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Meiosis Unit – Cell Reproduction Biology Meiosis • Process of cell division that reduces the number of chromosomes to half • Produces haploid cells called gametes • Gametes are…. • Each gamete contains 23 chromosomes Egg cell Sperm cells Meiosis One replication, two divisions Interphase I (G1, S, G2) • chromosomes replicate to produce homologous pairs (sister chromatids) Meiosis I • homologues separate Meiosis II • sister chromatids separate Meiosis I Interphase • cell grows to mature size • copies its DNA Meiosis I Prophase I • DNA coils tightly into chromosomes • Spindle fibers appear • Nucleus disappears Meiosis I Metaphase I • Tetrads line up in the middle • They line up randomly with respect to the poles of the cell. Meiosis I Anaphase I • Each homologous chromosome (consisting of two chromatids) moves to opposite sides of the cell Meiosis I Telophase I and Cytokinesis I • Chromosomes reach opposite sides of cell • Cytoplasm divides resulting in 2 cells Prophase II • DNA coils tightly into chromosomes • Spindle fibers appear • Nucleus disappears Meiosis II Metaphase II • Chromosomes move to middle of each cell Meiosis II Anaphase II • Chromatids separate and move to opposite poles of each cell Meiosis II Telophase II and Cytokinesis II • A nuclear membrane forms around the chromosomes in each of the 4 cells • DNA unwinds to chromatin form Meiosis II Results in four new cells, Each cell contains half of the original cell’s number of chromosomes Meiosis II A Comparison Mitosis And Meiosis