in Salt Lake City, he served a two year mission in Madrid, Spain for The Church of Jesus Christ of Latter-Day Saints. In 1997 he matriculated at Brigham Young University graduating with a B.A. of Science in 2000. He then attended Creighton Dental School graduating with a D.D.S. in 2004. After dental school Brad was accepted into the Orthodontic Program in Saint Louis University and plans to graduate in December 2006. He will be in private practice St. George, UT. Brad married Sondra Jacobsen August 8, 1998. They are the parents of four children. 41