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Cell Reproduction Biology Ch. 10 & 11 The Cell Cycle 1. All living things are composed of one or more cells 2. Cells are an organisms basic unit of structure and function 3. Cells come only from existing cells. I. Why do cells divide? A. Cells have a lifespan red blood cells less than 120 days lining of sm intestine 1-2 days white blood cells 10 hrs to decades B. DNA Overload C. Lower efficiency due to low surface area to volume ratio II. Chromosomes A. DNA in a coiled, rod-shaped form that occurs during cell division B. Chromosome Structure 1. chromatin a. the DNA and proteins in the nucleus of a nondividing cell b. thin, uncoiled strands (easier to read) c. as a cell begins to divide, they form chromosomes 2. Each chromosome consists of 2 identical parts called chromatids 3. The point at which the chromatids are attached is the centromere a. during cell division the centromere releases the chromatids allowing one sister chromatid to go to each of the two daughter cells http://www.uic.edu/classes/bios/bios100/labs/realchromo.jpeg C. Chromosome Numbers of Various Species http://en.wikipedia.org/wiki/Chromosome C. Chromosome Numbers of Various Species http://en.wikipedia.org/wiki/Chromosome Human Chromosomes and DNA http://en.wikipedia.org/wiki/Chromosome Humans – 46 chromosomes 1. Prokaryotes usually have only one chromosome 2. Sex Chromosomes a. chromosomes that determine the sex of an organism b. humans XX female XY male 3. Autosomes a. any chromosome that is not a sex chromosome 4. Homologous Chromosomes/Homologues a. one of two members of a pair of morphologically similar chromosomes b. same size and shape c. structurally different from other chromosomes in the cell 5. Karyotype a. a picture of an individual’s chromosomes http://members.aol.com/chrom info/images/bigktype.gif 6. Diploid a. cell that contains both homologous pairs b. 2n c. ie – humans 46 7. Haploid a. a cell that contains only half of the homologues b. 1 n c. ie – humans reproductive cells – egg and sperm - 23 8. Polyploidy a. cells with more than two copies of each chromosome Watermelon http://edis.ifas.ufl.edu/EDISImagePage?imageID=353335001&dlNumbe r=CV006&tag=IMAGE%20CV:CV006P2&credits=; grapes http://www.nysaes.cornell.edu/hort/faculty/reisch/Varietyphotos/canadice.JPG 8. Polyploidy b. triploid – banana, apple, watermelon, tulips c. tetraploid – wheat, maize, cotton, potato, peanut d. hexaploid – chrysanthemum, wheat, oats e. octaploid – strawberry dahlia, pansies, sugarcane Sugarcane - http://www.food-info.net/images/sugarcane2.jpg; tulips http://www.theflowerexpert.com/media/images/aboutflowers/exoticflowers/tulips/muti-hued-tulips.jpg Invasive Species - Asian carp http://www.epa.gov/glnpo/invasive/asiancarp/ http://www.fws.gov/home/feature/2007/jumping-carp.jpg II. Cell Division A. Cell Division in Prokaryotes 1. Binary Fission a. the division of a prokaryotic cell into two identical cells Binary Fission http://en.wikipedia.org/wiki/Binary_fission B. Cell Division in Eukaryotes 1. Mitosis a. cell division in new cells with genetic material that is identical to that of the original cell b. occurs in the reproduction of unicellular organisms c. occurs in the addition of cells to tissue or organs in multicellular organisms d. DNA and information stays the same f. The Cell Cycle 1) the sequence of events from mitosis to mitosis http://www.pbs.org/wgbh/nova/baby/divi_t ext.html How Cells Divide website 1. Interphase a. G1 phase b. S phase c. G2 phase 2. Mitosis a. Prophase b. Metaphase c. Anaphase d. Telophase 3. Cytokinesis http://www.uoguelph.ca/zoology/devobio/210 labs/mitosis1.html http://www.uhh.hawaii.edu/~ronald/392/Mitosis.JPG IV. Regulating the Cell Cycle A. Controls on Cell Division B. Cell Cycle Regulators 1. Cyclins a. a family of proteins that regulate the timing of the cell cycle in eukaryotic cells 2. Internal Regulators a. allow cell cycle to continue only when correct order of events is followed (ie – DNA is replicated before chromosomes are pulled apart) 3. External Regulators a. growth regulators cause cells to multiply rapidly when neighboring cells die C. Uncontrolled Cell Growth 1. Cancer cells do not respond to the signals that regulate cell growth 2. form tumors V. Meiosis A. the process of nuclear division that reduces the number of chromosomes by half B. 1n C. egg and sperm cells D. 2 nuclear divisions http://encarta.msn.com/encnet/refpages/searchdetail.aspx?grp=art&pg=1&q=sperml; http://news.bbc.co.uk/nol/shared/spl/hi/pop_ups/03/health_ivf_step_by_step/img/1.jpg E. Phases of Meiosis 1. Interphase 2. Meiosis I a. Prophase I b. Metaphase I c. Anaphase I d. Telophase I 3. Interkinesis 4. Meiosis II a. Prophase II b. Metaphase II c. Anaphase II d. Telophase II 5. Cytokinesis F. Crossing Over 1. during Meiosis I the 4 homologous chromosomes form a tetrad 2. the tetrad exchanges parts of their chromatids Crossing Over G. Formation of Egg and Sperm 1. gametes a. sexual reproductive cells b. egg and sperm http://www.moe.gov.sg/edsoftware/ir/files/bio-meiosis/images/introduction/image3a.jpg 2. ootid a. egg cell b. gets all the cytoplasm 3. polar bodies a. receive little or no cytoplasm and eventually disintegrate http://en.wikipedia.org/wiki/Gametogenesis H. Asexual Reproduction 1. the production of offspring that does not involve the union of gametes 2. 1 parent 3. no union of gametes 4. unicellular organisms a. binary fission b. mitotic division http://en.wikipedia.org/wiki/Binary_fission 5. Multicellular organisms a. cloning b. budding 6. Genetically identical to parents Hydra budding - http://biology.about.com/library/weekly/aa090700a.htm; strawberry http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/AsexualReproduction.html I. Sexual Reproduction 1. the production of offspring from the exchange of genetic material 2. meiosis and union of gametes 3. offspring are genetically different from their parents http://images.google.com/imgres?imgurl=http://plantandsoil.unl.edu/croptechnology2005/UserFiles/Image/siteImages/B73Mo17,hybridEarsLG.gif&imgrefurl=http:/ /plantandsoil.unl.edu/croptechnology2005/pagesincludes/printModule.jsp%3FinformationModuleId%3D1075412493&h=467&w=600&sz=146&hl=en&start=66&um =1&tbnid=xNSE8IzI1BUZM:&tbnh=105&tbnw=135&prev=/images%3Fq%3Dhybrid%2Bcorn%2Bpicture%26start%3D60%26ndsp%3D20%26um%3D1%26hl%3Den%26sa%3DN J. Linkage and Gene Maps 1. Gene Linkage a. chromosomes are assorted independently b. individual genes can be inherited together 2. Gene Map a. the further two genes were apart on a chromosome the less likely they would be inherited together Gene Map