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For Women, for Life
Estera™
Launch Tour
2004
For Women, for Life
Women’s hormone health is
• Complicated
• Personal
• Emotional
• Scary!
For Women, for Life
BUT it is also:
• Amazing
• Important
• Empowering
• And there IS good news
For Women, for Life
SO…
Get ready
for a life
changing
experience!
A Clinician’s Perspective:
Integrative Therapies
for Women
Lori Blackner, D.Ph.
Integrative Therapies —
A 21st Century Women’s Revolution
Women’s Health
Educate yourself on your needs and how to
meet them:
– Balancing hormones
– Managing metabolites
– Dealing with symptoms
Women’s Primary Health Concerns
33%
Heart Health
Lung Health
Breast Health
Colon Health
Accidents
Diabetes
Pneumonia & Influenza
Lung Conditions
All Other Conditions
41%
5%
4%
3%
5%
3% 2%
4%
National Vital Statistics Report, Vol 48, No. 11, July 24, 2000
Sex Hormones
• Primary women’s hormones
– Estrogen
– Progesterone
– Androgens
– Gonadotropins
Estera™
1. Hormone Balance*
2. Estrogen Metabolites*
3. Phase Specific
Symptoms*
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Proprietary, Patent-Pending Blend
Genistein
Pomegranate fruit
Phytoestrogens support
healthy hormone balance*
Indole 3-carbinol
Flax lignans
Enzyme inducers help the
body manage estrogen
metabolites*
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Estera™
1. Hormone Balance*
2. Estrogen Metabolites*
3. Phase Specific
Symptoms*
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Women’s Phases
Pre-menstrual
years
Childbearing
years
Peri-menopause
Post-menopause
stable
variable
drop
What are our choices?
1. Do nothing different
2. Eat a healthy diet and exercise regularly
3. Nutritional supplements
Estera™
1. Hormone Balance*
2. Estrogen Metabolites*
3. Phase Specific
Symptoms*
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Genistein
• Most potent, active phytoestrogen
• Genistein found in soy, but not all soy
products contain genistein
Chemistry
Genistein
Genistein has 40 times greater affinity for
beta receptors which are found in:
• Bones
• Blood vessels
• Central nervous system
Genistein
Helps maintain bone mineral density after 12 months*
Ward's Triangle BMD
5
4
4
3
Placebo
2
Genistein
1
0
-1
-0.36
12 Months
% change from basal
% change from basal
5
Femoral Neck BMD
3.6
4
3
Placebo
2
Genistein
1
0
-1
-0.65
12 Months
Morabito. J Bone Mineral Research. 2002
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Pomegranate
• One of the oldest natural
remedies
• High ORAC antioxidant
• Source of flavonoids
– 2.5% ellagic acid
• Contains phytoestrogen compounds
Estera™
1. Hormone Balance*
2. Estrogen Metabolites*
3. Phase Specific Symptoms*
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Estrogen Metabolites
• Estrogen produced by body, or obtained
exogenously must be metabolized by the
liver
Estrogen Metabolites
Daily Consumption
• Studies show that daily intake of 6+
servings of cruciferous vegetables
provides health benefits
• Do YOU eat 6+ servings
a day of cruciferous
vegetables?
Enzyme Inducers
Indole 3-carbinol (I3C)
– Cruciferous vegetables:
broccoli, cabbage, kale,
brussels sprouts
Flaxseed lignans
– Fiber portion of flaxseed
– 20% lignans
Estrogen Metabolites
Urinary excretion of estrogen metabolites before and after indole 3carbinol (I3C) administration (95% CI).
2-hydroxyestrone (2OHE1)
7
16-alphahydroxyestrone
(16aOHE1)
6.62
0.7
0.6
5
nmol/mmol creatinine
nmol/mmol creatinine
6
4
3.332
3
2
1
0.569
0.5
0.421
0.4
0.3
0.2
0.1
0
0
Pre
Post
7 days
Pre
Post
7 days
Michnovicz JJ, Adlercreutz H, Bradlow HL. Changes in levels of urinary estrogen metabolites
after oral indole-3- carbinol treatment in humans. J Natl Cancer Inst 1997;89:718-23.
Estera™
1. Hormone Balance*
2. Estrogen Metabolites*
3. Phase Specific Symptoms*
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Childbearing Years
• Fluctuation in hormones
– 70-90% of women experience PMS
symptoms
– Nervousness, irritability, fluid
retention, breast tenderness,
bloating, etc.
Perimenopause
• Hot flashes, vaginal dryness, occasional
anxiousness, mild mood swings, decreased libido,
fatigue
•More common in European and North American
women than in other populations
• Of those with symptoms, 75% experience enough
discomfort to seek relief
North American Menopause Society. www.menopause.org
Postmenopause
• Health concerns
– Heart health
• Increased cardiovascular concerns
– Blood flow, heart function, lipid levels
– Bone health
• Women lose about one-third of their bone mass
between menopause and age 80
– Breast and uterine health
• Increased concern with women’s age
North American Menopause Society. www.menopause.org
Women’s Health
Educate yourself on your needs and how to
meet them:
– Balancing hormones
– Managing metabolites
– Dealing with symptoms
Self Discovery
Discover yourself!
Talk to your sisters
mother, grandmother
and friends
Your Choice
SO…
NOW IT’S
UP TO
YOU!
The Estera Story
TM
• Patent-pending blend for 3 phases
– Hormone balance*
– Estrogen metabolite maintenance*
• Each product addresses phase specific
symptoms*
• Standardized extracts
• Clinically-effective dosages of key ingredients
*These products have not been evaluated by the Food and Drug Administration. These products are not intended to
diagnose, treat, cure, or prevent any disease.
Estera™ Phase I
Women’s Balance Formula
• Targets healthy hormone
balance*
• Supports healthy
estrogen metabolism*
• Helps relieve common
PMS symptoms*
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Estera™ Phase II
Women’s Transitions Formula
• Targets healthy hormone
balance*
• Supports healthy estrogen
metabolism*
• Helps relieve common
perimenopause symptoms*
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Estera™ Phase III
Women’s Maintenance Formula
• Targets healthy hormone
balance*
• Supports healthy estrogen
metabolism*
• Helps maintain healthy
systems affected by post
menopause*
*These products have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
Complementary Products
Nutritionals
Solutions
(launch)
Complementary
Products
TRA
Childbearing years
Perimenopausa
Postmenopause
LifePak® Women
MarineOmega
LifePak® Women
MarineOmega
LifePak® Prime
MarineOmega
Estera™ Phase II
Estera™ Phase III
CordyMax®
Cortitrol®
NightTime
Formula
ReishiMax GLp®
CordyMax®
Cortitrol®
BioGinkgo®
Bone Formula
Transition Weight
Control
Postmenopause
Weight Control
Estera™ Phase I
Cortitrol®
Postpartum
Weight Loss
Official Launch
Visit
www.forwomenforlife.com