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News You Can Use…
Pete Koval, PharmD
Megan Radigan, PharmD Candidate
Kira Letvak, PharmD Candidate
Cone Health Family Medicine
May 2015
News You Can Use…
This news cycles automatically
& IS INTENDED to provide
incentive to arriving early!
Thanks for coming early!
New Drug Approval
• Corlanor (ivabradine) received FDA
approval to reduce hospitalization from
worsening heart failure
• MOA: Selective and specific inhibition of the
hyperpolarization-activated cyclic nucleotidegated (HCN) channels (f-channels) within the SA
node of cardiac tissue resulting in disruption of If
ion current flow prolonging diastolic
depolarization, slowing firing in the SA node, and
ultimately reducing HR.
04/30/2015 FDA News and Events
New Drug Approval
• FDA approved
the first breathactuated (dry
powder)
albuterol rescue
inhaler, ProAir
RespiClick
04/30/2015 FDA News and Events
Statin Use in Hepatitis C
• Statins show benefit in Hepatitis C
compensated cirrhosis (retrospective
analysis)
• Statin use has generally been avoided in
people with liver disease because of
hepatotoxicity
• Statin use is associated with a 40% reduction
in the rate of hepatic decompensation and
death in this review
04/25/2015 Medscape Medical News
New Drug Approval
• FDA approves first generic
aripiprazole (Abilify®) to treat
schizoprenia and bipolar disorder.
04/29/2015 FDA News and Events
“New” Weight Loss Drug
Now Available
• Saxenda (liraglutide) weight loss
indication now available
• 0.6 mg/day increase to 3 mg daily by 5
weeks
• $1068 per month, insurance coverage???
04/23/2015 Corey Nahman