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INDUCED FLAVOUR HYDROLYZED EQUINE HEMOGLOBIN PRODUCT PROFILE SYNTEX S.A. Luis De Sarro 501 - (B1838DQK) – Luis Guillón – Buenos Aires – Argentina – Tel./Fax: (54 11) 4367-6100 [email protected] – www.syntexar.com Brief Introduction Enzymes use in food industry is a well known and constantly expanding phenomenon. Enzymes represent a natural choice for food manufacturers because they are proteins and they accomplish their catalytic task, but they have already disappeared by the time they are consumed. Proteolytic enzymes are also used in the manufacturing of stock cubes, soups, meat flavourings and balanced food obtained from cuts, leather and scrap byproducts of meat industry, in order to obtain useful meat proteolyzed in human and animal food industry (1) (2). So, nothing that does not belong to the start animal tissue is added, having a meat flavoured hydrolyzed that is not bitter or disagreeable as a result. This is accomplished at the mercy of specific technologies with proteolytic enzymes commercialized by important international corporations specialized in the technology of industrial enzymes development. In the field of human and animal food industrial elaboration, there is a highly interesting process: the enzymatic hemoglobin treatment, or best, the blood globular fraction of animals destined to human consumption. Enzymatic hydrolysis of blood or erythrocytic package has permitted the obtaining of valuable products, as well as the industrial exploitation of this extremely contaminant residue. For example, in the countryside suckling pigs obtain iron naturally while if raised in corrals, conversely, this does not happen. Iron injectable supplying is a compulsory supplement to avoid animal death. The substitution of injectables for oral administration treatments is desirable but there are no yet feasible alternatives (3). Enzymatic hemoglobin treatment practiced with industrial enzymes allows the separation of a globinic and almost colourless hydrolyzed, of a strong meat flavour and apt for the constitution of animal fodder and food. Liberated iron, on the other hand, is obtained as a dark and pasty suspension that is separable through centrifugation. Obtained materials are not of blood aspect or flavour on the contrary, they are of an attractive and definite meat flavour of an adjustable composition with different organic iron tenors (Hemo). SYNTEX S.A. Luis De Sarro 501 - (B1838DQK) – Luis Guillón – Buenos Aires – Argentina – Tel./Fax: (54 11) 4367-6100 [email protected] – www.syntexar.com Use Even though these materials may be apt for human food fortification and additivation, Syntex has neither developed application assays in this respect nor including them in balanced food for animals. However, use of these products with these ends is documented enough in bibliography (4) (5) (6) (7) (8) (9). From these considerations come the following guidelines that can certainly be expanded by the food science and technology expert, namely: • • • • Balanced food inclusion where a strong meat flavour is desirable (dogs, cats, etc.) Inasmuch as they are extensively digested hydrolyzed and they therefore contain a big quantity of free amino acids, they should be apt for any farm animal nutrition, including poultry. As it was previously detailed, the presence of amino acids in their natural “levo” form ensures good bioavailability in animal ´s organism, giving adequate biostimulation as a result. Animal species suggested to make use are ovines, swine, poultry, rabbits, dogs, cats and equines. In addition, in developing regions fermented and/or cooked blood flour is used to feed sucking pigs (10). As it was previously explained, the product that is presented naturally differs conceptual and chemically from blood flour in any of its forms. Production Syntex S.A. has developed and produced hemoglobinic hydrolyzed to bench-top scale (multigram-kilo lab) Patent Status Being methods, products and use perfectly documented, they constitute prior art and this development is not therefore susceptible of patenting. Note Ideas and data previously mentioned must be understood just as guidelines in applications development and not as a recommendation of use against any patent. SYNTEX S.A. Luis De Sarro 501 - (B1838DQK) – Luis Guillón – Buenos Aires – Argentina – Tel./Fax: (54 11) 4367-6100 [email protected] – www.syntexar.com Bibliographic Reference 1. Biotimes, N°2, June 1996, 4-5 (Novo Nordisk A/S) 2. Biotimes, N°3, September 1997, 8-9 (Novo Nordisk A/S) 3. Biotimes, N°3, September 1993, 14-15 (Novo Nordisk A/S) 4. Biotimes, N°4, December 1998, 8-9 (Novo Nordisk A/S) 5. Biotimes, N°2, June 2003, pag. 3 (Novo Nordisk A/S) 6. Biotimes, N°1, March 1997, 14-15 (Novo Nordisk A/S) 7. Biotimes, N°3, September 1993, 14-15 (Novo Nordisk A/S) 8. Novo Nordisk, Application Sheet, 2001-06803-02 9. Product Sheet, B717e-GB 1000, May 1996, HCH-Novo Nordisk A/S 10. King’ori, Am et al, Tropical Animal Health Production, 30 [3], 191-6 (1998) SYNTEX S.A. Luis De Sarro 501 - (B1838DQK) – Luis Guillón – Buenos Aires – Argentina – Tel./Fax: (54 11) 4367-6100 [email protected] – www.syntexar.com