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“Possible Side Effects Include…”: Accutane Allison Boyle Overview • Accutane (Isotretinoin) is a prescription drug used to treat recalcitrant nodular acne if other treatments have failed. (generally a final effort) • This treatment is very controversial due to the many severe side-effects that could occur. • This pill is taken every day, but, unlike some pills, when one is missed you do NOT double up doses. This must be taken with food. Overview (cont.) • Blood tests are mandatory every month to regulate the body (liver) • One is required to take the iPLEDGE Program quiz before renewing prescriptions • This treatment usually lasts between 4-6 months • If acne is not gone after 6 months a second session on the drug may be necessary; however, a minimum 6 month period between doses • For more information please visit: https://www.ipledgeprogram.com/Default.aspx (iPLEDGE website) What it does! • This is a form of vitamin A that reduces the amount of oil (sebum) released by oil glands in the skin. • Decreases the cell buildup that causes whiteheads and blackheads • Kills acne bacteria within the skin • Reduces inflammation Things to Avoid While on Accutane • • • • • • Pregnancy Giving blood Breastfeed Other medications Cosmetic Procedures Drive at Night (until you know whether the medication has affected vision) • Sunlight/Ultraviolet Lights • Do NOT Share • Must be on 2 forms of birth control (females) • Consent to constant pregnancy tests to prevent birth defects from taking place • Mandatory blood tests every month • iPLEDGE quizzes • Can NOT donate blood while on Accutane or 30 days after treatment is ended • SUNSCREEN because sunburn is a very high risk Not So Serious Side Effects • Red, cracked, sore lips • Dry skin • Nosebleeds • Peeling skin • Slowed healing of cuts or abrasions of any kind • Increased sensitivity to the sun • • • • Dry eyes Dry nose Allergic Reactions Skin Problems Serious Side Effects • Mental Health Problems (depression, psychosis, suicide) • Life-Threatening Birth Defects • Seizures • Yellowing of the skin or eyes (caused by liver) • Swelling (miscellaneous places) • Serious Brain Problems • • • • Abdominal Problems Vision Problems Hearing Problems Bone and Muscle Problems • Blood Sugar Problems (Diabetes) Miscellaneous Costs… • Dermatologist Appointments (with or without insurance) • Blood Tests • The Medication Itself • Lotions • Altogether, the costs are extremely high. Being on this Pill • Like anyone else would say, this is a very dangerous pill, and it took a lot of time to make this decision, but overall I believe I made the correct choice. I took this for 6 months and my acne problem has subsided. I had to get constant blood and pregnancy tests to protect me from dangerous side effects. In addition, my body’s physiology changed dramatically. Being on this Pill (cont.) • My physiology changed due to the fact that my skin became extremely sensitive to both injury and sunburn in addition to the obvious dryness. I was forced to use 2 lotions specifically for my face in order to prevent constant peeling. My chap-stick received the name of my “glue stick” because it was a different, more potent brand than others. Being on this Pill (cont.) • From being on this pill I have learned that what you think about yourself is the most important thing. Several of my friends have approached me about potentially going onto this medication, and I strongly recommend it. Although the risks are large, the benefits for the user are priceless. THE END