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News You Can Use… Pete Koval, PharmD Megan Radigan, PharmD Candidate Kira Letvak, PharmD Candidate Cone Health Family Medicine May 2015 News You Can Use… This news cycles automatically & IS INTENDED to provide incentive to arriving early! Thanks for coming early! New Drug Approval • Corlanor (ivabradine) received FDA approval to reduce hospitalization from worsening heart failure • MOA: Selective and specific inhibition of the hyperpolarization-activated cyclic nucleotidegated (HCN) channels (f-channels) within the SA node of cardiac tissue resulting in disruption of If ion current flow prolonging diastolic depolarization, slowing firing in the SA node, and ultimately reducing HR. 04/30/2015 FDA News and Events New Drug Approval • FDA approved the first breathactuated (dry powder) albuterol rescue inhaler, ProAir RespiClick 04/30/2015 FDA News and Events Statin Use in Hepatitis C • Statins show benefit in Hepatitis C compensated cirrhosis (retrospective analysis) • Statin use has generally been avoided in people with liver disease because of hepatotoxicity • Statin use is associated with a 40% reduction in the rate of hepatic decompensation and death in this review 04/25/2015 Medscape Medical News New Drug Approval • FDA approves first generic aripiprazole (Abilify®) to treat schizoprenia and bipolar disorder. 04/29/2015 FDA News and Events “New” Weight Loss Drug Now Available • Saxenda (liraglutide) weight loss indication now available • 0.6 mg/day increase to 3 mg daily by 5 weeks • $1068 per month, insurance coverage??? 04/23/2015 Corey Nahman
