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The Acid Fast Club Winter Meeting 2014 & AGM to be held on Friday 10th January 2014 at Birkbeck College, University of London Malet Street London WC1E 7HX Bloomsbury Local organiser: Sanjib Bhakta s.bhakta AT bbk.ac.uk; sanjib.bhakta AT ucl.ac.uk 10th January 2014 Programme 13:00 - 14:40 14:40 - 15:20 15:20 - 17:00 17:00 - 18:30 19:00 – 21:00 Session 1 Refreshments AFC AGM Session 2 Wine reception: ULU Bar (adjacent to Birkbeck main Building; http://www.ulu.co.uk/food) Dinner: Busaba Ethai, 22 Store Street, London WC1E 7DF (http://busaba.com) Nominations The following nominations for membership have been received: Teresa Cortes, NIMR, nominated by Kristine Arnvig and seconded by Douglas Young. Victoria Jenkins, Liverpool School of Tropical Medicine, nominated by Dany Beste and seconded by Johnjoe McFadden. Kerstin Williams, Imperial College, nominated by Brian Robertson and seconded by Graham Stewart. Domestic arrangements The meeting will be in Lecture Theatre Room (MALB34),Birkbeck Main Building (Torrington Square entrance). Tea and coffee will be served at 14:40 in Room (MALB33), Birkbeck Main Building (Torrington Square entrance). Wine and soft drinks will be served at 17:00 in ULU Bar (adjacent to Birkbeck main Building; http://www.ulu.co.uk/food/). Soft drinks are free but we are charging £4 per head for a glass of wine. Dinner: Busaba Ethai, 22 Store Street, London WC1E 7DF (http://busaba.com) Booking Please return the completed form below by email and hard-copy by 10th December with full payment to: Dr Sanjib Bhakta, Department of Biological Sciences, Birkbeck College, University of London, Malet Street, London WC1E 7HX. This will allow us to confirm numbers with the restaurant before Christmas. Offered papers Speakers are underlined & their affiliation indicated. Speakers are reminded that the Constitution of the Club limits the length of each talk to 15 min. 13:00 –14:40 Session 1: 13:00 – 13:20 NSAIDs to tackle drug resistance in Mycobacterium tuberculosis. Arundhati Maitra, Dimitrios Evangelopoulos, Parisa Nakhostin Mortazavi, Aleksei Kovalev, Juan David Guzman, Timothy D. McHugh and Sanjib Bhakta. Mycobacteria Research Laboratory, Institute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck, University of London, Malet Street, London WC1E 7HX. 13:20 – 13:40 Structure and Function of the Mycobacterial ACG protein family. Nicholas H. Keep, Francois Xavier-Chauviac, Doris Quay, James Torpey, Martin Bommer, Ambrose Cole. Institute for Structural and Molecular Biology, Crystallography, Dept of Biological Sciences, Birkbeck, University of London, Malet St, London WC1E 7HX. 13:40 – 14:00 Innate and antigen-specific cytotoxic cells and paradoxical HIV-1associated tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS). Katalin A Wilkinson, Naomi F Walker, Graeme Meintjes, Keira H Skolimowska, Kerryn Matthews, Rebecca Tadokera, Ronnett Seldon, Gary Maartens, Mark P Nicol, Molebogeng X Rangaka, Gurdyal S. Besra, Robert J Wilkinson. Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, and MRC National Institute for Medical Research, London, NW7 1AA. 14:00 – 14:20 High dose rifampicin therapy for a shorter treatment period. Yanmin Hu, Mitchison DA, Jindani A, Liu Y, Coates ARM. Medical Microbiology, Centre for Infection and immunity, Division of Clinical Sciences, St George’s, University of London, Cranmer Terrace, London SW17 ORE. 14:20 – 14:40 Getting to know Mycobacterium tuberculosis through metabolomics. Gérald Larrouy-Maumus, and Luiz Pedro Sório de Carvalho. Division of Mycobacterial Research, MRC National Institute for Medical Research, London, NW7 1AA. 15:20-17:00 Session 2: 15:20 – 15:40 Counting mycobacteria: how many beans make five? Han Xiao, Katarina Oravcova, Wilber Sabiiti, Eoghan Farmer, Stephen Gillespie. School of Medicine, University of St.Andrews, North Haugh, St. Andrews, Fife, KY16 9TF. 15:40 – 16:00 The pathological role of neutrophil necrosis in tuberculosis. David M Lowe, Nonzwakazi Bangani, Katalin A Wilkinson, Robert J Wilkinson, Adrian R Martineau. Department of Medicine, Imperial College London, London W2 1PG, and Clinical Infectious Diseases Research Initiative, Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory 7925, Cape Town, South Africa. 16:00 – 16:20 Role of lymph node-derived lymphatic endothelial cells in mycobacterial Infection. Maximiliano G. Gutierrez. National Institute of Medical Research, Mill Hill, London, NW7 1AA. 16:20 – 16:40 Recovery of TB genomes from metagenomes. Jacqueline Chan, Martin Sergeant, Andrew Millard, Elizabeth Wellington, Helen Donoghue and Mark Pallen. Warwick Medical School, University of Warwick, Coventry CV4 7AL. 16:40 – 17:00 Bioelectrospray-based cell encapsulation for in vitro modelling of Mycobacterium tuberculosis induced granuloma formation. Liku B Tezera, Magda K Bielecka, Victoria Workman, Patience T Brace, Brian D Robertson, Suwan N Jayasinghe, Paul T Elkington. Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton. Directions to the Venue All modes of travel are covered in detail by information at the following site: http://www.bbk.ac.uk/maps/directions-central Booking form The absolute deadline for booking is 10th December 2013 All attendees MUST fill out the booking form regardless of whether they require refreshments. Booking forms from non-members will not be accepted without the name of a sponsoring member (who does not need to attend). Please complete the booking form and send it to Dr Sanjib Bhakta, Department of Biological Sciences, Birkbeck College, University of London, Malet Street, London WC1E 7HX. Please pay for your booking by Paypal at http://www.acidfastclub.co.uk if you can, otherwise please send a cheque with the booking form payable to the Acid Fast Club. To use Paypal, select options for dinner and drinks and this will be added to your PayPal cart, where you will be able to adjust the number required. The "continue shopping" option will allow you to return to the original page to select further items if required. When finished, select "View Cart" and you will be taken to PayPal to make final adjustments and payment. Name Affiliation / Sponsor Member Y/N Coffee/tea Y/N Free Wine reception Y/N £4 Dinner Vegetarian (V) £19 Grand total enclosed Total (£) Receipt of Payment for Winter Meeting Acid Fast Club 2014 – Birkbeck College, University of London Name :………………………………………………………… Amount paid:………………………………… Cheque received by local organiser (signature): ………………………………………………. Receipts will not be sent but can be collected at the meeting