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Applications of LASERs 3MOLS 23/11/01 University of Surrey Jeremy Allam School of Physics and Chemistry Optoelectronic Devices and Materials Research Group Guildford, Surrey GU2 7XH, UK Tel +44 (0)1483 876799 Fax +44 (0)1483 876781 Applications of lasers 1. General lasers • coherent • monochromatic 2. High power lasers • high CW power • high pulsed powers • Interferometry • Holography • material processing • medical applications • nuclear fusion 3. ‘Ultrafast’ lasers • short pulses (<5fs) • broadband gain(>300nm) • high peak powers (>TW) • dynamics of physical, chemical, biological processes • spectroscopy, pulse shaping • high energy processes, wavelength conversion Longitudinal Coherence of Laser Light leads to phase noise or drift (spontaneous emission, temperature drift, microphonics, etc) finite spectral width L phasor at t=0 phasor at t=t1 leads to finite coherence time tc (or length lc) 1 tc lc c t c Dn L tc (or lc) Measuring Longitudinal Coherence use interferometer e.g. Michelson interferometer M1 M1 L1 BS M2 for long coherence lengths, use optical fibre delay L1 optical BS fibre L2 detector detector (path length) = 2L1-2L2 << coherence length lc output output 2L1-2L2 ~ lc 0 0 L 1 L 1 M2 Applications of interferometers {see Smith and King ch. 11} Measurement of length: LINEAR TRANSLATION: interferometric translation stage FLATNESS/UNIFORMITY: e.g. Twyman-Green interferometer LINEAR VELOCITY OF LIGHT: famous Michelson-Morley experiment c is independent of motion of reference frame DETECTING GRAVITATIONAL WAVES: minute movement of end mirrors ROTATION (e.g. of earth): Sagnac interferometer as an optical gyroscope: For N loops of area A and rotation rate W, phase difference is: fS 8pWNA lc Measurement of optical properties: REFRACTIVE INDEX: Rayleigh refractometer LIGHT SCATTERING: heterodyne spectrometry ULTRAFAST DYNAMICS: pump-probe / coherent spectroscopy Numerous other applications... Holography RECORDING {see Smith and King ch. 19} READING / RECONSTRUCTING Photography - record electric field intensity of light scattered by object illuminating beam photograph object 2D representation of image (no depth) eye photographic plate Holography - record electric field intensity and phase reference beam beam expander illuminating beam LASER BS Hologram (photographic plate) object reconstruction beam hologram reconstructed image diffracted reference beam eye Laser fabrication of Be components http://www-cms.llnl.gov/wfo/laserfab_folder/index.html a high-speed, low-cost method of cutting beryllium materials No dust problem (Be dust is poisonous) autogenous welding is possible Achieved using a 400-W pulsed Nd-YAG laser and a 1000-W CW CO2 laser Narrow cut width yields less Be waste for disposal No machining damage Laser cutting is easily and precisely controlled by computer 1kW Nd:YAG cutting metal sheet Laser Tissue Welding Photograph of the laser delivery handpiece with a hollow fiber for sensing temperature. The surgeon is repairing a 1 cm-long arteriotomy. http://lasers.llnl.gov/mtp/tissue.html Laser tissue welding uses laser energy to activate photothermal bonds and/or photochemical bonds. Lasers are used because they provide the ability to accurately control the volume of tissue that is exposed to the activating energy. Nuclear Fusion: National Ignition Facility http://www.llnl.gov/str/Powell.html Why femtosecond lasers? (Titanium-sapphire properties) 1 2 3 ultrashort pulses (5fs) • timing physical processes • time-of-flight resolution broadband gain (700-1000nm) high power (TW) THz pulse generation • pulse shaping • coherent control generate: • UV • X-rays, • relativistic electrons parametric conversion Coherent control of chemical pathways Spectral-domain pulse shaping: Coherently-controlled multi-photon ionisation: Imaging using femtosecond light pulses Nonlinear imaging for 3D sectioning (e.g. TPA fluorescence) femtosecond pulse detection region of TPA Time-resolved imaging for scattering media ‘snake’ photons ballistic photons time diffusive photons early photons scattering medium Why femtosecond lasers in biology and medicine? Conventional laser applications Benefits by using femtosecond lasers ablation • more controllable • less damage spectroscopy • wide spectral range • coherent control imaging • nonlinear imaging (e.g. TPA, THG) ->3D optical sectioning -> contrast in transparent samples • time-of-flight resolution: early photons in diffusive media • THz imaging Ablation with femtosecond lasers Conventional lasers (high average power) Femtosecond lasers (high peak, low av. power) • dominated by thermal processes (burning, coagulation), and acoustic damage • dominated by non-thermal processes (‘photodisruption’) • collateral damage (cut cauterised) • little collateral damage (cut bleeds) • absorption within illuminated region • strong NL effects only at focus (-> sub-surface surgery) • stochastic -> uncontrolled ablation • deterministic -> predictable ablation * due to dynamics of photoionisation (by light field or by multiphoton absorption) and subsequent avalanche ionisation Femtosecond vs. picosecond laser ablation deterministic -> predictable ablation stochastic -> uncontrolled ablation Ultra Short Pulse Laser for Medical Applications -1 http://lasers.llnl.gov/mtp/ultra.html Using ultra-short duration bursts of laser energy, surface material is removed without any significant transfer of energy to the surrounding areas. For laser pulses less than about 10 ps (1/100th of a billionth of a second), we can cut without collateral damage to surrounding tissues. Tiny cuts with amazingly small kerf (>100 um) are produced, without thermal or mechanical damage to surrounding areas. Histological section of a pig myocardium drilled by an excimer laser, illustrating extensive thermal damage surrounding the hole. Histological section of a pig myocardium drilled by an USPL showing a smooth-sided hole free of thermal damage to surrounding tissue. Ultra Short Pulse Laser for Medical Applications -2 http://lasers.llnl.gov/mtp/ultra.html Extensive thermal damage and cracking to tooth enamel caused by 1-ns laser ablation. Smooth hole with no thermal damage after drilling with a USPL. Femtosecond laser surgery of cornea - 1 Femtosecond LASIK Femtosecond interstroma Femtosecond laser surgery of cornea - 2 Lenticle removal using Femtosecond LASIK