Download 2_10_14-PBS Day 20

Turn in HW (Do Now
and EC) to the front
Do Now—2.10.14

Arthur really wants a male child with free
earlobes. Kim really wants a female child with
attached earlobes. Free earlobes (F) are
dominant to attached earlobes (f). Arthur has
attached earlobes and Kim is homozygous
dominant.

Is Arthur or Kim more likely to have the desired
child?
Turn in HW (Do Now
and EC) to the front
Do Now—2.10.14
Is Arthur or Kim more likely to have the desired
child?
Arthur is the only one who can get what he wants.
50% chance of him getting the child he wants. 0%
chance of the child Kim wants because they can’t
have a female child with attached earlobes.
Pedigree
F
F
X 3: Y 50% chance female
50% chance male
Ff
f Ff
X XX XY
100% free earlobes
Ff
X XX XY 0% attached earlobes f Ff

Unit 3: Sickle Cell Disease
Test Review and Community
Builder
2.10.14
Objectives
 SWBAT
 SWBAT
review for their unit test.
develop a strong sense of
community in the classroom.
Test Review
Homozygous dominant
Brown hair
Heterozygous
Blonde hair
Brown hair
ww
WW or Ww
Ss
50%
50%
ss
S
s Ss
s
ss
s Ss
50
ss
Test Review
W
w
W WW Ww
w Ww
25%
25%
ww
No, ff is attached earlobes. This couple cannot have a
child with attached earlobes because there is a 100%
probability of free earlobes (Ff)
F
F
f
Ff
Ff
f
Ff
Ff
Test Review
ff
Ff
Ff
F?
Ff
Ff
Ff
Ff
ff
Pedigree
3:
ff
F?
Ff
F? F?
4
7
5
ff
F?
F
f
F
FF
Ff
f
Ff
ff
25% chance of child with
Probability the child will have sickle cell diseasecystic
is ______________________.
fibrosis
children also had the trait. Generations are drawn underneath the
families. Pedigrees are
oftengenerations,
used to determine
mode
of
parental
with the the
oldest
generation
at the top of the
pedigree
and the
oldest
individuals
within a generation drawn furthest to the left.
inheritance (dominant,
recessive,
etc.)
of genetic
diseases.
If the
purpose males
of a pedigree
is to represent
analyze the pattern of inheritance of a particular trait, it is
In a pedigree, squares
represent
and circles
customary
to
shade
in
the
symbol
of
all
individuals
females. Horizontal lines connecting a male and female representthat possess this trait. If someone does not have the
trait
leave the downward
person blank.
If the
person represent
is a carrier they have the allele but do not have the trait so
mating. Vertical lines
extending
from
a couple
they
are
only
half
shaded—when
a
person
is
heterozygous for a recessive disease. Carriers are not
their children. In the pedigree above, the grandparents had two
shownThe
in ason
pedigree.
Iftrait.
you cannot
determine
children, a son and aalways
daughter.
had the
One of
his four someone’s genotype you but a ‘?’.
children also had the trait. Generations are drawn underneath the
aa"
AA"
parental generations, with the oldest generation
at the Dominant
top of the(A)
Autosomal
pedigree and the oldest individuals within a generation
furthestdominant
to the left.
-Person can drawn
be homozygous
or heterozygous to show trait
If the purpose of a pedigree is to analyze
the pattern
of parents
inheritance
a particular
trait, it is
-At least
one of the
mustof
have
trait
-If you that
cannot
determine
allele youdoes
but anot
‘?’. have the
customary to shade in the
of all individuals
possess
this someone’s
trait. If someone
Aa"symbolaa"
trait leave the person blank. If the person is a carrier they have the allele but do not have the trait so
they are only half shaded—when a person is heterozygous for a recessive disease. CarriersAa"
are not Aa"
Autosomal Recessive (a)
always shown in a pedigree. If you cannot determine someone’s genotype you but a ‘?’.
Test Review
Dd
A?"
Dd
dd
Dd
dd
Aa"
aa"
Aa"
dd
A?"
Pedigree Practice: Autosomal
Dominant (Shaded person can be homozygous dominant or heterozygous)
Pedigree Practice: Autosomal Recessive (Shaded person must be homozygous recessive)
Write the genotypes
of each
in of
theeach
pedigree
below
assuming
a dominant
Write
the person
genotype
individual
next
to the symbol.
If antrait.
individual is a carrier, then indicate it.
Hh
hh
Hh
HH
dd
Hh
Hh
hh
HH
Autosomal Dominant (A)
-Person can be homozygous dominant or
-At least one of the parents must have t
-If you cannot determine someone’s allel
dd
Autosomal Dominant (A)
-Person can be homozygous dominant or h
-At least one of the parents must have tr
-If you cannot determine someone’s allele
Autosomal Recessive (a)
-Person must be homozygous recessive to show trait
-Parents do not have to have the trait for a child to have it
-People can be carriers (have allele but not trait = heterozygous)
-If you cannot determine someone’s allele you but a ‘?’.
AA"
aa"
Write the genotypes of each person in the pedigree below assuming a dominant trait.
AA"
dd
dd
aa"
aa"
dd
aa"
Dd
Dd
Aa"
Pedigree Analysis
A pedigree is a diagram of family relationships that uses sym
Autosomal
Recessive
(a)
represent
relationships.
Theseto
diagrams
make it easier to
-Person
mustgenetic
be homozygous
recessive
show trait
visualize relationships within families, particularly large
extended
-Parents
do
not
have
to
have
the
trait
for
a
child
to
have
it
families.
are(have
oftenallele
used but
to determine
mode of
-People
can Pedigrees
be carriers
not trait the
= heterozygous)
inheritance (dominant, recessive, etc.) of genetic diseases.
-If you cannot determine someone’s allele you but a ‘?’.
In a pedigree, squares represent males and circles represen
females. Horizontal lines connecting a male and female represen
Pedigree Practice: Autosomal Dominant (Shaded person can be hom
mating. Vertical lines extending downward from a couple repres
Write the genotypes of each person in the pedigree below assumin
their children. In the pedigree above, the grandparents had two
children, a son and a daughter. The son had the trait. One of his fo
children also had the trait. Generations are drawn underneath the
parental generations, with the oldest generation at the top of the
pedigree and the oldest individuals within a generation drawn furth
If the purpose of a pedigree is to analyze the pattern of inh
customary to shade in the symbol of all individuals that possess thi
trait leave the person blank. If the person is a carrier they have th
they are only half shaded—when a person is heterozygous for a rec
aa"
Aa"
always Practice:
shown in aAutosomal
pedigree. If
you cannot
determine
someone’s
genh
Pedigree
Recessive
(Shaded
person
must be
Write the genotype of each individual next to the symbol. If an in
dd
-Person can be homozygous dominant or heterozygous to show trait
-At least one of the parents must have trait
Pedigree Practice: Autosomal Dominant (Shaded person can be homozygous dominant or heterozygous)
-If you cannot determine someone’s allele you but a ‘?’.
dd
aa"
Autosomal Recessive (a)
-Person must be homozygous recessive to show trait
-Parents do not have to have the trait for a child to have it
-People can be carriers (have allele but not trait = heterozygous)
-If you cannot determine someone’s allele you but a ‘?’.
Aa"
AA"
Pedigree Practice: Autosomal Dominant (Shaded person can be hom
Write the genotypes of each person in the pedigree below assumin
Pedigree Practice: Autosomal Recessive (Shaded person must be ho
Write the genotype of each individual next to the symbol. If an ind
aa"
-Person must be homozygous recessive to show trait
-Parents do not have to have the trait for a child to have it
-PeopleAutosomal
can be carriers
(have allele
Dominant
(A) but not trait = heterozygous)
-If you cannot determine someone’s allele you but a ‘?’.
Test Review
XHXh
XHY
XHXh
XHY
XHX?
XHX? XHX? XHX? XHY XHY XHY XhY
XHXh
XHY
XhY
h
h
H
XY XY X Y
XHY XHXH XHXH
XHY
XhY
Test Review
Meiosis makes gametes, which are the sex cells that make offspring
when they are united. Meiosis makes four non identical haploid cells
(gametes). Alleles are randomly passed into the gametes during
meiosis.
Mitosis is two identical diploid somatic (body) cells formed.
Homework
 Study
for your test tomorrow!
Community Builder
 Two
truths and a lie
 Think of two things that are true about
you but sound like a lie. Then you are
going to share with the class the three
statements (two truths and a lie), we
are going to try and determine what
the lie is!!!!
Community Builder
 Write
down one nice thing about each
person in the class—including
yourself.
down one constructive thing –
something they could change or
improve upon.
 Write