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NINE ABDOMINOPELVIC REGIONS Maintaining Homeostasis • The body communicates through nervous and endocrine systems consisting of 3 basic components 1) Receptor • Detects a stimulus 2) Control center • Analyzes information • Determines appropriate response 3) Effector (Muscles or glands) • Responds to the stimulus Simple columnar Stratified Squamous Bone Simple squamous Simple Squamous Simple Squamous Nervous Stratified Cuboidal Stratified columnar Stratified columnar Stratified columnar Nerve Simple cuboidal Smooth muscle Skeletal Muscle Cardiac muscle Skeletal muscle Stratified Squamous Skull Thoracic cage (ribs and sternum) Vertebral column Sacrum Cranium Facial bones Clavicle Scapula Sternum Rib Humerus Vertebra Radius Ulna Carpals Phalanges Metacarpals Femur Patella Tibia Fibula (a) Anterior view Tarsals Metatarsals Phalanges Figure 7.1a C1 Cervical curvature (concave) 7 vertebrae, C1–C7 Spinous process Transverse processes Thoracic curvature (convex) 12 vertebrae, T1–T12 Intervertebral discs Intervertebral foramen Lumbar curvature (concave) 5 vertebrae, L1–L5 Sacral curvature (convex) 5 fused vertebrae sacrum Anterior view Coccyx 4 fused vertebrae Right lateral view Figure 7.16 Distal Middle Proximal 1 Medial cuneiform Intermediate cuneiform Navicular Talus Trochlea of talus (a) Superior view 2 3 4 5 Phalanges Metatarsals Lateral cuneiform Cuboid Tarsals Calcaneus Figure 7.33a Phalanges • Distal • Middle • Proximal Sesamoid bones Carpals • Trapezium • Trapezoid • Scaphoid Radius (a) Anterior view of left hand Metacarpals • Head • Shaft • Base Carpals • Hamate • Capitate • Pisiform • Triquetrum • Lunate Ulna Carpals • Trapezium • Trapezoid • Scaphoid Radius (b) Posterior view of left hand Figure 7.28a-b • Gouty Arthritis • Deposition of uric acid crystals in joints and soft tissues, followed by inflammation • More common in men; Typically affects the joint at the base of the great toe • In untreated gouty arthritis, the bone ends fuse and immobilize the joint • Treatment: drugs, plenty of water, avoidance of alcohol • Rheumatoid Arthritis (RA) Chronic, inflammatory, autoimmune disease of unknown cause • Usually arises between age 40 and 50, but may occur at any age; affects 3 times as many women as men • Signs and symptoms include joint pain and swelling (usually bilateral), anemia, osteoporosis, muscle weakness, and cardiovascular problems; RA begins with synovitis of the affected joint • Inflammatory blood cells migrate to the joint, release inflammatory chemicals • Inflamed synovial membrane thickens into a pannus • Pannus erodes cartilage, scar tissue forms, articulating bone ends connect (ankylosis) • Conservative therapy: aspirin, long-term use of antibiotics, and physical therapy • Progressive treatment: anti-inflammatory drugs or immunosuppressants Movements at Synovial Joints 1. Gliding 2. Angular movements: – Flexion, extension, hyperextension – Abduction, adduction – Circumduction 3. Rotation – Medial and lateral rotation Movements at Synovial Joints 4. Special movements – – – – – – Supination, pronation Dorsiflexion, plantar flexion of the foot Inversion, eversion Protraction, retraction Elevation, depression Opposition Gliding Movements • One flat bone surface glides or slips over another similar surface • Examples: – Intercarpal joints – Intertarsal joints – Between articular processes of vertebrae Gliding (a) Gliding movements at the wrist Figure 8.5a Angular Movements Movements that occur along the sagittal plane: • Flexion—decreases the angle of the joint • Extension— increases the angle of the joint • Hyperextension—excessive extension beyond normal range of motion Hyperextension Extension Flexion (b) Angular movements: flexion, extension, and hyperextension of the neck Figure 8.5b Extension Hyperextension Flexion (c) Angular movements: flexion, extension, and hyperextension of the vertebral column Figure 8.5c Flexion Extension Flexion Extension (d) Angular movements: flexion and extension at the shoulder and knee Figure 8.5d Angular Movements Movements that occur along the frontal plane: • Abduction—movement away from the midline • Adduction—movement toward the midline • Circumduction—flexion + abduction + extension + adduction of a limb so as to describe a cone in space Abduction Adduction Circumduction (e) Angular movements: abduction, adduction, and circumduction of the upper limb at the shoulder Figure 8.5e Rotation • The turning of a bone around its own long axis • Examples: – Between C1 and C2 vertebrae – Rotation of humerus and femur Rotation Lateral rotation Medial rotation (f) Rotation of the head, neck, and lower limb Figure 8.5f Special Movements • Movements of radius around ulna: – Supination (turning hand backward) – Pronation (turning hand forward) Pronation (radius rotates over ulna) Supination (radius and ulna are parallel) (a) Pronation (P) and supination (S) Figure 8.6a Special Movements • Movements of the foot: – Dorsiflexion (upward movement) – Plantar flexion (downward movement) Dorsiflexion Dorsiflexion Plantar flexion Plantar flexion (b) Dorsiflexion and plantar flexion Figure 8.6b Special Movements • Movements of the foot: – Inversion (turn sole medially) – Eversion (turn sole laterally) Inversion Eversion (c) Inversion and eversion Figure 8.6c Special Movements • Movements in a transverse plane: – Protraction (anterior movement) – Retraction (posterior movement) Protraction of mandible Retraction of mandible (d) Protraction and retraction Figure 8.6d Special Movements • Elevation (lifting a body part superiorly) • Depression (moving a body part inferiorly) Elevation of mandible Depression of mandible (e) Elevation and depression Figure 8.6e Special Movements • Opposition of the thumb – Movement in the saddle joint so that the thumb touches the tips of the other fingers Opposition (f) Opposition Figure 8.6f • Odor Of Orangutan Terrified Tarzan After Forty Voracious Gorillas Viciously Attacked Him • Old Opie Occasionally Tries Trigonometry And Feels Very Gloomy, Vague And Hypoactive • • • • • • • • • • • • • The cranial nerves are: I - Olfactory nerve II - Optic nerve III - Oculomotor nerve IV - Trochlear nerve V - Trigeminal nerve/dentist nerve VI - Abducens nerve VII - Facial nerve VIII - Vestibulocochlear nerve/Auditory nerve IX - Glossopharyngeal nerve X - Vagus nerve XI - Accessory nerve/Spinal accessory nerve XII - Hypoglossal nerve Precentral gyrus Frontal lobe Central sulcus Postcentral gyrus Parietal lobe Parieto-occipital sulcus (on medial surface of hemisphere) Lateral sulcus Occipital lobe Temporal lobe Transverse cerebral fissure Cerebellum Pons Medulla oblongata Spinal cord Fissure (a deep sulcus) Gyrus Cortex (gray matter) Sulcus White matter (a) Figure 12.6a Frontal lobe Central sulcus Gyri of insula Temporal lobe (pulled down) (b) Figure 12.6b Pineal gland Hypothalamus Pituitary gland Thyroid gland Parathyroid glands (on dorsal aspect of thyroid gland) Thymus Adrenal glands Pancreas Ovary (female) Testis (male) Figure 16.1 Mechanisms of Hormone Action • Two mechanisms, depending on their chemical nature 1. Water-soluble hormones (all amino acid–based hormones except thyroid hormone) • Cannot enter the target cells • Act on plasma membrane receptors • Coupled by G proteins to intracellular second messengers that mediate the target cell’s response Mechanisms of Hormone Action 2. Lipid-soluble hormones (steroid and thyroid hormones) • Act on intracellular receptors that directly activate genes Homeostatic Imbalances of the Brain • Traumatic brain injuries – Concussion—temporary alteration in function – Contusion—permanent damage – Subdural or subarachnoid hemorrhage—may force brain stem through the foramen magnum, resulting in death – Cerebral edema—swelling of the brain associated with traumatic head injury • Alzheimer’s disease (AD): a progressive degenerative disease of the brain that results in dementia; accounts for 50 to 80 percent of dementia cases, early onset types can appear as early as 40 yoa • Two abnormal structures called plaques and tangles are prime suspects in damaging and killing nerve cells. • Plaques are deposits of a protein fragment called beta-amyloid that build up in the spaces between nerve cells. • Tangles are twisted fibers of another protein called tau that build up inside cells. • Transient ischemic attacks (TIAs)— temporary episodes of reversible cerebral ischemia Aorta Superior vena cava Right pulmonary artery Pulmonary trunk Right atrium Right pulmonary veins Fossa ovalis Pectinate muscles Tricuspid valve Right ventricle Chordae tendineae Trabeculae carneae Inferior vena cava Left pulmonary artery Left atrium Left pulmonary veins Mitral (bicuspid) valve Aortic valve Pulmonary valve Left ventricle Papillary muscle Interventricular septum Epicardium Myocardium Endocardium (e) Frontal section Figure 18.4e Body Cavities The ventral cavity contains the thoracic & abdominopelvic cavities, and are separated by the diaphragm. Dorsal cavity contains the cranial and spinal cavities Cerebral hemisphere Septum pellucidum Interthalamic adhesion (intermediate mass of thalamus) Interventricular foramen Anterior commissure Hypothalamus Optic chiasma Pituitary gland Mammillary body Pons Medulla oblongata Corpus callosum Fornix Choroid plexus Thalamus (encloses third ventricle) Posterior commissure Pineal gland (part of epithalamus) Corpora quadrigemina MidCerebral brain aqueduct Arbor vitae (of cerebellum) Fourth ventricle Choroid plexus Cerebellum Spinal cord Figure 12.12 · Premature Ventricular Complexes PVCs Also you'll see 2 odd waveforms, these are the ventricles depolarizing prematurely in response to a signal within the ventricles.(Above - unifocal PVC's as they look alike if they differed in appearance they would be called multifocal PVC's, as below) Multi focal PVCs