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STRING examples • Go to the STRING web site http://string.embl.de • Examples for “Protein mode” MURC_TREPA ANP1_YEAST • Lookup examples Judge the correctness of the predictions Use the evidence viewers to understand the basis for the predictions • Feel free to also lookup proteins that you are interested in or to use the ”random” link Lars Juhl Jensen, EMBL Heidelberg • Examples for “COG mode” COG0055 COG1117 • Examples for comparing the two different modes trpB P91427 Examples for ab initio prediction methods • Go to the following services GlobPlot http://globplot.embl.de DisEMBL http://dis.embl.de ELM http://elm.eu.org ProtFun http://www.cbs.dtu.dk/services/ ProtFun/ • Submit the following examples and interpret the results PRIO_HUMAN P53_HUMAN Lars Juhl Jensen, EMBL Heidelberg • Go to the following services TargetP http://www.cbs.dtu.dk/services/ TargetP/ PSORT http://psort.nibb.ac.jp/ ExPASy ProtParam http://www.expasy.org/tools/prot param.html • Try to predict the subcellular localization of these calpains CANA_HUMAN CAN1_HUMAN (CAN2_HUMAN)