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(1.2) Cell Division - Mitosis (p28-31) Cell Cycle In the cell cycle, a precise sequence of events leads to the creation of new cells. The events are: • Interphase • Mitosis (including prophase, metaphase, anaphase, and telophase) • Cytokinesis Creating New Cells- the steps Page p29 Figure 1.10 Creating New Cells- the steps Remember the steps! Interphase Prophase Metaphase Anaphase Telophase Cytokinesis I Prefer Mice And Talking Cats New animal cells are created during the cell cycle. The nucleolus, is a structure composed of proteins and nucleic acids found within the nucleus. Chromatin condenses to form chromosomes. Copyright © 2010 McGraw-Hill Ryerson Ltd. New animal cells are created during the cell cycle. Replicated chromosomes are also called sister chromatids. In animal cells, a pair of organelles called centrioles move to each end of the cell, forming poles of the miotic spindle. Copyright © 2010 McGraw-Hill Ryerson Ltd. New animal cells are created during the cell cycle. Each chromosome is connected to a the spindle fibre at its centromere. Copyright © 2010 McGraw-Hill Ryerson Ltd. New animal cells are created during the cell cycle. Copyright © 2010 McGraw-Hill Ryerson Ltd. New animal cells are created during the cell cycle. Copyright © 2010 McGraw-Hill Ryerson Ltd. New animal cells are created during the cell cycle. Copyright © 2010 McGraw-Hill Ryerson Ltd. Cell Cycle Diagrams • Interphase • Prophase • Metaphase MITOSIS • Anaphase • Telephase • Cytokinesis Mitosis Diagrams & Images Cell Division – Uncontrolled! • If a cell ignores a signal to stop dividing, unchecked cell growth can result. Over time, the newly divided cells form a mass called a tumour. • A mutation (a permanent change in a cell’s DNA) is what causes the cells to ignore the “stop” signals. • Cancer cells differ from normal cells in shape, size, and content. Cancer Cells • Benign tumour cells tend to look normal. • Cancer cells (malignant tumour cells) look much more “unusual”. Copyright © 2010 McGraw-Hill Ryerson Ltd. Normal vs Cancerous Cell Division Copyright © 2010 McGraw-Hill Ryerson Ltd. Cancer Cells Cancer Cells Drinking causes liver cancer Recap – Videos Mitosis(1) Mitosis(2) Classwork WORKSHEET: “Mitosis” & “Getting to Know the Cell Cycle” NOTE: BIOLOGY TEST #1 - Fri. May 17