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Youtube links to watch • http://www.youtube.com/watch?v=gwcwSZ IfKlM • http://www.youtube.com/watch?v=lpAa4T WjHQ4 10.2 Eukaryotic Cell Cycle • Cell cycle--repeating phases of : – Growth (Interphase) – DNA replication (Interphase) – preparation for cell division (Interphase) – division of the nucleus and cytoplasm (cell division—mitosis & cytokinesis) Interphase • G1: cell grows to mature size, makes more organelles • S: chromosomes replicate • G2: cell continues to grow and prepare to divide; cell forms specialized structures that help the cell divide (ex. microtubules) 2 Stages of Cell Division: 1. Mitosis: the process in which a cell’s nucleus divides into 2 identical daughter nuclei. *Begins after interphase and ends before cytokinesis. *PMAT (4 phases) 2. Cytokinesis: cytoplasm division (and organelles) *Cell physically splits into 2 MITOSIS — 4 phases (PMAT): 1. PROPHASE • chromosomes condense (coil up and become visible under a microscope). • Centrosome helps to assemble spindle fibers. • a pair of centrioles migrate to each pole of the cell (animal cells only). • nuclear envelope and nucleolus break down (disappear). 2. METAPHASE • spindle fibers arrange chromosomes in the middle of the cell along the equator of the cell. • spindle fibers link the chromatids of each chromosome to opposite poles. 3. ANAPHASE • centromeres divide • spindle fibers pull sister chromatids towards opposite poles. • result =each pole has a full set of chromosomes. 4. TELOPHASE • 2 daughter nuclei are formed • reverse of prophase: nuclear envelopes form around each set of chromosomes; chromosomes uncoil to form a loose mass of chromatin; spindle fibers break down (disappear). CYTOKINESIS • animal cell…cell membrane grows into the center of the cell at the center of the parent cell and divides it into 2 daughter cells of equal size; called a cleavage furrow • plant cells…form a cell plate (from the parent cell wall).