Download Syllabus - Dr. Chen

Developmental Biology
Cell 4160/6160
Fall, 2015
Instructor: Dr. YiPing Chen
Office Rm: 4036 Stern Hall
Lecture: T. Th.: 9:30 – 10:45 AM
Office Hour: 11:00AM – 12:00PM, T.TH.
Phone: 247-1593
Email: [email protected]
Textbook: “Developmental Biology” By Scott Gilbert, 10th Edition, Sinauer Associates, Inc
Course description (Undergraduates enrolled in Cell 416/Graduate students enrolled in Cell
616): Vertebrate animal development is discussed in a lecture style, with focus on initiation and
construction of an organism and the underlying molecular and genetic basis.
Course objectives: Students will acquire fundamental knowledge of animal embryonic
development--that is how an egg develops into an adult. Students will also learn how genes
function to control phenotype of an organism. Graduate students are required to take extra work
to meet the requirement, such as discussion and presentation of related-literatures. Students will
be prepared for more advanced course in developmental biology such as “Cell 478/678Developmental Genetics” in CMB or other related courses in graduate/professional schools. For
graduate students, the course will also provide them basic developmental biology concepts that
are essential for other graduate-level cell and developmental biology courses and for their
research in developmental biology field.
Learning outcomes:
1.
2.
3.
4.
5.
6.
7.
Understand and master basic concepts of developmental biology
Understand how fertilization and cleavage occur
Understand the process and consequence of gastrulation
Understand mesoderm induction and neural induction
Understand basic concepts of organogenesis
Understand basic concepts of growth, regeneration and aging
Understand basic concepts of gene expression and regulation
Course Schedule:
Date
Lecture Topics
Reading
8/25
8/27
9/1
9/3
9/8
9/10
9/15
9/17
9/22
9/24
Introduction: an overview of animal development
Basic concepts of embryogenesis
Structures of gene, promoter and enhancer
Transcription factors
Growth factors
Regulation of differential gene expression
Gamete
Fertilization
Review
Exam I
Chapter 1
Chapter 1, Part II
Chapter 2
Chapter 2
Chapter 3
Chapter 2
Chapter 4
Chapter 4
9/29
10/1
10/6
10/8
10/13
10/15
10/20
10/22
10/27
10/29
11/3
Cleavage and Gastrulation
Mesoderm induction (I)
Mesoderm induction (II)
No class
Neurulation
Fall Break
Neural induction
Neural crest cells
Somite formation and patterning
Review
Exam II
Chapters 5, 7, 8, 9
Chapter 7, 8,
Chapter 7,8
11/5
11/10
11/12
11/17
11/19
11/24
11/26
12/1
12/3
Hox gene
Vertebrate limb development (I)
Vertebrate limb development (II)
Growth
Regeneration
Aging
Thanksgiving Break
Review
Final Exam
Chapter 9
Chapter 14
Chapter 14
Chapter 16
Chapter 16
Chapter 16
Chapter 10
Chapter 8, 10
Chapter 11
Chapter 12
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