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CHAPTER 19 NERVOUS SYSTEM Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 1 Chapter 19 Learning Objectives Define at least 10 terms relating to the nervous system. Describe the function of the nervous system. Identify at least 10 structures of the nervous system. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 2 Chapter 19 Learning Objectives Identify at least three methods used to assess the function of the nervous system. Describe at least five disorders of the nervous system. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 3 Structure and Function The nervous system is divided into two major parts: Central nervous system (CNS) Peripheral nervous system (PNS) The nervous system senses, interprets, and responds to internal and external environmental changes to maintain the body’s homeostasis. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 4 Central Nervous System Parts of the CNS Brain Spinal cord Coordinates body’s full nervous system Contains nerves that control connections between impulses to and from the brain and the rest of the body Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 5 Central Nervous System The CNS plays a critical role in maintaining a healthy, normally functioning body. Meninges (tough membranes) protect the nervous tissues. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 6 Central Nervous System FIGURE 19-1 Divisions of the nervous system. A, The central nervous system. (From Sorrentino SA: Mosby’s textbook for nursing assistants, ed 7, St. Louis, 2008, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 7 Peripheral Nervous System The PNS contains 12 pairs of cranial nerves • Originate in the brain 31 pairs of spinal nerves • Act independently from the brain in some reflex reactions Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 8 Peripheral Nervous System FIGURE 19-1 Divisions of the nervous system. B, The peripheral nervous system. (From Sorrentino SA: Mosby’s textbook for nursing assistants, ed 7, St. Louis, 2008, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 9 Functions of the Peripheral Nervous System Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 10 Organs of the Peripheral Nervous System PNS organs contain Afferent (sensory) neurons • Carry messages from the sensory cell of the body to the brain Efferent (motor) neurons • Carry messages from the brain to the body organs or parts • Classified as somatic (voluntary) or automatic (involuntary) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 11 Divisions of the Nervous System FIGURE 19-5 The nervous system may be divided into parts on the basis of their functions. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 12 Spinal Reflex Arc FIGURE 19-3 The spinal reflex arc. The motor response to injury is a reflex action controlled by the spinal nerves. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 13 Neurons The basic structural unit of the nervous system is the nerve. A nerve is a bundle of fibers that carries impulses (messages) to and from the body’s organs. Nerve fibers consist of neurons (cells). Three main types of neurons • Afferent (sensory) • Efferent (motor) • Interneuron Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 14 Autonomic Nervous System Sympathetic system Sympathetic nerves are stimulated in situations that require action (e.g., fight-or-flight reaction). Parasympathetic system Parasympathetic nerves respond to normal, everyday situations. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 15 Neurons Important parts of a neuron Dendrites • Receive impulses and transmits them to the cell body Cell body • Transmits impulses to the axon Axon • Transmits impulse away from the cell body to the dendrite of the next neuron Myelin (white matter) • White, fatty substance covering the axon • Arranged in bundles called Schwann cells Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 16 Neurons FIGURE 19-6 Neuron. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 17 Glia Special nervous tissue cells that act as “glue” to support, bind, repair, and protect neurons Five major types Astrocyte cells Oligodendroglia Microglia Ependymal cells Neuroglia Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 18 Synapse Space between two neurons Impulses from one neuron are transmitted across the synapse to another neuron by a chemical called a neurotransmitter. Most common neurotransmitters Acetylcholine Norepinephrine Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 19 Ganglia Groups of nerve cell bodies Located outside of the CNS Increased ability to transmit impulses because they are clustered in the ganglion Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 20 Plexus and Dermatome Plexus Four major networks of interwoven spinal nerves • • • • Cervical Brachial Lumbar Sacral Provides impulses to specific regions of the body Dermatomes Spinal nerves that control sensations on the skin surface Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 21 Brain Largest structure of the nervous system and one of the largest organs of the body Weighs 2 to 3 pounds Covered by three layers of membranes called meninges Dura mater Arachnoid Pia mater Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 22 The Brain FIGURE 19-8 The parts of the brain. (From Patton KT, Thibodeau GA: Anatomy & physiology, ed 7, St. Louis, 2010, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 23 Parts of the Brain FIGURE 19-8 The parts of the brain. (From Patton KT, Thibodeau GA: Anatomy & physiology, ed 7, St. Louis, 2010, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 24 Functions of the Brain Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 25 Assessment Techniques Evaluation of the nervous system includes assessment of the following: Mental status Cranial nerve function Motor and sensory nerve function Reflexes Coordination Gait (walking) Balance Internal body processes Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 26 Assessment Techniques Electroencephalography (EEG) Lumbar puncture Myelography Nerve conduction velocity Computed tomography (CT) Positron emission tomography (PET) Magnetic resonance imaging (MRI) Magnetic resonance angiography (MRA) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 27 Electroencephalogram Showing Waves FIGURE 19-9 A, Electroencephalogram showing wave types. (From Thibodeau GA, Patton KT: Human body in health and disease, ed 5, St Louis, 2010, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 28 Scalp Electrodes FIGURE 19-9 B, Scalp electrodes detect electrical voltage changes in the cranium. (From Thibodeau GA, Patton KT: Human body in health and disease, ed 5, St Louis, 2010, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 29 Magnetic Resonance Imaging FIGURE 19-10 Magnetic resonance imagery allows the visualization of the body without use of radiation. (From Elkin MK, et al: Nursing intervention and clinical skills, ed 4, St. Louis, 2008, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 30 Disorders of the Nervous System Alzheimer’s disease Cerebrovascular accident (CVA) Form of senile dementia Commonly called a stroke, it is caused by loss of oxygen to an area of the brain when a clot blocks a vessel or when a vessel breaks. Down syndrome Genetic disorder caused by the presence of an extra chromosome Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 31 Warning Signs of Alzheimer’s Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 32 Disorders of the Nervous System Encephalitis Guillain-Barré syndrome Inflammation of the brain caused by a viral or bacterial infection or by a chemical agent Also called infectious polyneuritis, it may appear shortly after a viral immunization or infection Headache The muscles around the occipital area of the brain constrict the blood flow to the area. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 33 Disorders of the Nervous System Migraine headaches Sinus headaches Vascular headaches of unknown cause Pain results from narrowing of blood vessels in the brain Caused by swelling of the membranes that line the sinus cavities Head injury Occurs when the brain impacts the skull as a result of a blow or rapid movement Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 34 Disorders of the Nervous System Huntington’s chorea Degenerative neural disorder that affects brain tissues Hydrocephalus More cerebrospinal fluid is produced than is absorbed into the circulatory system. Excess fluid increases intracranial pressure and may enlarge the head. Intracranial tumors Usually involve neuroglia, blood vessels, or membranes rather than neurons Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 35 Disorders of the Nervous System Meningitis Meningocele Serious inflammation of the meninges caused by a bacterium, virus, or fungus Birth defect that occurs when the membranes covering the brain or spinal cord protrude through a congenital defect in the skull or spinal column Multiple sclerosis Defect in electrical transmission of the neurons caused by degeneration of the myelin sheath Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 36 Disorders of the Nervous System Neural tube defect Neurofibromatosis Abnormal formation of the skull and spinal column Defect in an autosomal dominant gene Parkinson’s disease Degeneration of certain brain cells Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 37 Tumors of Nervous System Tissue FIGURE 19-12 Tumors of nervous system tissue develop with neurofibromatosis. (From Patton KT, Thibodeau GA: Anatomy & physiology, ed 7, St. Louis, 2010, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 38 Signs of Parkinsonism FIGURE 19-13 The signs of Parkinsonism include rigidity and trembling of the head and extremities. (From Thibodeau GA, Patton KT: Human body in health and disease, ed 4, St Louis, 2005, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 39 Disorders of the Nervous System Poliomyelitis Sciatica Caused by a virus that spreads from the nose and throat to neural tissue Usually a ruptured intervertebral disk and osteoarthritis, producing pressure on the nerve or other nerve injury Seizure Results from injury, infection, or epilepsy Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 40 Disorders of the Nervous System Spina bifida Birth defect involving a malformed spinal column resulting from neural tube defects Spinal cord injuries Trauma occurring in the cervical and lumbar area of the spinal column Transient ischemic attack (TIA) Decreased blood supply to an area of the brain resulting from a small clot that temporarily lodges in a vessel Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 41 Disorders of the Nervous System Trigeminal neuralgia Sudden, intense, unpredictable pain on one side of the face caused by pressure on or deterioration of the trigeminal facial nerve Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 42 Trigeminal Neuralgia FIGURE 19-14 One method used to relieve the pain of trigeminal neuralgia is surgically to remove the ganglion on the end of the nerve. (From Patton KT, Thibodeau GA: Anatomy & physiology, ed 7, St. Louis, 2010, Mosby.) Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 43 Issues and Innovations Memory research Memories are retained differently and in different parts of the brain. Ribonucleic acid (RNA) may play a role in storing and recalling information. Most memory research uses a marine slug called Aplysia or people who have sustained neurologic loss • Slugs are used because their ganglia are large and their behavior pattern is limited. Computer networks are being designed to simulate actions of the brain. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 44 Issues and Innovations Correction of Parkinson’s disease Transplantation of adrenal cells to stimulate production of dopamine Fetal tissue research Deep brain stimulation Autologous neural stem cell transplantation Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 45 Summary The function of the nervous system is to sense, interpret, and respond to internal and external environmental changes to maintain homeostasis. Structures of the nervous system include the CNS and PNS and their parts. Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 46 Summary Methods of assessment of the nervous system EEG Lumbar puncture Myelography CT PET Copyright © 2012, 2007, 2003, 1997, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. 47