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SEPSIS
BY DR.AHMED KENSARAH
Chairman Dep. Of Surgery
DEFINITION
Sepsis can be defined as the body,s
response to an infection.
An infection is caused by
microorganisms or ;germs; (usually
bacteria) invading the body, and can
be limited to a particular body region
(tooth abscess) or can be widespread
in the bloodstream (called
;septicemia;)
People at risk
Are very young (because their immune systems
are not completely developed)
The elderly population,especially those with other
medical illnesses such as diabetes.
Have a weakened (compromised) immune system
because of treatments such as chemotherapy for
cancer,steroids for inflammatory conditions OR
because of an illness, such as AIDS.
Have wounds or injuries
Have certain addictive habits such as alcohol or
drugs.
Are receiving certain treatments or examinations
e.g.,IV catheters,urinary catheters,drains
Symptoms And Signs
Increase heart rate>90 beats per
minute.
Body temperature>38c.
Hyper
ventilation>20,PaCO2<32mm Hg.
White blood cell count>12000 or
<4000 cells/mm3
Treatment
Antibiotics.
Surgical drainage.
Fluid replacement.
Appropriate support for organ
dysfunction.
The forms of sepsis
Uncomplicated sepsis.
Severe sepsis.
Septic chock.
Complications
Spread of the infection.
Bactraemia.
Septic joint.
DIC.
Acute tubular necrosis.
Arrythmia.
Ileus or ischemic colitis.
Multiple organ dysfunction syndrome.
Meningitis.
Osteomyelitis.
Endocarditis.
Pyaemia.
Septic chock.
Antibiotic
Definition ; An antibiotic is a drug that
kills or slows the growth of bacteria.
Classification
Bactericidals; kill bacteria directly.
Bacteriostatics ; prevent them
dividing.
Side effects
Fever.
Nausea.
Allergic reactions.
Diarrhoea.
Interaction with other drugs.
Antibiotic resistance.