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Title: The potential of case study methodology in psychotherapy research: exploring the possibilities Presenters: Mattias Desmet, Reitske Meganck, Shana Cornelis, Jochem Willemsen Discussant: Shigeru Iwakabe Although single case studies have a long-standing image of being pseudoscientific, it is argued that they are crucial for advancements in understanding the process of psychotherapy (APA, 2006; McLeod & Elliott, 2011; Iwakabe, 2013). Within this context more systematic ways of doing case study research (e.g. rigorous registration, independent research team) were conceptualized. It becomes increasingly accepted that single case studies provide a necessary method to investigate psychotherapeutic process in their context and in that way provide evidence that can result in clinically relevant knowledge. Different approaches are outlined in the literature to use single case research to boost evidence-based practice in psychology. In this panel we elaborate three specific ways of using single case methodology to study psychotherapy and to aggregate findings from single case research. The first presentation will argue why the dominant nomothetic paradigm fails to capture psychic processes as the mainly correlational group designs reduce the human subject to a static system while we need methods that appreciate its complex and dynamic qualities. Second, a theory-building case study on a case of dissociative identity disorder is presented to illustrate how such a complex and dynamic system can be grasped and how single case studies can elaborate, falsify and refine theory. In a third presentation, it is discussed how the aggregation of several theory-building cases can take a step further in refining theory. Finally, another way to aggregate findings of case study research by means of a meta-study of published cases on depression is presented. Keywords: single case study, complex and dynamic systems, methodology, meta-study Paper in a panel Title: How psychotherapy case studies contribute to practice-based evidence Authors: Mattias Desmet (presenter), Reitske Meganck, Jochem Willemsen, Shana Cornelis Abstract Aim: Contemporary psychological research is more and more confronted with severe methodological problems, such as incapability to replicate findings. This presentation will show that these problems are based on a more fundamental problem at the level of measurement of psychological phenomena. In its turn, this is related to a fundamentally wrong implicit assumption on the nature of psychological phenomena. Specifically, mainstream academic psychology starts from the nomothetic paradigm (i.e. relying heavily on standardized measurement of psychological phenomena in group designs and computing correlations between the different measurements) and conceives psychological phenomena as static systems. Method: A review of the most important findings on validity and reliability of measurement in the nomothetic paradigm and concrete examples form psychotherapy research. Results: The results of empirical research clearly show that psychological phenomena are structured, not as static systems, but as complex and dynamic systems. Discussion: We argue that academic psychology will have to move to research methods adequate to investigate complex and dynamic systems. This inevitably implies a focus on the level of the single case (since, in complex and dynamic systems, it makes no sense to separate a single characteristics from the totality of the system to which it belongs) and focus on narrative and mathematical description instead of quantitative description. Furthermore, implications of the required paradigm shift at the level of academic psychology’s ambition to generalize and to predict will be discussed. Keywords: method, psychotherapy research, case studies, systems theory Paper in a panel Title: Authors: Reitske Meganck (presenter), Mattias Desmet, Ruth Inslegers, Jochem Willemsen, Shana Cornelis Title: A systematic single case study of dissociative identity disorder: memory integration without working with alters? Abstract Aim: Dissociative identity disorder (DID) has always captured fascination, yet remains a highly debated diagnosis. Debate centers on the veracity of the diagnosis. The dominant model considers trauma as a direct etiological factor and proposes a therapeutic model where alter personalities are directly addressed. In this paper we question the necessity of working with alters to facilitate integration Method: A theory-building single case study is proposed where theoretical assumptions concerning interventions addressing integration can be examined in detail. Session transcripts of a successful psychodynamic psychotherapy of a patient with DID will be analyzed using the Consensual Qualitative Research method (Hill, 2012). Results: Detailed analysis of turning points in therapy show that elaborating conflicts and preserving space for the fundamental division of human psychic functioning result in an integration of memory and a disappearance of anxiety and the dissociative episodes. Discussion: We conclude that fine-grained analyses of single cases allow moving beyond general theoretical statements and question taken for granted ideas about effective therapy approaches for specific disorders like DID. The case study illustrates that, at least in this case, working with unconscious conflicts rather than addressing alters dissolved dissociative symptomatology. Keywords: Case study, Dissociative Identity Disorder, theory-building, process Paper in panel Title: Interactions between symptomatic and interpersonal changes during supportive-expressive psychodynamic therapy: Integration of four theorybuilding case studies Author: Shana Cornelis (presenter), Mattias Desmet, Reitske Meganck, Ruth Inslegers Abstract Aim: In contemporary psychotherapy literature, the symptom specificity hypothesis (SSH; Blatt, 2004) claims that specific types of neurotic symptoms are related to specific modes of interpersonal functioning. Yet, findings from crosssectional group studies on symptom specificity don’t converge (Desmet, Vanheule & Verhaeghe, 2006), possibly indicating an underestimation of the complexity of associations. Integrating the findings from four evidence-based, theory-building case studies, this paper aims at refinement of the classical SSH through suggesting complexities. Method: Standardized outcome and process data, and session transcripts from four empirical case studies (different patients, same therapist) were systematically compared with respect to the longitudinal clinical interplay between symptomatic and interpersonal changes throughout supportiveexpressive psychodynamic therapy (Luborsky, 1984). Consensual Qualitative Research for Case Studies (CQR-c, Jackson, Chui, & Hill, 2011) was used as an overarching data-analytic method. Interpersonal functioning was assessed by means of the Core Conflictual Relationship Theme method (Luborsky & CritsCristoph, 1998). Results: For all patients, close associations were observed between interpersonal and symptomatic changes throughout therapy, and psychodynamic interventions focusing on interpersonal dynamics proved effective in reducing symptomatology. Complaints were strongly embedded into disturbing struggles in the interpersonal sphere: bodily symptoms largely covaried with dependent interpersonal styles, for obsessional complaints, strong ambivalences between autonomy and dependency were observed. Discussion: Preliminary results indicate a higher complexity in associations between neurotic symptoms and interpersonal dynamics than predicted by the classical symptom specificity hypothesis, especially for obsessional complaints, suggesting a need for refinement. Conceptual and methodological considerations, limitations and future research indications are discussed. Keywords: multiple case study, theory building, change mechanisms, core conflictual relationship theme, process Paper in a panel Title: A decade of case study research on psychotherapy for depression: A metastudy on the methodology Authors: Jochem Willemsen (presenter), Reitske Meganck, Mattias Desmet, Ruth Inslegers Abstract Aim. Single case research makes an important contribution to the field of psychotherapy research (APA, 2006), but there are huge variations in the methodological quality and evidential value of case studies. In this presentation, we will discuss the results of a meta-method study into the methodological qualities of recent case studies on depression. Methods. A meta-method study (Patterson et al., 2001) is a research approach involving the analysis of methods of previously conducted studies in order to examine methodological presuppositions, evaluate research methods in terms of weakness and limitations, and codify new procedural norms for research in the area. The current meta-method study focuses on case studies of depressive patients, treated with any type of psychotherapeutic approach, and published between 2005 and 2015. Results. The results will be summarized in separate tables for 1) research question, 2) researcher and setting, 3) case selection, 4) data collection. The findings of this study allow us to consider how different case study methodologies have been applied in recent years and how this has influenced the emergent insight in the field: which questions are asked, by whom, how are patients selected, and how are data collected? Discussion. The conclusions will be relevant both for future case studies and for meta-syntheses in which the knowledge gained from individual case studies is synthesised in more generalizable knowledge. Keywords: Case study, depression, meta-study