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Integrative Medicine in
Practice
Rachel Schneyer LAc, MS,
FABORM
Indole-3-Carbinol and Cancer
• Impact to metabolic pathway
via food therapy on disease,
such as 1995 study on
Brussel sprouts and colon
cancer (Nijhoff WA et al,
Carcinogenisis. 1995)
•Now to individualize…
Pathology + Individual = Treatment
• Genetic factors
• Assimilation/Detoxification
• Environmental factors:
Epigenetics
• Stress assay: Biofeedback,
Salivary panels
Conventional + Traditional = Broad Spectrum Care
The Era of Functional Medicine
• Some… carry polymorphisms that are
most important in determining the
outcome of {one’s} health history.
Administration of cofactors to these
polymorphic genes can restore activity
to normal levels.
• Ames et al (Am Journal of Clinical
Nutrition. 2002; 75: 616-58.)
MTHFR
• Errors in Folic acid metabolism & impact
on homocysteine
• Low Folate status may lead to
cardiovascular events, dementia,
increased clotting (cited in miscarriage)
and depression.
Prevention as Medicine
“The Superior Physician treats the patient
in wellness,
The Inferior Physician in disease.”
-Nei Jing
“Food for Thought”
• How to merge prevention with managed
care?
Can technology provide tools to quantify
one’s prevention effort?
Elements of Daily Focus
• Glycemic Control & Stress Response
• Circadian Rhythm (linked to antioxidant
status)
• Movement as medicine
Influences on Stress
• Jacobs GD: The Physiology of mindbody interactions: the stress response
and the relaxation response. J Altern
Complement Med. 2001.
Acupuncture and Stress
• Michael Hollifield et al “Acupuncture
for PTSD: A randomnized controlled
pilot.” Journal of Nervous and Mental
Disease, 2007.
• Acupuncture demonstrated as equally
useful to cognitive-behavioral therapy.
Applied technology
• MRI study demonstrated acupuncture
has measurable impact on brain areas
known to respond to opiates.
• Pariente J. et al. Neuroimage, 25. 1161 1167 (2005).
Reproductive Medicine
• “Changes in serum cortisol and prolactin
associated with acupuncture during IVF”
-Magarellii, PC et al Fertil Sterility 2009.
• “Beneficial changes in serum levels of stress
hormones while undergoing IVF, with higher
rates of pregnancy and live birth”
Integration of Pharma and Herbal
medicine
• John Chen “Chinese Medical Herbology
and Pharmacology”
• www.naturaldatabase.com
• *Details interaction/research validity
NIH funding on Tumeric
• Reduces beta-amyloid protein
• Cox-2 inhibitor
• Tumor inhibition
Tumeric
Four Clinical trials span arthritis, cancer, and
Alzheimer’s
Food for Thought
• How might data on individual variance
reshape patient care?
• How can technology provide access to
experts, education and social networks?
Chinese Medical Theory
• Prenatal
Reserves
“Finite”
Genetic
Makeup
• Postnatal
Reserves
Nutrition &
Assimilation
Clinical Assessment
• Qualitative
– Elimination diets
– Subjective
• Quantitative
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Holistic stool
Food intolerance
Stress index
Intestinal permeability