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Biology Mitosis notes Unicellular organisms - asexual reproduction Multicellular organisms- growth & repair. Figure 10–4 The Cell Cycle Section 10-2 G1 phase M phase S phase G2 phase Cell Cycle • Interphase - the longest part of the cell cycle: growth, metabolism & preparation for division occurs. • Mitosis- the division of the nucleus. • Cytokinesis - the division of the cytoplasm. Interphase (In-between) • Part of the cell cycle, not a part of Mitosis. • Longest part of the cell cycle • Growth, metabolism, & preparation for division occurs. • Chromosomes are replicated. The Steps of Mitosis • PMAT • Mitosis is the division of the nucleus producing two cells with the same number of chromosomes. Prophase (Preparing) • Longest phase of mitosis • Nuclear envelope & nucleous disappears. • Chromosomes become visible. • Centrioles (animal cell) form and move to opposite poles of cell • Spindle fibers form from centrioles, cross cell and attach to the chromosomes. Metaphase (middle) Chromosomes line up in the middle of the cell. Spindles are attached to them. Anaphase (Apart) • Spindle fibers begin to shorten. • This pulls chromosomes apart. • Chromosome halves are now referred to as chromatids. Telophase (Two cells) • Chromatids reach poles. • Chromosomes become chromatin. • Spindle fibers break down. • Nucleolus and nuclear envelope appear. Cytokinesis (happens after telophase) • Division of cytoplasm • In animal cells: cell membrane continues to pinch in until two cells are formed • In plant cells: cell plate forms in center of cell and eventually splits cells • At the end of cell division, two new “daughter” cells are produced.