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Welcome!!! GHS Back to School Night 2012 Sarah Goldin Honors Biochemistry GHS Honors Biochemistry UNIT 1: Enhancing and Evolving to “Perfection”? Content: Natural Selection and variation DNA, genetics, and heredity Biotechnology and human impact on evolution Antibiotic resistant bacteria and genetically modified organisms Labs: Bacterial transformation with the pGLO plasmid (antibiotic resistance and GMOs) Chromatography to isolate Green Fluorescent Protein from pGLO transformed bacteria GHS Honors Biochemistry UNIT II: Causes and Treatment of Cancer Content: Environmental impact of carcinogens and evaluating relative risk Cell cycle and the genetics of cancer Radiation and mutations in causes and treatment of cancer Cellular aging, chromosomes, telomerase, and oxidizing agents Oxidiation-reduction reactions and pH Chemical reactions, equilibrium calculations, and enzymes Labs: Microscopic evaluation of cancerous versus non-cancerous cell types Design and conduct an experiment to evaluate the effect of pH on enzyme catalyzed chemical reactions GHS Honors Biochemistry UNIT III: Consciousness and Personality Content: Cell structure, emphasizing membrane structure and function Structure and function of the human nervous system and neurons Chemical and electrical signals by which neurons communicate Electrochemistry, including action potential, voltage and current Neurotransmitters, mode of action and impact on human behavior and personality Therapeutic drugs used to regulate human behavior and personality Labs: Design and conduct an experiment to determine the concentration of unknown solutions by applying the principles of osmosis Design and create an electrochemical cell to meet the energy needs of a specific therapeutic modality that relies upon an electrical current (e.g., pacemaker, AED, electric stim). GHS Honors Biochemistry UNIT IV: Drugs and Poisons Content: Classification of types of chemical reactions Solubility and concentration Impact of concentration and temperature on rate of chemical reactions Stoichiometry and conservation of mass Avogadro’s number, the mol quantity, and the Periodic Table Cellular respiration and toxins Carbon monoxide, a toxin that is the by-product of an incomplete combustion reaction Environmental impact of toxic pollutants, including effects, concentrations, and evaluation of relative risk of exposure Labs: Design and conduct an experiment to evaluate the relative risk of common combustibles for the generation of carbon monoxide Design and conduct an experiment to evaluate water quality as measured by impact on the viability of a simple aquatic organism (Daphnia)