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Interpersonal Psychotherapy for Group Denise E. Wilfley, Ph.D, Juliette M. Iacovino, M.A., Monica S. Mills, M.A., & R. Robinson Welch, Ph.D. Washington University in St. Louis School of Medicine Friday, June 24, 2011 R29MH051384; R01MH064153; K24MH070446; T32HL00745626 Disclosures • Research Support – Shire Pharmaceuticals • Advisory/Consultant – – – – GlaxoSmithKline Consumer Healthcare Minnesota Obesity Consortium United Health Group, Childhood Obesity Initiative Wellspring Healthy Living Academy Theoretical Underpinnings of IPT for Eating Disorders • Assumption: Eating disorders develop within social and interpersonal contexts • Relationships between the patient and significant others impact the maintenance of the disorder and response to treatment • Focus: Identifying and modifying the interpersonal context in which the eating problem has been developed and maintained Wilfley, Comprehensive Textbook of Psychiatry Volume Two. 8th Ed., 2005 An Eating Disorder-Specific Model of IPT Grief, Role Transition, Interpersonal Dispute &/or Interpersonal Deficit Trigger … Individual Vulnerability Factors Negative Social Evaluation General Cultural Values Regarding Eating, Shape, and Weight Specific to Eating, Shape, or Weight Shape and WeightBased Self Worth Individual Vulnerability Factors Outcome Expectancies Self Disturbance Negative Self (may include Body) Evaluation and Associated Negative Affect Regarding Eating, Shape, and Weight Eating Disorder Behaviors Self-starvation; Dietary Restriction and other Extreme Weight Control Behaviors; Binge Eating Rieger, VanBuren, Bishop, Tanofsky-Kraff, Welch, & Wilfley. Clin Psychol Rev, 2010 Rationale for IPT-G • “Interpersonal laboratory” – Multiple opportunities to practice interpersonal skills – Skills can be readily applied to outside relationships • Breaks patterns of social isolation and stigma • Provides a social corrective and supportive atmosphere • Cost-effective treatment modality Wilfley, Frank, Welch, Spurrell, & Rounsaville, Psychotherapy Research, 1998 Key Elements of the Group Format • Semi-structured • Circumscribed treatment focus • Focused on changing outside interpersonal relationships • Active group leadership Group Composition • 7-10 group members • Homogeneous groups (e.g., diagnosis) – – – – – Mutual motivation Rapid cohesion Common target problems Immediately feeling understood More time for applied work • Heterogeneous with regard to interactional style Relevant Considerations in Translating IPT from an Individual to a Group Format • Provide a focus on each individual’s problem area(s) – Individual meetings • Pre-group: Conduct interpersonal inventory; identify problem area(s) & translate into specific goals; prepare for group “Throughout the time that you are in the group, it will be helpful for you to begin making connections with people in your outside social life. Use the group to share how your efforts are progressing. As you work to get your binge eating under control, you will feel better about yourself and will be more open for relationships with others” • Mid-group: Discuss progress; refine interpersonal goals • Post-group: Individualized plan for continued work • Attend to group process Overview of Treatment Structure PRE-GROUP GROUP SESSIONS INITIAL ASSESS 1 PRE-GROUP MEETING POST-GROUP MIDDLE 5 6 10 11 MID-GROUP MEETING FINAL 15 16 20 ASSESS POST-GROUP MEETING The Phases of IPT and Stages of Group Development Phase of IPT INITIAL Stage of Group Development Stage 1: Engagement - Create a functioning group Stage 2: Differentiation - Resolve conflicts MIDDLE Stage 3: Work - Focus on individual issues while encouraging inter-member work FINAL Stage 4: Termination - Identify and reinforce termination themes Wilfley et al., Psychotherapy Research, 1998 Common IPT Techniques Translated to Group Format • Clarification – Group member can repeat or rephrase a statement • Communication analysis – Group can suggest alternatives to poor communication • Summarizing – Review important group themes that emerge – Highlight themes related to members’ identified goals Two Models of Symptom Maintenance CBT MODEL FOR BINGE EATING Societal Pressure for Thinness IPT MODEL FOR BINGE EATING Interpersonal Problems IPT Distorted Attitudes Toward Eating, Shape, and Weight Low Self-Esteem Dysphoria CBT Dietary Restraint Bingeing Food Used to Cope With Negative Feelings Bingeing Wilfley et al., J Gender Culture Health, 1997 IPT-G for Binge Eating Disorder is Efficacious • Superior to wait-list (Wilfley et al., JCCP, 1993) • Comparable to Group CBT (Wilfley et al., JCCP, 1993; Arch Gen Psychiatry, 2002) • Comparable short- and long-term abstinent rates to individual CBT guided self help and individual IPT; superior long-term rates to individual Behavioral Weight Loss (Wilson, Agras, & Wilfley, Arch Gen Psychiatry 2010) IPT-G Long-term Efficacy for BED: 100 100 90 90 80 80 70 70 60 60 Recovered, % Remitted, % 4-6 Year Follow-up from Wilfley et al. (2002) Study 50 40 30 20 50 40 30 20 10 10 0 0 Pretreatment Posttreatment One-Year Follow- Long-Term FollowUp Up Cognitive-Behavioral Therapy Pretreatment Posttreatment One-Year Follow- Long-Term FollowUp Up Interpersonal Psychotherapy Adaptations of IPT-G • Interpersonal focus relevant for other populations • IPT-G shown to be efficacious for a number of problems Efficacious Applications of IPT-G: Adults • Major depression (Levkovitz, J Affect Disord, 2000; Bolton et al., JAMA, 2003) • Female prisoners with co-morbid depression and substance use disorder (Johnson & Zlotnick, J Substance Abuse Treat, 2008) • Post-traumatic stress disorder (Krupnick et al., Psychother Res, 2008) • Eating disorder not otherwise specified (Nevonen & Broberg, Eur Eat Disord Rev, 2005) • Bulimia nervosa (Nevonen & Broberg, Int J Eat Disord, 2006) IPT-G in Uganda: Adults with Depression • Cluster-randomized RCT compared IPT-G to no-treatment • Group leaders were community members with no previous counseling experience and were trained in IPT-G • IPT-G associated with significantly greater reductions in depressive symptoms & dysfunction • Significantly fewer in IPT-G met criteria for depression • All differences maintained at 6-month follow-up Bolton et al., JAMA, 2003 Adaptations of IPT-G: Adolescents • Group IPT for adolescents: IPT-AG (Mufson et al., Am J Psychother, 2004; Child and Adol Mental Health, 2010) – IPT-A adapted to a group format – Pilot study found no differences between IPT-AG and IPT-A in reducing symptoms of depression – Sig. greater improvements in global functioning in IPT-AG – Maintained at 4-month follow-up • IPT-adolescent skills training (IPT-AST) – Prevention for adolescents at high-risk for depression – Superior to treatment-as-usual school counseling maintained at 6-month follow-up (Young et al., J Child Psychol Psychiatry, 2006) – Superior to school counseling post-intervention but not at 12month follow up (Young et al., Depress Anxiety, 2010) IPT-G: Adolescents IPT for the Prevention of Excess Weight Gain (IPT-WG) • Adolescent girls at risk for adult obesity – BMI≥85th percentile – Report ≥1 loss of control (LOC) eating episode in past month • Why IPT-G? – Efficacy for binge eating disorder in adults (Wilfley et al., Arch Gen Psychiatry, 2002) – Overweight youth are target of negative social interactions – Adolescent peer relationships crucial to self-evaluation IPT-WG: Proposed Mechanism of Change Model Interpersonal Problems IPT Improve Interpersonal Functioning Negative Affect Decrease Negative Affect LOC Eating Reduce LOC Eating Excess Weight Gain Weight Stabilization Tanofsky-Kraff, Wilfley et al., Obesity 2007 < expected BMI growth (%) 1y Follow-Up: Less than Expected BMI Growth 90 * 75 60 45 30 15 0 IPT-WG *p=0.03, adjusted for age and race HE Tanofsky-Kraff, Wilfley et al., Int J Eat Disord, 2009 Greater Reductions in LOC Episodes IPT-WG HE LOC Episodes 8 6 4 2 0 1 Baseline Group x time, p = 0.04, Partial η2=0.12, adjusted for age and race 2 6m Follow-up Tanofsky-Kraff, Wilfley et al., Int J Eat Disord, 2009 IPT-WG: Future Directions POWER-UP: Preventing Weight Gain and Enhancing Relationships in Underserved Communities Funded by the National Center for Mental Health Disparities • There is a need to disseminate evidence-based treatments into community settings • Focus groups will inform adapted treatment manuals for African-American and Latina girls • We will train community leaders to deliver IPT-WG in two community clinics Conclusions • IPT-G is an evidence-based treatment that has been successfully adapted for a number of problems • No evidence to suggest that IPT-G is less efficacious than individual IPT, and a number of strengths exist in the group format • IPT-G is ripe for larger RCTs, comparative effectiveness trials, and dissemination and implementation studies • Future research should examine mediators and moderators of change, as well as the relative cost-effectiveness of the group modality References Bolton, P., Bass, J., Neugebauer, R., Verdeli, H., Clougherty, K. F., Wickramaratne, P., et al. (2003). Group interpersonal psychotherapy for depression in rural Uganda. JAMA: The Journal of the American Medical Association, 289(23), 3117-3124. Johnson, J. E., & Zlotnick, C. (2008). A pilot study of group interpersonal psychotherapy for depression in substance-abusing female prisoners. Journal of Substance Abuse Treatment, 34(4), 371-377. Krupnick, J. L., Green, B. L., Stockton, P., Miranda, J., Krause, E., & Mete, M. (2008). Group interpersonal psychotherapy for low-income women with posttraumatic stress disorder. Psychother Res, 18(5), 497-507. Levkovitz, Y., Shahar, G., Native, G., Hirsfeld, E., Treves, I., Krieger, I., et al. (2000). Group interpersonal psychotherapy for patients with major depression disorder - pilot study. Journal of Affective Disorders, 60(3), 191-195. Mufson, L., Gallagher, T., Dorta, K. P., & Young, J. F. (2004). A group adaptation of interpersonal psychotherapy for depressed adolescents. Am J Psychother, 58(2), 220-237. Mufson, L. (2010). interpersonal psychotherapy for depressed adolescents (IPT- A): extending the reach from academic to community settings. Child and Adolescent Mental Health, 15(2), 66-72. Nevonen, L., & Broberg, A. G. (2005). A comparison of sequenced individual and group psychotherapy for eating disorder not otherwise specified. European Eating Disorders Review, 13(1), 29-37. References (cont) Nevonen, L., & Broberg, A. G. (2006). A comparison of sequenced individual and group psychotherapy for patients with bulimia nervosa. International Journal of Eating Disorders, 39(2), 117-127. Rieger, E., VanBuren, D.J., Bishop, M., Tanofsky-Kraff, M., Welch, R., Wilfley , D.E. (2010). An eating disorder-specific model of interpersonal psychotherapy (IPT-ED): Causal pathways and treatment implications, Clin Psychol Rev, 30(4), 400-10. Tanofsky-Kraff, M., Wilfley, D. E., Young, J. F., Mufson, L., Yanovski, S. Z., Glasofer, D. R., et al. (2009). A pilot study of interpersonal psychotherapy for preventing excess weight gain in adolescent girls at-risk for obesity. Int J Eat Disord. Tanofsky-Kraff M., Wilfley D.E., Young J.F., Mufson L, Yanovski S.Z., Glasofer D.R., Salaita C.G. (2007). Preventing excessive weight gain in adolescents: Interpersonal psychotherapy for binge eating. Obesity, 15(6), 1345 - 1355. Wilfley, D.E. (2005). Interpersonal psychotherapy. In: Kaplan & Sadock’s comprehensive textbook of psychiatry volume two. 8th ed., (Sadock BJ, Sadock VA, eds.), Lippincott Williams & Wilkins, Baltimore, pp 2610-2619. Wilfley, D. E., Agras, W. S., Telch, C. F., Rossiter, E. M., Schneider, J. A., Cole, A. G., et al. (1993). Group cognitive-behavioral therapy and group interpersonal psychotherapy for the nonpurging bulimic individual: A controlled comparison. J Consult Clin Psychol, 61(2), 296-305. References (cont) Wilfley, D., Frank, M., Welch, R., Spurrell, E., & Rounsaville, B. (1998). Adapting interpersonal psychotherapy to a group format (IPT-G) for binge eating disorder: Toward a model for adapting empirically supported treatments. Psychotherapy Research, 8(4), 379 - 391. Wilfley, D. E., MacKenzie, K. R., Welch, R. R., Ayres, V. E., & Weissman, M. M. (2000). Interpersonal Psychotherapy for Group. New York: Basic Books. Wilfley, D. E., Welch, R. R., Stein, R. I., Spurrell, E. B., Cohen, L. R., Saelens, B. E., et al. (2002). A randomized comparison of group cognitive-behavioral therapy and group interpersonal psychotherapy for the treatment of overweight individuals with binge-eating disorder. Arch Gen Psychiatry, 59(8), 713-721. Wilson, G. T., Wilfley, D. E., Agras, W. S., & Bryson, S. W. (2010). Psychological treatments of binge eating disorder. Arch Gen Psychiatry, 67(1), 94-101. Young, J. F., Mufson, L., & Davies, M. (2006). Efficacy of interpersonal psychotherapy-adolescent skills training: An indicated preventive intervention for depression. Journal of Child Psychology and Psychiatry, 47(12), 1254-1262. Young, J. F., Mufson, L., & Gallop, R. (2010). Preventing depression: A randomized trial of interpersonal psychotherapy-adolescent skills training. Depression & Anxiety, 27(5), 426-433.