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Nervous Control of Respiration • Dorsal Group of Neurons • Ventral Group of Neurons • Pneumotaxic Center • Apneustic Center Respiratory Control centers in the Brain Stem Respiratory control centers Dorsal Respiratory Group • Generation of basic rhythm of respiration i.e. Ramp Signal • Neurons are located with in the nucleus of tractus solitarius • Role of Pre botzinger complex Schematic representation of medullary dorsal respiratory group (DRG) control of inspration Ventral respiratory group of Neurons • Neurons are located in the mucleus ambiguus rostrally and the nucleus retroambiguus caudally • Remains totally in active during normal quiet respiration • Provide powerful expiratory signals to the abdominal muscles during very heavy expiration Pneumotaxic Center • Neurons are located dorsally in the nucleus parabrachialis of the upper pons • Transmit signal to the dorsal respiratory group • • It controls the “switch-off ” point of the inspiratory ramp It primarily limits inspiration Apneustic Center • Is situated in the lower part of pons • Sends signals to dorsal respiratory group of neurons to prevent the “Switch-off” of the inspiratory ramp signal. • Controls intensity of inspiration