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Viruses Biology 11 Viruses • Virus = Latin word for Poison • Viruses have both living and non-living qualities • Unlike all true organisms (even the most simple bacteria) viruses have no cellular structure – No cell membrane – No organelles (including ribosomes) Assignment Discovery - Viruses Viruses • Viruses do not require energy – or carry out other common life processes such as growth, respiration and metabolism But… • They can reproduce with a host cell Basic Structure • Very small - measured in nanometers (nm) • Two main parts: – Protein coat (a.k.a. capsid) – Core (contains DNA or RNA) Shapes of Viruses • Many different shapes: – Spherical – Rodlike – Cubical – “moon-lander” Rotavirus Tobacco Mosaic Virus H.I.V. Marburg Virus Bacteriophage – a virus that infects bacteria Lytic Cycle – see page 337 VIDEO • Understanding Viruses • Questions Dengue Fever • Life Cycle of a Virus Video Viral Replication Phage Photo Gallery Phage attaching to host More on virus shape / structure… Influenza of 1918 • Nova Science Now • Q: What does AZT do for people with HIV? • A: Inhibits the life cycle of HIV – AZT or azidothymidine is a nucleoside analog reverse transcriptase inhibitor (NRTI) – Blocks reverse transcription – HHMI Animation Q: How did chicken pox get its name? A: Not completely sure why… Theories include: 1. French word ‘ciche’ means chickpea, related to the size of the pock 2. Old English word ‘gican’, which means itch FYI: •A.k.a. Varicella zoster virus (VZV) •One of eight strains of herpes virus •Can develop into shingles later in life Test Review Jeopardy • Virus attacks prostate cancer! Getting to know VIRUSES!!! • Getting to know viruses • Profile: West Nile Virus • Viruses in the News: Using Viruses to kill bacteria? • Case Study Section I: #5 • Were the methods and procedures used by the Europeans in this historical experiment overly scientific? Why or why not? CASE STUDY