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SANBI Glossina comparative
genomics workshop:
TDR new strategy and vector research operational
plan
Yeya T. Touré
WHO-TDR ([email protected])
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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Outline of the presentation
1. TDR new vision and strategy
2. Business Line 5: Innovative vector
control interventions: Objectives,
activities and operational plan
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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TDR new vision and strategy
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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TDR was established as a special programme 30 years ago
Mission
•
•
Track record
To develop new
and improved
tools for tropical
disease control
•
To strengthen the
research
capability of
disease endemic
countries (DECs)
•
Key strengths
Supported >10,000
projects; trained >1,500
PhD scientists
•
UN’s convening power
•
Location in WHO and links
to ministries and control
Five of 10 tropical
diseases targeted for
global / regional
elimination
•
Partner network and
brokering capabilities
•
Long-standing DEC
relationships
•
Governance structure
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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TDR Vision and Strategy
www.who.int/tdr
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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TDR Vision
To foster:
An effective global research effort
on infectious diseases of poverty
in which disease endemic
countries play a pivotal role
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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Strategic objectives
Innovation
Interventions
Access
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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Stewardship / Priority Setting
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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Empowerment through:
Training, Institutional Support and Networks
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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Cape Town 04-08 August 08
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Business Line 5: objectives,
activities and operational plan
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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BL 5 strategic objectives
Overall objective: To develop and evaluate improved and
innovative vector control methods for the prevention of
neglected diseases.
Specific objectives:
• To promote the development and testing of new methods for
improving Human African Trypanosomiasis (HAT) vector
control and support the generation and exploitation of
Glossina genome sequence data
• To advance the development and evaluation of new and
improved integrated methods for malaria and dengue vector
control
• To progress the development and evaluation of alternative
methods for the prevention of re-infestation and the control
of Chagas disease vectors
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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Building capacity in
biosafety, exploitation
of vector genome
data, training within
funded grants
Facilitating the
Glossina genome
sequencing
initiative
Development and
evaluation of
improved vector
control methods
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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Consultation meeting defined BL 5
activities and operational framework
•
Consultation on a framework for transition
from current activities and implementation of
the new vector research strategy
Geneva, 23-24 April 2007
HAT (Human African Trypanosomiasis):
- Improving bait technology, odour release systems
and trapping materials for the enhancement of
effectiveness of tsetse fly trapping
- Improving the efficacy of HAT vector control
programs through evidence-based planning and
implementation of control strategies
•
Genetic modification of malaria and dengue
vectors:
- Addressing the requirements for deployment of
genetic control methods
•
Malaria:
- Developing and evaluating tailored methods for
integrated malaria vector control
- Characterizing malaria vector resistance to
insecticides
•
Dengue:
- Improving methods for targeted and integrated
dengue vector control approaches
•
Chagas disease:
- Developing improved methods for the prevention of
re-infestation by triatomine bugs
- Developing new methods for control of Chagas
disease vectors
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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Objective 1: HAT vector control: Activities, endproducts and milestones
SANBI Glossina genomics workshop
Cape Town 04-08 August 08
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