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Transcript
The Oral Systemic Link and the Future of Patient Care Jamie Toop, DDS @ASDAnet #ASDAnet About Me… @ASDAnet #ASDAnet “I would give all my possessions for a moment in time” WHAT ARE THE 7 LEADING CAUSES OF DEATH IN AMERICA? (according to the CDC) @ASDAnet #ASDAnet Leading Causes of Death 1. Heart Disease 2. Cancer 3. Chronic Lower Respiratory Diseases 4. Stroke 5. Accident 6. Alzheimer's 7. Diabetes @ASDAnet #ASDAnet WHAT DO THESE CONDITIONS HAVE IN COMMON? Six of the top seven leading causes of death in America have been associated with conditions in the mouth. @ASDAnet #ASDAnet “The View” on Oral Systemic Link • https://www.youtube. com/watch?v=XLDL8Nh NxWA @ASDAnet #ASDAnet 1. Heart Disease Associations Research Has Shown: • • • • Brushing < 2x/day = ↑ risk Gum disease → 60% ↑ risk of heart disease Gum disease → heart disease death 2x as likely Gum disease and cholesterol levels predictors @ASDAnet #ASDAnet Gum Disease— Heart Disease Mechanism Infection/inflammatory components in gums • Enter blood stream • Can be carried to heart/coronary arteries • Limits blood flow @ASDAnet @ASDAnet #ASDAnet #ASDAnet 2. Cancer Associations Research Has Shown: • Gum disease → 62% ↑ risk (pancreatic/kidney) • Pancreatic cancer • 4th leading cause of cancer-related death • Detection difficult • 5 year survival rate 21.5% if detected early • Pancreatic cancer ↑ bacteria levels in saliva @ASDAnet #ASDAnet Other Cancer Associations Research Has Shown: Men with gum disease • ↑ associations of gum disease and cancer • 30% ↑ risk to develop cancers of the blood • ↑ risk of prostate cancer • ↑ level of prostate-specific antigen secretion • Saliva test in development may detect sooner @ASDAnet #ASDAnet 3. Chronic Lower Respiratory Associations Research Has Shown: • • • • Oral cavity may play central role Relationship between oral hygiene and COPD Gum disease bacteria can be aspirated in lungs Respiratory pathogens can colonize in teeth @ASDAnet #ASDAnet 4. Stroke Association Research Has Shown: • • • • Gum disease →3x ↑ likelihood to die from stroke Severe gum disease 4.5x ↑ risk of stroke Correlation ↑ in men and in those under 60 Gum disease bacteria enters blood stream • Plaques form, can dislodge and enter brain @ASDAnet #ASDAnet 5. Alzheimer’s (AD) Association Research Has Shown: • AD irreversible - prevention key • Declines in oral hygiene shown in AD patients • Loss of teeth from gum disease ↑ AD risk • Gum disease bacteria enters blood stream • Can cause neuroinflammation • Limits neurotransmitter activity @ASDAnet #ASDAnet 6. Diabetes Association Research Has Shown: • • • • Diabetics with gum disease 3.2x ↑ risk of death Diabetic control ↑ with improved oral hygiene Infection/inflammatory components move in blood More research to establish causal relationship @ASDAnet #ASDAnet Causal vs. Correlative Relationship of Oral/Systemic Link Can we establish a causal relationship? @ASDAnet #ASDAnet GINGIVITIS—MATH AND VERBAL RECALL ASSOCIATION According to webmd.com, using antimicrobial mouthwash or toothpaste can make you less bad at math. @ASDAnet #ASDAnet LET’S DO SOME “CALCULUS” @ASDAnet #ASDAnet • • • • • Pick a number between 1 and 10 (though this will work with any number) Double it Add 10 Divide by 2 Subtract your original number WHAT NUMBER DO YOU HAVE? @ASDAnet #ASDAnet IF YOU DON’T HAVE… @ASDAnet #ASDAnet WHAT TO WATCH OUT FOR… • • • Credibility of the publication Parameters of the study Repeatability • Be careful to throw out what you know is true @ASDAnet #ASDAnet Erectile Dysfunction (ED) Research Has Shown: • Men in 30s with gum disease 3x ↑ risk of ED • Infection/inflammatory components in gums • Travels in blood stream, forms plaques • Limits blood flow • Can cause impotence - blood vessel damage @ASDAnet #ASDAnet Pre-term Birth Research Has Shown: • Mothers with gum disease • 85% chance pre-term/low birth weight • Gingivitis 3x ↑ risk • Moderate gum disease 8x ↑risk • Oral bacteria in pre-term placentas @ASDAnet #ASDAnet Oral Systemic Link and the Future of Patient Care • • • • More research to establish causal relationships Draw conclusions from existing data Detection/prevention of disease far from oral cavity Nothing to lose in treating gum disease • Eliminating can ↑ life by 6.5 years! @ASDAnet #ASDAnet So, tell your patients to: @ASDAnet #ASDAnet Then, tell them to: @ASDAnet #ASDAnet And finally, tell them: @ASDAnet #ASDAnet