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Springboard Toolbox # Genetic Disorders Normal Chromosomes Trisomy 21 or Downs Syndrome- affected individuals live short lives and have severe developmental problems Having the wrong number of sex chromosomes often leads to the inability to reproduce properly. Sex-linked disorders Hemophelia- x-linked disorder where blood can not clot properly, causing the person to bleed much more than normal. Note the recessive x on the mother. Because males get one x they are Much more likely to have this trait. Sex linked gene- an allele that is inherited with a sex chromosome. Recessive Disorders < Cystic Fibrosis, a condition where fluid clogs the lungs intefering with breathing Sickle Cell> Blood cells take a sickle shape, clogging the bloodstream leaving the person weak A pedigree is a chart used by geneticists to track the inheritance of a trait over several generations Pedigrees allow doctors to determine if a child would be at risk for developing a condition, or if future children could pick up that condition. I II III IV 1. 2. 3. 4. Which members of this family have the trait? Which generation did the trait skip? Is this trait dominant or recessive? Would generation 4’s children be at risk inheriting the trait?