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BIOMOLECULES copyright cmassengale 1 • Video http://youtube.com/watch?v=AfXxZwNLvPA copyright cmassengale 2 Elements & Compounds electron • All living things are made from chemical compounds. • Those compounds are built using elements and molecules. 2 or more elements combined together ( NaCl, H2O, C6H1206 ) – The basic unit of an element is an atom. • Consists of electrons, protons and neutrons – Each atom is then combined to form molecules. – Different combinations form different molecules. • Take pizza for example: Using different ingredients we build different types of pizzas. Your basic cheese, then pepperoni, pepperoni with sausage…and so on. neutron proton EXIT CARD • What elements and how many of each are found in the compound • H2SO4 • What is the difference between an element and a compound? copyright cmassengale 4 An atom refresher • An atom has three parts: • Proton = positive • Neutron = no charge • Electron = negative • The proton & neutron are found in the center of the atom, a place called the nucleus. • The electrons orbit the nucleus. Created by G.Baker www.thesciencequeen.net Picture from http://education.jlab.org/qa/atom_model_ 03.gif More about Elements.. • Elements are the building blocks of all matter. • The periodic table is a list of all of the elements that can build matter. It’s a little like the alphabet of chemistry. • The periodic table tells us several things… Created by G.Baker www.thesciencequeen.net Periodic Table Atomic number Tells protons and electrons Symbol of element Name of element Atomic mass is The number of protons and Neutrons 8 O Oxygen 16 Finding Neutrons Subtract Mass from Atomic Number Created by G.Baker www.thesciencequeen.net Compounds and Molecules • Elements combine to form molecules and compounds that are found in living things • Electrons are arranged around the nucleus in shells. • Valence Electrons (in outermost shell) in atoms are what allows elements to bond to each other. • Valence electrons can be transferred or shared • Valence Electrons can be determined by position on the periodic table copyright cmassengale 8 Periods •Each row is called a “period” •The elements in each period have the same number of shells www.chem4kids Groups-valence electrons Group 8 = 8 electrons Except for Group 1 = 1 electron He, it has 2 electrons Group 2 = 2 electrons •Each column is called a “group” •Each element in a group has the same number of electrons in their outer orbital, also known as www.chem4kids “shells”. Determine the number of shells and the number of valence electrons for: 2nd Period = 2 shells 4th Group = 4 valence electrons www.chem4kids Determine the number of shells and the number of valence electrons for: 3rd Period = 3 shells 1st Group = 1 valence electron www.chem4kids Write your answers on your handout. Name the element. Number of shells ? Valence electrons ? Write your answers on your handout. Name the element. Number of shells ? Valence electrons ? Neon 2nd Period = 2 shells 8th Group = 8 valence electrons PERIODIC TABLE REVIEW • • • • • • • Symbol of element Name of element Atomic number Atomic mass Number of protons Number of neutrons Number of electrons 2. What elements and how many atoms of each are in C6H14N2O2 copyright cmassengale 15 % Major Elements in the Body O 65.0 % C 18.0 H 10.0 N 3.0 Ca 1.4 P 1.0 Mg 0.50 K S Na Cl Fe Zn 0.34 0.26 0.14 0.14 0.004 0.003 LecturePLUS Timberlake 16 REVIEW copyright cmassengale 17 Ionic vs. covalent Bonding Elements will either give away, take, Or share their valence electrons in order to form Compounds and molecules Ionic Bond – give or take Electrons Metal + Nonmetal Covalent Bond – share Electrons Nonmetal + Nonmetal copyright cmassengale 18 IONIC BONDS Na = Metal (like to give Electrons) Cl = Nonmetal ( like to take electrons) Covalent Bonds • Two nonmetals • Like to share EXAMPLE copyright cmassengale 21 copyright cmassengale 22 CHEMICAL REACTIONS • When bonds form or bonds break a chemical reaction occurs • When sodium (Na) bonds to chlorine (Cl) salt is produced 2Na + Cl2 → 2NaCl • Breaking bonds can release energy in the form of ATP C6H12O6 → 6C + 6H20 copyright cmassengale 23 REVIEW QUIZ • Draw a bohr model for the element –Ca ( Calcium) • What are the two ways in which elements can bond to Form molecules and compounds copyright cmassengale 24 Organic Compounds • Compounds that contain CARBON are called organic compounds • Chemical Formulas tell us what elements and how many of them are in the molecule. • C6H12O6 copyright cmassengale 25 Carbon (C) • Basic unit of most biomolecules • Carbon can form covalent bonds with as many as 4 other atoms (elements). Forming biomolecules • Usually with C, H, O or N. • Example: CH4(methane) copyright cmassengale 26 Biomolecules • Large organic molecules. • Also called POLYMERS. • Made up of smaller “building blocks” called MONOMERS. • Examples: 1. Carbohydrates - Sugars 2. Lipids- fatty acid, 3 glycerols 3. Proteins – amino acids 4. Nucleiccopyright acids (DNA and RNA) cmassengale 27 copyright cmassengale 28 Question: How Are biomolecules Formed? copyright cmassengale 29 Answer: Dehydration Synthesis • Also called “condensation reaction” • Forms polymers by combining monomers by “removing water”. HO H HO H H2O HO H copyright cmassengale 30 Dehydration Synthesis of a Disaccharide copyright cmassengale copyright cmassengale 32 copyright cmassengale 33 Question: How are biomolecules separated or digested? copyright cmassengale 34 Answer: Hydrolysis • Separates monomers by “adding water” HO H H2O HO H copyright cmassengale HO H 35 http://www.youtube.com/watch?v=MnnfN5BI X7E&list=PLE7B2BB1EB05699BC copyright cmassengale 36 Carbohydrates copyright cmassengale 37 Carbohydrates • Small sugar molecules to large sugar molecules. • Examples: A. monosaccharide B. disaccharide C. polysaccharide copyright cmassengale 38 FUNCTION • Short term energy • Structural components – Chitin – shells of animals – Cellulose – stalks of plants • Cell Recognition – Sugars on cells can detect invaders copyright cmassengale 39 Carbohydrates Monosaccharide: one sugar unit Examples: glucose- simple sugar found in juices (C6H12O6) Fructose – corn syrup/cereals Galactose – sugar found in dairy products glucose copyright cmassengale 40 Carbohydrates Disaccharide: two sugar unit Examples: – Sucrose (glucose+fructose) – Lactose (glucose+galactose) – Maltose (glucose+glucose) glucose glucose copyright cmassengale 41 Carbohydrates Polysaccharide: many sugar units Examples: starch (bread, potatoes) glycogen (beef muscle) cellulose (lettuce, corn) glucose glucose glucose glucose cellulose glucose glucose glucose copyright cmassengale glucose 42 Carbohydrate Shapes Can be rings or a straight chain But will always have C, H, O Review 1. How many sugars are in a monosaccharide? 2. What is one function of a carbohydrate? 3. How are biomolecules broken apart? Condensation reaction or hydrolysis 4. What does the atomic number on the periodic table tell you ? copyright cmassengale 44 Lipids copyright cmassengale 45 Lipids • General term for compounds which are not soluble in water. • Remember: “stores the most energy” • Examples: 1. Fats 2. Phospholipids 3. Oils 4. Waxes 5. Steroid hormones 6. Triglycerides copyright cmassengale 46 Lipids Six functions of lipids: 1. Long term energy storage 2. Protection against heat loss (insulation) 3. Protection against physical shock 4. Protection against water loss 5. Chemical messengers (hormones) 6. Major component of membranes (phospholipids) copyright cmassengale 47 Lipids Triglycerides: composed of 1 glycerol and 3 fatty acids. H O H-C----O C-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH3 O H-C----O C-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH3 O fatty acids H-C----O C-CH -CH -CH -CH 2 2 2 H glycerol copyright cmassengale 48 Fatty Acids There are two kinds of fatty acids you may see these on food labels: 1. Saturated fatty acids: no double bonds (bad) O saturated C-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH3 2. Unsaturated fatty acids: double bonds (good) O unsaturated C-CH2-CH2-CH2-CH copyright cmassengale 49 Shapes of fatty acids Saturated fats = solid fats butter, lard, animal fat Unsaturated fats = liquid fats STEROIDS • Composed of four fused carbon rings • Familiar steroid in humans is cholesterol – Help with chemical processes in the body (metaboloism), growth, and sex hormones (estrogen and testosterone) Proteins copyright cmassengale 52 Proteins (Polypeptides) • Amino acids (20 different kinds of aa) bonded together by peptide bonds (polypeptides). • Six functions of proteins: 1. Storage: albumin (egg white) 2. Transport: hemoglobin 3. Regulatory: hormones 4. Movement: muscles 5. Structural: membranes, hair, nails 6. Enzymes: cellular reactions copyright cmassengale 53 Proteins (Polypeptides) Four levels of protein structure: A.Primary Structure B. Secondary Structure C. Tertiary Structure D.Quaternary Structure copyright cmassengale 54 Primary Structure Amino acids bonded together by peptide bonds (POLYPEPTIDE) Amino Acids (aa) aa1 aa2 aa3 aa4 aa5 aa6 Peptide Bonds copyright cmassengale 55 Amino Acid Structure Primary = sequence of aa’s Secondary = forms pleated sheet, helix, or coil Tertiary = entire length of aa’s folded into a shape Quaternary = several aa sequences linked together ex. Hemoglobin, enzymes copyright cmassengale 57 Review 1. The monomers of proteins are? 2. What is one function of a lipid? 3. How are biomolecules put together? Condensation reaction or hydrolysis copyright cmassengale 58 Nucleic Acids copyright cmassengale 59 http://www.youtube.com/watc h?v=MnnfN5BIX7E&list=PLE7 B2BB1EB05699BC copyright cmassengale 60 Nucleic acids • Two types: a. Deoxyribonucleic acid (DNAdouble helix) b. Ribonucleic acid (RNA-single strand) • Nucleic acids are composed of long chains of nucleotides linked by dehydration synthesis. copyright cmassengale 61 Nucleic acids • Nucleotides include: phosphate group pentose sugar (5-carbon) nitrogenous bases: adenine (A) thymine (T) DNA only uracil (U) RNA only cytosine (C) guanine (G) copyright cmassengale 62 Nucleotide Phosphate Group O O=P-O O 5 CH2 O N C1 C4 Nitrogenous base (A, G, C, or T) Sugar (deoxyribose) C3copyright cmassengale C2 63 Nucleic Acid Structure • A nitrogenous base • 1-3 phosphate groups • Five carbon sugar FUNCTIONS • HEREDITARY INFORMATION (DNA/RNA) • ATP – CHEMICAL ENERGY copyright cmassengale 65 DNA Modeling copyright cmassengale 66 copyright cmassengale 67