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Key Terminology 2 Practicum of Health Science – Pharmacy Tech Program An unexpected and undesirable effect caused by a drug; different from a known side effect. Adverse Drug Reaction (ADR) One single, relatively large quantity of a substance, administered rapidly. Bolus Severe or fatal reaction by a patient to an agent for which the patient has become extremely sensitized. Anaphylactic Shock Agent that stops or inhibits the growth of bacteria (such as erythromycin) Bacteriostatic agent Procedures designed to prevent contamination of drugs, packaging, equipment, or supplies by microorganisms during processing. Aseptic preparation A substance that kills bacteria or inhibits its growth. Antibacterial agent Used to treat cancer by substituting in or blocking the use of essential nutrients and enzymes antimetabolites A drug that is able to kill or inhibit the growth of bacteria or other microorganisms. antibiotics Air pressure is greater inside of an enclosed area as compared to outside of enclosed area. This forces particulate matter to the outside of the enclosed area. positive air pressure An IV access into one of the major blood vessels central line Extraneous undissolved mobile substances, such as precipitate present in the parenteral products particulate matter Occurs when two or more chemical substances react and cause a significant change of one or more of the substances. chemical incompatibility A sterile, injectable medication (i.e. SC, ID, IM, IV) parenteral Condition or circumstance that mandates that a drug should not be given contraindication An infection acquired while the patient is in the hospital or healthcare facility nosocomial infection When a drug accumulates in the body faster than the body can metabolize or eliminate it cumulative effect A drug administered for therapeutic purposes into the body via the vascular system infusion Fluids used to dissolve drugs in solid form diluents Two or more drugs mixed together that cause either a physical, chemical or therapeutic change in the drug, and produce undesirable effects incompatible Long or short term IV feeding of high protein, high carbohydrate solutions to provide a patient’s total nutritional requirements Total Parenteral Nutrition (TPN) The substance that is dissolved in a solution solute Measure and documented evidence, providing a high degree of assurance that a specific process will consistently produce a product meeting its predetermined specifications and quality attributes process validation The complete destruction of microorganisms by heat or other method; free of microorganisms. sterilization The outcome that is expected for a particular disease, and whether there is a chance for recovery prognosis The substance used to dissolve another substance (the solute) solvent The set of activities used to assure that the process used in the preparation of sterile drug products leads to products that meet predetermined standards of quality quality assurance Some drugs are in a powder form because they are too unstable to be mixed until ready for use. Mixing the powder with a liquid is called reconstitution Under the skin; an injection administered under the skin subcutaneous The set of testing activities used to determine that the ingredients, components, and final sterile pharmaceuticals prepared meet predetermined requirements with respect to identity, purity, nonpyrogenicity, and sterility Quality Control Introduction of undesired microorganism or particles contamination Produced during a single manufacturing order batch Undesired effect of a drug side effect Results from a poison or a dangerous amount of a drug toxicity Invasion by an agent into the body infection An agent produced by the body in response to an antigen antibody An agent that destroys or inhibits microorganisms on inanimate objects disinfectant Common Medical Prefixes a-; an without; not ante before; forward anti against bi two; both brady slow contra against; opposite dys difficult; painful; bad en-; endo inside; within epi above ex out; outward hyper excessive; above hypo insufficient; below infra under; below inter between intra within iso equal; same micro small multi many; neo new multiple para beside; near per through peri around poly many; excessive post after, behind pre before semi half; one-half sub below; under Let’s review some Common Medical Abbreviations and Acronyms, and Common Pharmacy Abbreviations