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ABSTRACT
Drug Utilization Study of Prophylactic Antibiotics on
Benign Prostatic Hyperplasia Surgery
(A Study on the Department of Urology at Dr. Soetomo Teaching Hospital
Surabaya)
A Drug Utilization Study (DUS) of prophylactic antibiotics on Benign Prostatic
Hyperplasia surgery has been conducted at Dr. Soetomo teaching hospital, Surabaya.
The method of this study was non experimental, descriptive, and retrospective. The
objectives of this study were; (1) to observe the profile of prophylactic antibiotics used on
Benign Prostatic Hyperplasia (BPH) surgery; (2) to find the appropriateness of prophylactic
antibiotics used on patients with already non sterile urine before the surgery; and (3) to
observe the infection after BPH surgeries using prophylactic antibiotics.
Prophylactic antibiotics used in this study were: cefotaxime (used in 90,3%),
ciprofloxacin (used in 6,4%), and ceftazidime (used in 3,2 %). Over 17 patients with non
sterile urine, there were 4 cases of inappropriate use of cefotaxime on patients with urine
containing Pseudomonas. However, there were no signs of Surgical Site Infection (SSI)
following BPH surgeries, even though in most of the patients, significant elevation on
leukocytes count were occurred.
Keywords
: Drug Utilization Study (DUS), prophylactic antibiotics, Benign
Prostatic Hyperplasia (BPH)