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Animal Systems The Digestive System Higher Organisms All have same basic challenges *obtain nutrients *distribute nutrients through body *void wastes *respond to environment *reproduce All have similar ways of dealing with challenges – the body systems The Digestive System Not need by autotrophs, only heterotrophs Digestion: Large food molecules break down into simpler molecules absorbed by body for cell activities Simple Animals: intracellular digestion – food vacuoles ex. Hydra – encloses captured food in vacuole where lysosomes containing digestive juices fuse & break down food The Digestive System Complex Animals: extracellular digestion – digestive tract (gastrovascular cavity) ex. Grasshopper – food passes through specialized regions of gut mouth esophagus crop (storage organ) stomach intestine rectum anus The Human Digestive System Structures *Mouth *Esophagus *Stomach *Small intestine *Large intestine *Accessory Organs - salivary glands, pancreas, liver, gall bladder 4 Kinds of Molecules Broken Down 1. Starch (sugar) 2. Proteins 3. Fats 4. Nucleic acids (RNA, DNA) 1st Stop: The Mouth a.k.a. Oral Cavity Ingestion – food enters oral cavity Mechanical Digestion – chewing (mastication) – bolus Chemical Digestion – saliva * secreted by salivary glands (1st accessory organ) * contains salivary amylase – enzyme breaks down starch into maltose (2 glucose molecules: disaccharide) Bolus moves through pharynx into esophagus Pharynx – both food & air pass through *epiglottis – flap of connective tissue that closes when food swallowed to prevent from going into trachea Esophagus – tube-like organ that moves bolus from mouth to stomach *peristalsis – wave-like contractions (involuntary) move bolus down 2nd Stop: The Stomach Thick muscular sac that: - temporarily stores ingested food - partially digests proteins - kills bacteria Chemical Digestion Gastric juices - secreted by parietal cells (epithelial) - contains: 1. HCl – (pH = 2) kills most bacteria - stomach cells secrete mucous for protection 2. pepsin (pepsinogen) – proteins smaller peptides - activated by low pH (HCl) The Stomach Mechanical Digestion - churning action - bolus now called chyme - enters small intestine through the pyloric sphincter 3rd Stop: The Small Intestine 3 Regions – 23 ft long in avg. man *Duodenum – connects stomach to jejunum *Jejunum – connects duodenum to ileum *Ileum – connects jejunum to large intestine Chemical Digestion - All 4 kinds of molecules completely digested - intestinal walls secrete: 1. Maltase, Lactase, Sucrase – carbs simple sugars 2. Peptidases – proteins peptides Small Intestine Chemical Digestion The pancreas (2nd accessory organ) plays large role in chemical digestion - secretes enzymes through pancreatic duct 1. Pancreatic amylase – starch disaccharides 2. Trypsin/Chymotrypsin – proteins dipeptides 3. Pancreatic lipase – lipids (fats) fatty acids & glycerol 4. Ribo-/Deoxyribonucleases – nucleic acids nucleotides - secretes bicarbonate through duct *neutralizes acid coming into small intestine from stomach Small Intestine Mechanical Digestion Bile – emulsifier: fats smaller fat droplets *makes more accessible for pancreatic lipase *enters through bile duct, merges with pancreatic duct *made in the liver (3rd accessory organ) *stored in gall bladder (4th accessory organ) Small Intestine Enzyme Origin Food it Digests Peptidases (proteases) Intestinal walls Proteins Maltase, Lactase, Sucrase Intestinal walls Carbs Pancreatic Amylase Pancreas Starch Trypsin, Chymotrypsin (Proteases) Pancreas Proteins Pancreatic lipase Pancreas Fats Small Intestine Absorption - simplified molecules absorbed villi & microvilli – folds that increase surface area *capillary – in each villus absorbs into bloodstream (diffusion) *lacteals – lymph vessels in villi that absorb fatty acids 4th Stop: The Large Intestine Smaller, thicker intestine that: - reabsorbs H2O & salts - harbors harmless bacteria * break down undigested food * provide us w/ essential vitamins (K) Elimination Feces – undigested food *moves into rectum & expelled Hormones’ Role in Digestion Hormone Function Gastrin Stimulates stomach cells to produce gastric juices Secretin Stimulates pancreas to produce bicarbonate & pancreatic enzymes Cholecystokinin (CCK) Stimulates secretion of pancreatic enzymes & bile