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Chapter 6 The Integumentary System Three Types of Epithelial Membranes • Serous Membranes – Line cavities and cover organs – Simple squamous epithelium over loose connective tissue – Parietal and visceral portions – Secrete a serous (watery) fluid for lubrication Three Types of Epithelial Membranes • Mucous membranes – Line cavities that open to the exterior – Layer of epithelium over connective tissue; epithelium varies with location – Tight junctions and goblet cells • Cutaneous membrane is the skin – the major organ of the integumentary system Integumentery System A. Parts include • the skin and the organs derived from it (hair, glands, nails, specialized receptors) • One of the largest organs – 2 square meters; 10-11 lbs. – Largest sense organ in the body • The study of the skin is Dermatology. Integumentary System B. Considered an organ system because . . . • Organs are two or more tissues which together perform a specialized function. QuickTime™ and a Sorenson Video 3 decompressor are needed to see this picture. What are some functions of the integumentary system? Brainstorming time! Functions include: 1. Protection (immunity) - physical barrier to environment physical abrasion dehydration ultraviolet radiation 2. Sensation/sensory - responds to stimuli touch vibration pain temperature Functions include: 3. Regulation of body temperature – Cellular metabolism produces heat as a waste product. – High temperature • Dilate surface blood vessels • Sweating – Low temperature • Surface vessels constrict • shivering Functions include: 4. Excretion of wastes (perspiration) 5. Synthesis of vitamin D stimulated by ultraviolet light aids absorption of calcium 6. Prevent water loss - “impermeable” barrier QuickTime™ and a Sorenson Video 3 decompressor are needed to see this picture. Layers of the Skin D. Layers of the Skin include Two main layers Epidermis* Dermis Subcutaneous layer or hypodermis * Determines thickness of skin Layers of the Skin E. Epidermis 1. tissue type(s) 2. 4 types of cells 3. Thickness of the skin 4. Layers of the epidermis (bottom to top) Layers of the Epidermis • Stratum basale (stratum germinativum) – Single layer of living cells – Continuous cell division – produce keratinocytes – Melanocytes - # the same for all races • Melanin produced in melanocytes Layers of the Epidermis • Stratum spinosum (spiny) – 8-10 layers of living cells – Function is support – Keratinocytes take in melanin by cytocrine secretion Layers of the Epidermis • Stratum granulosum – 3-5 layers – Keratinization begins here – Cells beginning to die, nuclei still present Layers of the Epidermis • Stratum lucidum * (lucid = clear) – More apparent in thick skin – 3-5 layers of clear dead cells – Eleidin *Only found in palms & soles Layers of the Epidermis Stratum corneum (horny layer) – Dead, flat cells full of keratin – Keratin is waterproof – Cells are shed continuously • Basal cell to surface – about 2-4 weeks Layers of the Epidermis Mnemonic devices??? Canadian ladies give superb backrubs. Can little girls speak German? Can Lauren get some booty? The Dermis F. Dermis 1. Tissue types - Connective tissue with collagen and elastic fibers,also has nerves, blood vessels, muscle fibers, hair follicles and glands The Dermis F. Dermis 2. Papillary layer – Top 1/5 of dermis – loose connective tissue – Highly vascular – Dermal papillae - fingerprint patterns – Functions of papillae The Dermis F. Dermis 3. Dermatoglyphics QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. The Dermis 4. Reticular (net) layer (bottom 4/5) – Dense irregular connective tissue – Sebaceous (oil) glands – Hair follicles – Ducts of sudoriferous (sweat) glands – Striae or stretch marks – Functions Subcutaneous Layer (Hypodermis) G. Subcutaneous layer 1. Tissue types 2. Types of fibers 3. Functions 4. Changes during lifetime Skin color • Genetic factors - most important • Melanin, carotene, & blood vessels – Everyone has the same number of melanocytes – Difference is how much melanin is made • Environmental factors – UV light or x-rays Albinism - albinos QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. Skin Color • Melanin is made in melanocytes • S. basale and s. spinosum • Melanin absorbed via cytocrine secretion/phagocytosis • Carotene found in s. corneum and fatty areas of dermis • Caucasians have less melanin & carotene in epidermis QuickTime™ and a Sorenson Video 3 decompressor are needed to see this picture. Accessory Organs • Hair (pili) – Dead epidermal cells – Function in protection • Scalp hair - sun (UV radiation) • Eyebrows & eyelashes • Nose & ear – Touch The Strength of Hair QuickTime™ and a decompressor are needed to see this picture. The Strength of Hair QuickTime™ and a decompressor are needed to see this picture. Accessory Organs Hair Structure Shaft, root, and follicle 3 parts of shaft (outside to middle) cuticle cortex* medulla* Root has same 3 parts. * = contains pigment Accessory Organs Hair Hair follicle - tube-like depression at base of hair Surrounds root Downgrowth of epidermis in third month of fetal development, then hair grows to surface- inside the follicle Accessory Organs Hair Bulb - enlarged area at bottom of hair; contains papilla Papilla - contains capillaries that nourish hair Accessory Organs Hair – Sebaceous glands keep hair from drying out – Arrector pili muscle (goose bumps) – Hair growth and replacement have a cyclical pattern – ‘male-pattern’ baldness (genetics/inherited) – Hair color - genes control type and amount of pigment deposited Going Gray QuickTime™ and a Sorenson Video 3 decompressor are needed to see this picture. Alopecia QuickTime™ and a Sorenson Video 3 decompressor are needed to see this picture. Nails • Plates of highly packed, keratinized cells • Functions - protection, gripping, grasping & manipulation • Formed by epidermal cells in nail bed called the matrix • 1 mm / week Nail Growth going to extremes QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. World's Longest Fingernails Lee Redmond, a 66-year-old great grandmother from Utah, currently holds the Guinness World Record for longest fingernails. Nails • Parts of a nail: – Nail body - the nail itself – Free edge - distal end, white due to no tissue underneath – Nail root - nail growth, under the skin – Nail matrix - responsible for nail formation – Nail bed - tissue under nail, light pink due to tissue underneath Nails • Parts of a nail: – Lunula - “half moon” at proximal end of nail; area of most rapid growth – Eponychium- thickened stratum corneum at proximal end of nail; known as the cuticle – Hyponychium - thickened stratum corneum underneath nail End of Part 1 of the Integumentary System