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Acute Chest Pain “Can I go back to sleep?” Dr. Hussam Al-Faleh Residents Course Outline Clinical presentations Causes of chest pain Clinical aids to diagnose Ischemic CP summery It’s so painful I can’t breath! 25yr old male with CP for 3 days Sharp, central, worse with inspiration, and lying down, better sitting up, No relation to exertion H/o URTI 7 days ago No RF BP 110/70, HR 100 bpm, triphasic pericardial rub Wide spread ST elevation, PR depression Diagnosis: Pericarditis The Sky is falling 40yr old female CP for 3 months Can not be described, all over the chest and both shoulders, radiates to her head, continuous, not ↑ exertion, but exacerbated with emotional distress Divorced and physically abused by daughter No RF Normal PE and ECG Diagnosis: Psychogenic chest pain Nothing is wrong with me! 63yr male CP for last month Central burning, non radiating occurring only on exertion , relieved with rest. HTN PE & ECG Normal Diagnosis: Typical anginal pain I am like no other! 45yr male Upper back pain for 2 weeks Never occurs at rest or change in posture, and provoked by effort relived with rest H/o Premature atherosclerosis Normal PE & ECG Diagnosis: very suspicious for ischemic pain Causes of Chest pains Panjue et al JAMA 1998;280,14 Goals of CP assessment 1- Need to r/o serious causes of chest pain “ what is the chance that my patient will die due his underlying condition” 2- Need to refer for further testing i.e EST, V/Q scan , Angiogram etc.. 3- If cause of CP is not serious how can i help? eg. NSAIDS for MSL CP, PPI trial/GI consult for Reflux Risk stratification 1. 2. 3. High risk AMI, High risk UA Lyse or cath NSTEMI, LBBB, High risk UA Admit to CCU Low risk UA, Non ischemic pain admit to ward or see as outpatient History Chest Pain description: Vital signs/ECG Location and radiation Character Onset and duration Aggravators and relievers Severity Associated symptoms Panjue et al JAMA 1998;280,14 Panjue et al JAMA 1998;280,14 Typical/Atypical CP Typical: 1. Substernal 2. Burning/heavy/squeezing 3. ↑ by exertion ↓ rest or NTG If clinically angina , classify: Risk factors Age : males ≥45, females ≥55 Gender DM Dyslipidemia HTN Smoking Family history of Premature CAD: males ≤55 females ≤65 Metabolic syndrome Physical exam Vitals, Vitals, Vitals BP (measure both sides) Pulses paradoxicus Heart rate (tachy/bradycardia) Respiratory rate Fever O2 Sat Physical exam CVS exam: - JVP Carotid bruit Palpation of chest wall (where is the pain?) Extra Heart sounds (S3 or 4) Murmurs (eg, early diastolic, ) Pericardial rub Physical exam Chest exam: - - Trachea Breath sounds Abdomen: - Tenderness Investigations ECG: - - NORMAL ECG DOES NOT ROLE OUT ISCHEMIA Serial ECG’s Always compare to an old ECG ST ↑ (localized vs. Wide spread) ST ↓ T wave inversion (location and symmetry) or peaking ECG (cont.) - - Q waves (new) New conduction defects (LBBB/RBBB) Voltage/electrical alternans/Tachycardia PE patterns (Q1 S3 T3), RBBB, Other investigations (PRN) Depending on Hx/PE CBC D-dimers ABG’s CXR Troponins I & T Most sensitive and specific cardiac markers Rise 3-12hr after onset of CP Peak I (24hr), T (12hr-2 days) Return to normal 5-14 days Has both diagnostic and prognostic values Sample at baseline and after 6-8hr Conclusion History and physical are corner stones in diagnosis of Chest pain Ensure that patient is stable before taking a detailed history Serial ECG’s and cardiac enzymes for selected patients