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MINERALS Chapter 7 Minerals J Pistack MINERAL FUNCTIONS Inorganic Become part of body composition Represent 4% of total body weight Help to regulate bodily functions Essential to good health MINERAL CLASSIFICATIONS Major (macrominerals) More than 5 grams (approximately 1 tsp) in body Need 100 milligrams (1/50 tsp) intake daily Trace (microminerals)—less than 5 grams INTAKE REQUIREMENTS Major—100 milligrams (approximately 1/50 teaspoonful) or more per day Trace—less than 100 milligrams per day Ultratrace—less than 1 milligram per day MAJOR MINERALS Calcium Sodium Potassium Phosphorus Magnesium Sulfur Chloride CALCIUM Functions Provides hardness to bones and teeth Assists in the manufacture of ACH Serves as catalyst in muscle contractions Performs as catalyst in blood clotting AIs (adequate intake) Ages 19 to 50 years: 1000 milligrams Older than 50 years: 1200 milligrams UL (upper level)—2500 milligrams for adults CALCIUM SOURCES Animal products—milk, sardines, clams, oysters, salmon Plant products Rhubarb, spinach, greens, broccoli Cooking increases availability Fortified foods CALCIUM DEFICIENCIES Osteoporosis—bone mineral density (BMD) Greatest risk—postmenopausal, faircomplexioned white women Result—fractures Spine Hip Forearm (sentinel event) Two factors affecting bone health and growth Smoking Alcohol consumption CALCIUM DEFICIENCIES (CONTINUED) Tetany—MEDICAL EMERGENCY Low ionized calcium in blood (hypocalcemia) Diagnostic signs Chvostek sign—tapping over facial nerve twitch of the facial muscles Trousseau sign—B/P cuff pressure spasms of the forearm and hand CALCIUM TOXICITY Hypercalcemia Caused by diseases, usually not diet Can cause calcium deposits in soft tissues Milk-alkali syndrome Recent causes: excessive calcium carbonate ingestion to prevent osteoporosis PHOSPHORUS FUNCTIONS Calcium phosphate provides hardness to bones and teeth Component of DNA and RNA Contained in almost all enzymes Part of buffering compounds to maintain proper blood pH PHOSPHORUS DEFICIENCY AND TOXICITY Deficiency Uncommon due to diet in healthy person Drug interactions, disease, starvation Toxicity Cow’s milk in very young infants Potassium phosphate laxatives and enemas SODIUM FUNCTIONS AND SOURCES Functions Maintains fluid balance Helps transmit impulses along nerves and muscle fibers Sources Table salt—2 grams per teaspoonful Milk products, processed foods, some vegetables POTASSIUM FUNCTIONS AND SOURCES Functions Helps to control fluid balance Helps transmit impulses along nerves and muscle fibers Present in all plant and animal cells Fats, oils, and white sugar have negligible amounts POTASSIUM DEFICIENCIES Alkalosis Potassium-wasting diuretics Related to diet only in severe proteinenergy malnutrition Losses due to diarrhea, vomiting, laxative abuse Over hydration with plain water by perspiring athletes Increased losses in urine, stool, or sweat POTASSIUM TOXICITY Rarely caused by diet Diseases—diabetes, burns, crushing injuries Correct administration of intravenous potassium critical to health MAGNESIUM FUNCTIONS Associated with ADP and ATP in energy metabolism Aids in transmission of nerve impulses Influences cardiac and smooth muscle contractility MAGNESIUM SOURCES Green vegetables (magnesium is a part of the chlorophyll molecule) Coffee, tea, cocoa MAGNESIUM DEFICIENCY AND TOXICITY Deficiency Malabsorption disorders—vomiting or diarrhea Excessive alcohol use with poor nutrition Chronic diuretic use Diabetes Toxicity usually doesn’t build except for kidney disease SULFUR Adult body contains approximately 175 grams Component of cytoplasm of every cell. Found in hair, skin, and nails; contributes to their shape Component of thiamin, biotin, insulin, heparin, and the amino acids methionine and cysteine. Combines with toxins to neutralize them. CHLORIDE Major role in maintaining fluid and acid– base balance 88% is found in extracellular fluids— stomach 12% is found in intracellular fluids Released by white blood cells Mostly absorbed through the small intestine Excreted primarily by kidney as a result of sodium regulation TRACE MINERALS Iron Iodine Fluoride Zinc Selenium Chromium Copper Manganese Cobalt Molybdenum ULTRATRACE Arsenic Boron Nickel Silicon Vanadium These appear in the UL tables but RDAs or AIs are not determinable IRON Essential Primary in formation of hemoglobin storage form in body is ferritin Selectively absorbed IRON DEFICIENCY Most significant worldwide deficiency Groups at risk: infants, young children, adolescents, childbearing women 30%–50% post bariatric patients IRON TOXICITY Poisoning—most common cause of pediatric poisoning in United States Hemochromatosis - is an inherited blood disorder that causes the body to retain excessive amounts of iron Cooking in iron pots IODINE Found in iodide form in the body Average adult body contains 15–20 mg 70%–80% found in thyroid gland Main function—synthesis of thyroid hormones Intake from saltwater shellfish, fish, seaweed FLUORIDE Major contribution to human health relates to its role in preventing dental caries Contained in public U.S. drinking water Overdose rare—large volumes of instant tea or secretive eating of toothpaste with fluoride ZINC Adult humans contain 1.5 to 2.5 grams Found in all tissues, organs, and body fluids 86% in skeletal muscle and bones Abundant in central nervous system, where it affects transmission of impulses Essential for tissue growth because it synthesizes DNA/RNA ZINC DEFICIENCY In children Growth retardation Skeletal abnormalities Delayed sexual maturation In adults Alopecia Loss of taste sensation Poor wound healing Impaired immunity ZINC TOXICITY Swallowed coins that released zinc into the body Overuse adhesive of zinc-containing denture COPPER Found in all body tissues and most secretions Involved in hemoglobin synthesis and cell respiration Required for melanin pigment formation COPPER DEFICIENCY Occur from Taking medications that decrease stomach acidity Consuming zinc supplements—typically 40 milligrams or more per day Gastrointestinal diseases causing malabsorption Some kidney diseases increase copper loss Long-term complication of bariatric surgery Cause Bone abnormalities Impaired immune function Depigmentation of the skin and hair COPPER TOXICITY Wilson disease - is a rare inherited disorder that causes excess copper to accumulate in the body. Steadily increasing amounts of copper circulating in the blood are deposited primarily in the brain, liver, kidneys, and the cornea of the eyes. WD is fatal if it is not recognized and treated SELENIUM Highest concentrations occur in the thyroid gland, kidneys, liver, heart, pancreas, and muscle Integral to more than 25 enzymes that primarily function as antioxidants SELENIUM TOXICITY AND DEFICIENCY Rare in meat-eating humans with following exceptions: Taking phenylketonuria formulas Receiving parenteral nutrition as sole source of nutrients Consuming ketogenic diets – diets that give rise to ketone bodies in metabolism. SELENIUM DEFICIENCY Signs and symptoms Poor growth Muscle pain and weakness Depigmentation of hair and skin Whitening of nail beds CHROMIUM High concentrations are found in the kidney, liver, muscle, spleen, heart, pancreas, and bone Vitamin C may enhance absorption Antacids and phytate (A phosphoruscontaining compound that binds with minerals in the gastrointestinal tract and decreases their bioavailability which decreases absorption) CHROMIUM DEFICIENCY AND TOXICITY Individuals receiving parenteral nutrition without chromium have shown these signs of deficiency: Weight loss Peripheral neuropathy Impaired glucose utilization High plasma levels of free fatty acids Toxicity can cause Liver dysfunction/failure Anemia MANGANESE The body contains 10 to 20 milligrams of manganese Found in highest concentrations in the bones, liver, pancreas, and kidneys Involved in the formation of bone and cartilage MANGANESE DEFICIENCY Signs and symptoms Dermatitis Decreased growth of hair and nails Changes in hair color COBALT Necessary for red blood cell formation ULTRATRACE MINERALS Molybdenum—binds to copper, thought to diminish copper toxicities effects such as in Wilson disease Arsenic Boron Nickel Silicon Vanadium OTHER MINERALS THAT AFFECT HEALTH Aluminum Lead Mercury MINERAL SUPPLEMENTATION Most beneficial healthy minerals can be supplemented by food intake If supplementation is necessary with medication, make sure it meets daily requirements—not too much, little Make sure to tell health care providers what supplements you take