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Animals Tissue Development Day 0: Conception Sperm (n) fertilizes the egg (n) The cell is now called a Zygote now Diploid in number (2n) Day 1: First Cleavage 1 cell becomes 2 cells through a process called mitosis Day 2: Second Cleavage 2 cells becomes 4 cells Day 3: 4 cells becomes 8 cells can test fore genetic diseases as early as this stage if conception was IVF (in vitro fertilization) Day 4: 16 – 32 cells Solid ball of cells is called a morula mass Day 6 - 7: Blastocyst attaches itself to the endometrium (the lining of the uterine) = Implantation Blastocyst secretes HCG (human chorionic gonatotropin) • Pregnancy tests measure the amount of this hormone • Stimulates the release of estrogen and progesterone preventing menstration • Causes “Morning Sickness” in some women Day 7 - 10: Gastrulation: major cellular reorganization into 3 germ (tissue) layers • Ectoderm – (outer) skin, nervous system • Mesoderm – (middle) muscles and bones • Endoderm – (inner) lining of gut and internal organs All the cells have the same DNA, however, different cells begin to “turn on” or “express” different genes to become different organs Embroyonic Layers 1. Ectoderm diploblastic 2. Endoderm triploblastic 3. Mesoderm Day 10 - 14: Pregnancy is established: • Chorion (placenta) begins to form • Amniotic fluid begins to form • Embryo starts to form from embryonic disc • Yolk sac – makes blood & germ cells Day 15 - 21: Emergence of a vertebrate body plan: Primitive streak: • Neural groove – future spinal cord and brain (CNS) • Somites – bands of tissue to become muscle & bone • Pharyngeal arches – future neck, face, mouth, nose Day 21… Week 3 – Week 8 (Embryo): Development of all organ systems Week 8 Embryo – is now called a Fetus: Gender differentiation begins SRY gene present and functioning = ovaries—testes; labium—scrotum; cliteris—penis Pharyngeal arches The diagram above shows a developing worm embryo at the four-cell stage. Experiments have shown that when cell 3 divides, the anterior daughter cell gives rise to muscle and gonads and the posterior daughter cell gives rise to the intestine. However, if the cells of the embryo are separated from one another early during the four-cell stage, no intestine will form. Other experiments have shown that if cell 3 & cell 4 are recombined after the initial separation, the posterior daughter cell of cell 3 will once again give rise to normal intestine. Do you think… - Cell 4 transfers genetic material to cell 3, which directs the development of intestinal cells? - Cell 3 passes an electrical signal to cell 4, which induces differentiation in cell 4? - The plasma membrane of cell 4 interacts with the plasma membrane of the posterior portion of cell 3, causing invaginations that become microvilli? - A cell surface protein on cell 4 signals cell 3 to induce formation of the worm’s intestine? Cells communicate with each other in a variety of ways - most of which involves proteins embedded in their cell membranes. As it turns out, there is a protein in the worm’s cell #4 that signals cell 3 to begin intestinal formation. Teratogen: an agent or factor that causes malformation of an embryo Chordata • Vertebrates – fish, amphibians, reptiles, birds, mammals – internal bony skeleton hollow dorsal • backbone encasing spinal column • skull-encased brain Oh, look… your first baby picture! nerve cord becomes brain & spinal cord becomes gills or Eustachian tube pharyngeal pouches becomes tail or tailbone postanal tail becomes vertebrae notochord Animal Evolution exoskeleton backbone segmentation endoskeleton True coelom body cavity asymmetry radial symmetry Independent cells multicellularity Ancestral Protist bilateral symmetry tissues Animal Evolution Cnidaria Porifera sponges jellyfish Nematoda Platyhelminthes Echinoderm Arthropoda Mollusca segmented insects spiders roundworms Seastar mollusks worms flatworms exoskeleton Annelida Chordata vertebrates backbone segmentation endoskeleton True coelom body cavity asymmetry radial symmetry Independent cells multicellularity Ancestral Protist bilateral symmetry tissues Embroyonic Layers 1. Ectoderm diploblastic 2. Endoderm triploblastic 3. Mesoderm Body Cavity How much is the digestive tract separated from the rest of the body? ectoderm mesoderm endoderm acoelomate ectoderm mesoderm endoderm pseudocoelomate pseudocoel • 3 body layers – ectoderm – mesoderm – endoderm ectoderm mesoderm coelom cavity coelomate endoderm Embroyonic Layers 1. Ectoderm 2. Endoderm 3. Mesoderm What embryonic layers develop into these structures? 1. Skin/epidermis Skin/Epidermis 7. Lungs Lungs 13. Nerves Nerves 2. Muscles Muscles 8. Neural Neuraltube tube 14. Liver Liver 3. Kidneys Kidneys 9. Reproductive Reproductiveorgans organs 15. Hair Hair 4. Spinal Spinal cord cord 10. Notochord Notochord 16. Bones 5. Intestines Intestines 11. Blood vessels 17. Eye 6. Heart Heart 12. Tooth Tooth enamel enamel 18. ?? sequence of stages during embryogenesis Using these terms, answer the questions below: Fertilization - Zygote Cleavage - Embryo Blastula Gastrulation Neuralization a. This process establishes the primary germ layers b. Cells migrate over the dorsal lip of the blastopore c. number of cells increases, but there is no increase in total cell mass and there is little or no differentiation d. Two haploid cells fuse to form a diploid cell sequence of stages during embryogenesis Using these terms, answer the questions below: Fertilization - Zygote Cleavage - Embryo Blastula Gastrulation Neuralization a. This process establishes the primary germ layers Gastrulation b. Cells migrate over the dorsal lip of the blastopore Blastula c. number of cells increases, but there is no increase in total cell mass and there is little or no differentiation Cleavage d. Two haploid cells fuse to form a diploid cell Fertilization