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For Women, for Life Estera™ Launch Tour 2004 For Women, for Life Women’s hormone health is • Complicated • Personal • Emotional • Scary! For Women, for Life BUT it is also: • Amazing • Important • Empowering • And there IS good news For Women, for Life SO… Get ready for a life changing experience! A Clinician’s Perspective: Integrative Therapies for Women Lori Blackner, D.Ph. Integrative Therapies — A 21st Century Women’s Revolution Women’s Health Educate yourself on your needs and how to meet them: – Balancing hormones – Managing metabolites – Dealing with symptoms Women’s Primary Health Concerns 33% Heart Health Lung Health Breast Health Colon Health Accidents Diabetes Pneumonia & Influenza Lung Conditions All Other Conditions 41% 5% 4% 3% 5% 3% 2% 4% National Vital Statistics Report, Vol 48, No. 11, July 24, 2000 Sex Hormones • Primary women’s hormones – Estrogen – Progesterone – Androgens – Gonadotropins Estera™ 1. Hormone Balance* 2. Estrogen Metabolites* 3. Phase Specific Symptoms* *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Proprietary, Patent-Pending Blend Genistein Pomegranate fruit Phytoestrogens support healthy hormone balance* Indole 3-carbinol Flax lignans Enzyme inducers help the body manage estrogen metabolites* *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Estera™ 1. Hormone Balance* 2. Estrogen Metabolites* 3. Phase Specific Symptoms* *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Women’s Phases Pre-menstrual years Childbearing years Peri-menopause Post-menopause stable variable drop What are our choices? 1. Do nothing different 2. Eat a healthy diet and exercise regularly 3. Nutritional supplements Estera™ 1. Hormone Balance* 2. Estrogen Metabolites* 3. Phase Specific Symptoms* *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Genistein • Most potent, active phytoestrogen • Genistein found in soy, but not all soy products contain genistein Chemistry Genistein Genistein has 40 times greater affinity for beta receptors which are found in: • Bones • Blood vessels • Central nervous system Genistein Helps maintain bone mineral density after 12 months* Ward's Triangle BMD 5 4 4 3 Placebo 2 Genistein 1 0 -1 -0.36 12 Months % change from basal % change from basal 5 Femoral Neck BMD 3.6 4 3 Placebo 2 Genistein 1 0 -1 -0.65 12 Months Morabito. J Bone Mineral Research. 2002 *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Pomegranate • One of the oldest natural remedies • High ORAC antioxidant • Source of flavonoids – 2.5% ellagic acid • Contains phytoestrogen compounds Estera™ 1. Hormone Balance* 2. Estrogen Metabolites* 3. Phase Specific Symptoms* *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Estrogen Metabolites • Estrogen produced by body, or obtained exogenously must be metabolized by the liver Estrogen Metabolites Daily Consumption • Studies show that daily intake of 6+ servings of cruciferous vegetables provides health benefits • Do YOU eat 6+ servings a day of cruciferous vegetables? Enzyme Inducers Indole 3-carbinol (I3C) – Cruciferous vegetables: broccoli, cabbage, kale, brussels sprouts Flaxseed lignans – Fiber portion of flaxseed – 20% lignans Estrogen Metabolites Urinary excretion of estrogen metabolites before and after indole 3carbinol (I3C) administration (95% CI). 2-hydroxyestrone (2OHE1) 7 16-alphahydroxyestrone (16aOHE1) 6.62 0.7 0.6 5 nmol/mmol creatinine nmol/mmol creatinine 6 4 3.332 3 2 1 0.569 0.5 0.421 0.4 0.3 0.2 0.1 0 0 Pre Post 7 days Pre Post 7 days Michnovicz JJ, Adlercreutz H, Bradlow HL. Changes in levels of urinary estrogen metabolites after oral indole-3- carbinol treatment in humans. J Natl Cancer Inst 1997;89:718-23. Estera™ 1. Hormone Balance* 2. Estrogen Metabolites* 3. Phase Specific Symptoms* *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Childbearing Years • Fluctuation in hormones – 70-90% of women experience PMS symptoms – Nervousness, irritability, fluid retention, breast tenderness, bloating, etc. Perimenopause • Hot flashes, vaginal dryness, occasional anxiousness, mild mood swings, decreased libido, fatigue •More common in European and North American women than in other populations • Of those with symptoms, 75% experience enough discomfort to seek relief North American Menopause Society. www.menopause.org Postmenopause • Health concerns – Heart health • Increased cardiovascular concerns – Blood flow, heart function, lipid levels – Bone health • Women lose about one-third of their bone mass between menopause and age 80 – Breast and uterine health • Increased concern with women’s age North American Menopause Society. www.menopause.org Women’s Health Educate yourself on your needs and how to meet them: – Balancing hormones – Managing metabolites – Dealing with symptoms Self Discovery Discover yourself! Talk to your sisters mother, grandmother and friends Your Choice SO… NOW IT’S UP TO YOU! The Estera Story TM • Patent-pending blend for 3 phases – Hormone balance* – Estrogen metabolite maintenance* • Each product addresses phase specific symptoms* • Standardized extracts • Clinically-effective dosages of key ingredients *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Estera™ Phase I Women’s Balance Formula • Targets healthy hormone balance* • Supports healthy estrogen metabolism* • Helps relieve common PMS symptoms* *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Estera™ Phase II Women’s Transitions Formula • Targets healthy hormone balance* • Supports healthy estrogen metabolism* • Helps relieve common perimenopause symptoms* *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Estera™ Phase III Women’s Maintenance Formula • Targets healthy hormone balance* • Supports healthy estrogen metabolism* • Helps maintain healthy systems affected by post menopause* *These products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Complementary Products Nutritionals Solutions (launch) Complementary Products TRA Childbearing years Perimenopausa Postmenopause LifePak® Women MarineOmega LifePak® Women MarineOmega LifePak® Prime MarineOmega Estera™ Phase II Estera™ Phase III CordyMax® Cortitrol® NightTime Formula ReishiMax GLp® CordyMax® Cortitrol® BioGinkgo® Bone Formula Transition Weight Control Postmenopause Weight Control Estera™ Phase I Cortitrol® Postpartum Weight Loss Official Launch Visit www.forwomenforlife.com