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Chapter 7: The Muscular System Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Types of Muscle Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Skeletal Muscle Has Three Primary Functions: • Skeletal movement • Posture maintenance • Heat generation Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Muscle Structure • Fascicles – Bundles of muscle cells (fibers) that make up a whole muscle • Connective tissue – Hold fascicles and whole muscle together – Three layers • Endomysium • Perimysium • Epimysium • Tendons Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Muscle Cells in Action • Motor unit: A single neuron and all the muscle fibers it stimulates – Small motor units used for fine movements – Large motor units used for broad movements Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Muscle Cells in Action • Neuromuscular junction (NMJ): The point at which a nerve fiber contacts a muscle fiber – A type of synapse – NMJ anatomy • Motor neuron • Neurotransmitter (acetylcholine; ACh) • Motor end plate (on muscle fiber) Contains acetylcholine receptors Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Muscle Cells in Action • NMJ allows motor neuron to stimulate muscle fiber to become electrically excited (action potential) • Action potential stimulates muscle contraction • Events at the NMJ – Ach is released from motor neuron into synaptic cleft – Ach diffuses across synaptic cleft towards motor end plate – Ach binds to receptors on motor end plate and stimulates action potential Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Muscle Cells in Action • The sarcomere is the functional unit of contraction in the skeletal muscle fiber • Sarcomere anatomy: – Thick filaments (myosin) – Thin filaments (actin) – Regulatory proteins • Troponin • Tropomyosin Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Muscle Cells in Action •Sarcomeres contract via the sliding filament mechanism: – Myosin heads bind to actin, forming cross-bridges – Using stored energy, myosin heads pull actin filaments together within the sarcomeres and the cell shortens – New ATP is used to detach myosin heads and move them back into position for another “power stroke” Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Figure 7-4 Sliding filament mechanism of skeletal muscle contraction. Sliding filament mechanism of skeletal muscle contraction. Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Muscle Cells in Action • Calcium regulates sarcomeric contraction within the muscle cell: – Action potential from NMJ travels to sarcoplasmic reticulum (SR) – SR releases calcium into cytoplasm – Calcium shifts troponin and tropomyosin off of thin filament soit blocks the sites on actin filaments where cross-bridges form – Muscle relaxes when stimulation ends and calcium is pumped back into SR Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Summary of Events in a Muscle Contraction 1. ACh is released from neuron ending into synaptic cleft at NMJ 2. ACh binds to motor end plate and produces action potential 3. Action potential travels to sarcoplasmic reticulum (SR) 4. SR releases calcium into cytoplasm 5. Calcium shifts troponin and tropomyosin so that binding sites on actin are exposed Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Summary of Events in a Muscle Contraction (continued) 6.Myosin heads bind to actin, forming cross-bridges 7.Using stored energy, myosin heads pull actin filaments together within sarcomeres and cell shortens 8.New ATP is used to detach myosin heads and move them back to position for another “power stroke” 9.Muscle relaxes when stimulation ends and calcium is pumped back into SR Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Energy Sources • Muscle contraction requires ATP • Skeletal muscle prefers to produces ATP via aerobic metabolism, which requires – Oxygen – Glucose • Storage compounds ensure an adequate supply of oxygen and glucose for aerobic ATP metabolism – Myoglobin • Stores additional oxygen, located in muscle cells – Glycogen Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Energy Sources • During strenuous activity, muscle cells use anaerobic ATP metabolism which causes an oxygen debt and does not require ATP – Breakdown of creatine phosphate – Anaerobic glycolysis • Lactic acid accumulation and oxygen debt • Excess postexercise oxygen consumption – After strenuous exercise, person takes in extra oxygen (via rapid breathing) to remove lactic acid and replenish energy stores Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Effects of Exercise • Improved balance, joint flexibility • Increased muscle size (hypertrophy) • Improved muscle tissue • Vasodilation • Strengthened heart muscle • Improved breathing and respiratory efficiency • Weight control • Stronger bones Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Muscular System Types of Muscle Contractions • Partial (muscle tone or tonus) – Partially contracted state that is normal • Isotonic – No change in tension – Muscle length shortens – Movement • Isometric – Great increase in tension – Muscle length unchanged – No movement Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Mechanics of Muscle Movement • Tendons attach muscles to bones. – Origin: Attached to more fixed part of skeleton – Insertion: Attached to more movable part of skeleton Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Figure 7-6 Muscle attachments to bones. Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Mechanics of Muscle Movement Muscles Work Together • Many muscles function in pairs – Prime movers • Movement by a muscle – Antagonists • Produces opposite movment – Synergists • helpers Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body The Mechanics of Muscle Movement Levers and Body Mechanics •Musculoskeletal system as a lever system – Lever—bone – Fulcrum—joint – Force—applied by muscle •Three classes of levers – First class – Second class – Third class—most body systems Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Skeletal Muscle Groups Characteristics for Naming Muscles Characteristic Example Location Temporalis; near the skull’s temple Size Gluteus maximus; the largest Shape Serratus anterior; serrated edge Direction External oblique; runs obliquely Number of heads Biceps brachii; two heads Action Flexor digitorum; flexes toes Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Skeletal Muscle Groups Muscles of the Head and Neck Name Location Function Orbicularis oculi Encircles eyelid Closes eye Levator palpebrae superioris Posterior orbit to upper eyelid Opens eye Orbicularis oris Encircles mouth Closes lips* Buccinator Fleshy part of cheek Flattens cheek; helps in eating, whistling, and blowing wind instruments Temporalis Above and near ear Masseter At angle of jaw Sternocleidomastoid Along lateral neck, to mastoid process Closes jaw Closes jaw-used for chewing* Flexes head; rotates head toward opposite side from muscle, moves head* Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Figure 7-10 Muscles of the head and neck. Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Skeletal Muscle Groups Muscles That Move the Shoulder and Arm Name Location Function Trapezius Posterior neck and upper back to clavicle and scapula Raises shoulder and pulls it back; superior portion extends and turns head Latissimus dorsi Middle and lower back, to humerus Extends and adducts arm Pectoralis major Superior, anterior chest, Flexes and adducts arm to humerus Serratus anterior Inferior to axilla on lateral chest Moves shoulder forward; aids in raising arms, punching, or reaching forward Deltoid Abducts arm; flexes and extends arm Covers shoulder joint, to lateral humerus Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Skeletal Muscle Groups Muscles That Move the Forearm and Hand Name Location Function Biceps brachii Anterior arm along humerus, to radius Flexes forearm; supinates forearm and hand Brachialis Deep to biceps brachii; inserts at anterior elbow joint Forceful flexor of forearm Brachioradialis Lateral forearm from distal end of humerus Flexes forearm Triceps brachii Posterior arm, to ulna Extends forearm Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Skeletal Muscle Groups Muscles That Move the Forearm and Hand (continued) Name Location Function Flexor carpi group Anterior forearm, to hand Flexes hand Extensor carpi group Posterior forearm, to hand Extends hand Flexor digitorum group Anterior forearm to fingers Flexes fingers Extensor digitorum group Posterior forearm to fingers Extends fingers Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Figure 711 Muscles that move the forearm and hand. Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Skeletal Muscle Groups Muscles of the Trunk Name Location Function Diaphragm Dome-shaped partition between thoracic and abdominal cavities Dome descends to enlarge thoracic cavity from top to bottom Intercostals Between ribs Elevate ribs and enlarge thoracic cavity Muscles of abdominal wall: • External oblique • Internal oblique • Transversus abdominus • Rectus abdominis Anterolateral abdominal wall Compress abdominal cavity and expel substances from the body; flex spinal column Levator ani Pelvic floor Aids defecation Erector spinae Group of deep vertical muscles between sacrum and skull Extends vertebral column to produce erect posture Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Figure 7-12 Muscles of respiration. Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Figure 7-13 Muscles of the abdominal wall. Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Skeletal Muscle Groups Muscles That Move the Leg and Thigh Name Location Function Gluteus maximus Superficial buttock, to femur Extends thigh Gluteus medius Deep buttock, to femur Abducts thigh Iliopsoas Crosses anterior hip joint, to femur Flexes thigh Adductor group Medial thigh, to femur Adducts thigh Sartorius Crosses anterior thigh from ilium to medial tibia Flexes thigh and leg (to sit cross-legged) Gracilis Pubic bone to medial surface of tibia Adducts thigh at hip; flexes Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Skeletal Muscle Groups Muscles That Move the Leg and Thigh (continued) Name Location Function Quadriceps femoris • Rectus femoris • Vastus medialis • Vastus lateralis • Vastus intermedius Anterior thigh, to tibia Extends leg Hamstring group • Biceps femori • Semimembranosus • Semitendinosus Posterior thigh; ischium and femur to tibia and fibula Flexes leg at knee; extends and rotates thigh at hip Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Figure 7-15 Muscles of the thigh. How many muscles make up the quadriceps femoris? Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Skeletal Muscle Groups Muscles That Move the Foot Name Location Function Gastrocnemius Posterior leg, to calcaneus, inserting by the Achilles tendon Plantar flexes foot Soleus Posterior leg deep to gastrocnemius Plantar flexes foot Tibialis anterior Anterior and lateral leg, to foot Dorsiflexes and inverts foot Fibularis longus Lateral leg, to foot Everts foot Flexor digitorum group Posterior leg and foot to inferior surface of phalanges Flexes toes Extensor digitorum group Anterior surface of leg bones to superior surface of phalanges Extends toes Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Figure 7-16 Muscles that move the foot. Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Taylor: Structure and Function of the Human Body Effects of Aging on Muscles • Beginning at about age 40 • Gradual loss of muscle cells • Loss of power • Tendency to flex hips and knees • Decrease in height Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins