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The French Network for Animal Health ETPGAH Mirror Groups meeting Tuesday 23 November 2010 Fabienne Cournarie Director of Public Affairs, SIMV France French Network for Animal Health Why? Implementation, at the national level, of the EU guidelines and objectives defined in the ETPGAH Action Plan = « Mirror Groups » How? • Initiative of the French Ministry of Agriculture, launched in May 2007 French Network for Animal Health Who? • Ministry of Agriculture (and Fisheries) • French Agency for Sanitary Safety (ANSES) • Animal Health Industry, united in SIMV • National Veterinary Schools (ENV) • National Institute of Agronomy Research (INRA) • Agricultural Research Centre for International Development (CIRAD) • Technical Veterinarians Union (SNGTV) • Sanitary Defence Groups (farmers) (FNGDS) • Public Veterinary Diagnostic Laboratories Government Regulatoy authorities Industry Vet schools Public research organisms Vet organisations Farmers Diagnostic labs French Network for Animal Health Who? New members in 2010: • AVEF : Veterinary organization for horses welfare • AFVAC : Veterinary organization for companion animal care • INSERM : Public research organism • ITAB : Technical institute of organic farming Stakeholders covering the whole range of animal health professionals French Network for Animal Health Missions EUROPE FP-7 French Authorities Public research Private research Users: Veterinarian Farmers French Network for Animal Health Structure Steering Committee 4 working groups To provide solutions to the immediate needs Emerging diseases Europe Antimicrobial resistance Public Private cooperation French Network for Animal Health Working group 1: “orphan drugs” availability 1. Solved Issues Either by maintaining enough stocks in case of TU or by succeeding in the idea of preparing a CTD • • • • • • • Anthrax vaccine (sporadic cases): TU Q fever : CTD in progress tuberculin for ID tests Local anaesthetics for ruminants: proposal made to CVMP Oral sedation for ruminants : CTD? Dexamethasone ovine Ruminant cryptosporidosis : CTD in progress Very positive output. Having all actors (regulatory authorities, manufacturers, veterinarians and farmers) around the same table has definitely helped to define rapid and pragmatic solutions. French Network for Animal Health Working group 1: “orphan drugs” availability 2. Issues which require a European involvement • Paratuberculosis vaccine: an attenuated form is required • Histomonosis: no treatment available • Products for bee disease treatment To evaluated needs at the level of Europe To federate expertise and means French Network for Animal Health Working group 2: emerging disease 1. Concerted list of immediate (“operational”) research needs: blue tongue is a priority • Epidemiology, diagnostic tools, molecular typing, BTV status in wildlife… • Consequences on reproduction performances, on husbandry practices • Economical impacts (direct and indirect) • Vector biology and control measures • Vaccines (safety and efficacy in “minor species”) 2. Longer-term research: pathogenesis, immunology French Network for Animal Health Working group 2: emerging disease RFSA achievements on blue tongue: • Government funded research programs (total of 1,5 M€ for Short Term perspectives) : 10 projects were funded • Meeting on RFSA initiative for the review of the on going research projects on BTV (March 18th 2010 ) : among them 4 priorities were selected Success because achieved in less than 2 years French Network for Animal Health Working Group 3: Europe 1. Links with EMIDA – ERA NET, Discontools First EMIDA common calls: 77 pre-proposals were received, 45 were shortlisted, only 12 were identified for funding, 8 projects have french partners projects with french partners: “vector borne disease” : 2 “major infectious diseases affecting production”: 5 “aquaculture”: 1 French Network for Animal Health Working Group 3: Europe 2. FP7 Analyse the European project calls : analyse the reflection paper of FP7 projects calls and share the information with its partners Propose to the European commission : based on the FP7 projects calls and/or on RFSA coordinated topic priorities , propose projects to the European commission French Network for Animal Health Working Group 3: Europe List of topics proposed to the FP7 theme 2 Program committee by the french ETPGAH mirror group in January 2010 Main line 1, Animal health and non food-borne zoonoses Topics: • Ruminant pathogenic mycoplasmas: from genomics to the development of new control strategies • The assessment of the within-herd dynamics of endemic pathogens in pigs The priority of these topics has been confirmed in september 2010 French Network for Animal Health Working Group 3: Europe List of topics proposed to the FP7 theme 2 Program committee by the french ETPGAH mirror group in January 2010 (continue) Main line 2, Food borne zoonoses : Topics: • Knowledge of Trichinella nurse cell • Trichinella control Main line 3.1 Animal health and non-food borne zoonoses: Topic: • Alternative/complementary medication in organic/low-input livestock systems French Network for Animal Health Working Group 3: Europe New topics proposed to the FP7 theme 2 Program committee by the french ETPGAH mirror group in September 2010 Main line: 3.1: Animal health and non food-borne zoonoses Q Fever • “Resistant forms of C. burnetii: characterisation, role in maintenance and transmission of the disease, exploration of prophylactic strategies” • “Study of genomic plasticity and biodiversity of C. burnetii strains populations and relationships to pathoadaptation and epidemiological factors” Bee diseases • “Development and Harmonization of tests in diagnosis and bee research (HARMONY)” French Network for Animal Health Working Group 3: Europe 2. FP7 (continue) Main line 1.2: 'Omics technologies', systems biology and other basic sciences in farm animals. Gaps: Bioinformatics, systems biology, immunology Epigenetics Host-pathogen interaction, identification of protective antigens in complex pathogens Cutting edge vaccinology platform Topic: Integrating systems biology outputs to generate cutting edge vaccines and predictive protection in farm animals French Network for Animal Health Working Group 3: Europe 2. FP7 (continue) Main line 3.2: Food-borne zoonoses, antimicrobial resistance. Gaps: antimicrobial resistance Topic: Management of increased antimicrobial resistance in animal populations French Network for Animal Health Group 4: Private-public cooperation 1. Identification of subjects of interest for possible private-public cooperation: done • Antimicrobial resistance 2. To define the rules for a productive PPP cooperation • (resolution of legal aspects, technical issues…): next step 3. Links with ARIIS : • Brings together all industries involved in health (human,animals…) • Calls for projects from the French government to create institute to enhance the translational research (hospital, university, biotech/pharma companies) • Infectious disease institute was proposed including zoonoses French Network for Animal Health Antimicrobial resistance: 5 priorities Research on epidemiology and physiopathology of bacterial disease in animals Alternative to antibiotics How pathogenic are transmitted from animals to human? Contact, alimentation, environment Economics analysis Which strategies for the treatment of animals with antibiotics? A national committe for the cautious use of antibiotics will be launched in January 2011 http://www.rfsa.net/