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Chapter 5 INTEGUMENTARY SYSTEM FUNCTIONS OF THE SKIN • The skin has 7 functions: 1 - Covers underlying tissues to protect against dehydration, injury, and germ invasion 2 - Regulates body temperature, controlling amount of heat loss. (evaporation) 3 - Helps manufacture vitamin D FUNCTIONS OF THE SKIN 4- Serves as the site of many nerve endings 5- Temporarily stores fat, glucose, water, and salts 6- Screens out ultraviolet radiation 7 -Absorbs certain drugs and chemical substances STRUCTURE OF THE SKIN • Layers of the skin: – Epidermis - the outermost covering of epithelial cells with no blood vessels – Dermis - true skin made of connective tissue and is vascular – Subcutaneous (hypodermal layer) lies under the dermis and consists of loose connective tissue STRUCTURE OF THE SKIN Epidermis • Consists of 4 distinct cell types and five layers • Thickness varies – thinnest on eyelids and thickest on palms of hands and soles of feet Epidermis • Keratin – protein that keeps the skin dry and provides a waterproof covering, resisting evaporation and preventing excess water loss. – Also serves as a barrier against UV light, bacteria, abrasions, and some chemicals. Trivia Trivia • The largest human organ is the skin, which has a surface area averaging ___ square feet. Trivia • The largest human organ is the skin, which has a surface area averaging 25 square feet. Epidermal Cells • Keratinocytes – comprise most of the epidermis and produce the protein keratin • Merkel cells – are the sensory receptors for touch. Epidermal Cells • Melanocytes – make the protein melanin, which protects the skin against the UV rays of the sun. • Langerhans cells – are macrophages which are effective in the defense of the skin against macrophages. Epidermal layers 1 -Stratum germinativum – (AKA stratum basale) – Undergoes continuous cell division (mitosis) – Deepest epidermal layer – Consists of cells that are mostly keratinocytes, can find melanocytes and merkel cells Epidermal layers – Lower edge contains ridges – papillae. • Arise from the dermal layer and push into the str. germ. • Provide max. resistance to slipping when grasping and holding objects. • AKA friction ridges • Fingerprints Epidermal layers • 2 – stratum spinosum – Cells look like have spines (due to fixation preparation) – Contain keratinocytes – Also some melanin granules and Langerhans’ cells – 8-10 cell layers thick Epidermal layers 3- stratum granulosum – 3-5 cell layers of keratinocytes. – Cells are flat – Cells begin to die here due to being so far away from capillaries of dermis Epidermal layers • 4- stratum lucidum – Appears translucent – Consists of a few rows of dead keratinocytes – Only visible on thick skin Epidermal layers • 5- stratum corneum – 10 -30 cell layers thick – Prevents water loss, protection from external environment – Cells are slightly acidic for protection – Can be keratinized or non-keratinized • Keratinized on hands/feet Dermis • Thicker, inner layer of skin • Contains matted masses of connective tissue, collagen tissue bands, elastic fibers, blood vessels, nerve endings, muscles, hair follicles, oil and sweat glands, and fat cells. Sensory Receptors of Dermis 1. Free dendritic nerve endings of sensory neurons – Located in dermis,epithelia, glands – Sense pain, heat and cold, and pressure 2. Merkel discs – At base of epidermis of skin – Sense light pressure Sensory Receptors of Dermis 3. Root hair plexuses -In and surrounding hair follicles -Feel hair deflection 4. Meissner’s corpuscles -Dermal papillae of hairless skin – lips, eyelids, nipples, fingertips -Light pressure, vibration Sensory Receptors of Dermis 5. Pacinian corpuscles -Subcutaneous tissue of skin -Deep pressure, stretch, vibration Pop Quiz 1. What are the layers of the skin, in order from outside world inward? 2. What are the 3 main types of fingerprints? 3. What types of tissues can be found in a skin sample? TRIVIA Trivia • Based on the selling price of cowhide, which is approximately $.25 per square foot, the value of an average person’s skin is about ________. Trivia • Based on the selling price of cowhide, which is approximately $.25 per square foot, the value of an average person’s skin is about $6.25. Subcutaneous layer • • • • Aka hypodermal layer Lies under the dermis Not a true part of the IS Consists of loose connective tissue and contains about ½ of the body’s stored fat. • Attaches IS to the surface muscles underneath. • Injections – hypodermic or subcutaneous (subcu) Pop Quiz 1. What are the 4 cells types found in the epidermis? 2. What is another name for the subcutaneous layer of the skin? 3. Name the layers of the skin from inner to outermost. 4. What is the white part of hair called?