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Chapter 16/18 Drugs/Alcohol Formula to Follow • No more 3drinks/occasion • No more than 2/wk • Drink on full stomach • Metabolize 1 drink/hour Bodies Defense • Taste bad • Throw up • Pass out Drug Use • Quick fix –Headache, stomach ache, fatigue, mood • Need to change lifestyle Drugs Defined • Substance alters biological process –Increase, decrease, start, or stop body process • Classified-biological effect –Diuretic, analgesic, stimulant How They Work • Drugs hook to cell protein receptors • Resemble natural chemical • Prevent or increase release neurotransmitters Side Effects • Unintended action • Drug binds to several cells Contraindication • Medical reason not to take a drug –Pregnant, age, taking another drug Route Administration • Ingest • Inhale • Inject • absorb Metabolism •Liver- destroys •Kidney/lungs-eliminate Effectiveness • Therapeutic Index- how safe – Effective dose(ED50)- effective in 50% – Lethal dose(LD50)- lethal dose in 50% • LD50/ED50 • Want large difference Legal Use • Prescription= $100 billion/yr • Non-prescription=$12 billion/yr • Most sold=psychoactive drugs –Sleeping, mood altering Printed Advertisement • Heavy regulated –Effectiveness, side effects, precaution, contraindications • TV and Internet –Little regulated