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Explain generally how the digestive system
(mouth, pharynx, esophagus, stomach, small
and large intestines, rectum) converts
macromolecules from food into smaller
molecules that can be used by cells for energy
and for repair and growth.
List the major organs of the digestive system
Relate the structure of each organ with its
function in mechanical digestion
Identify the source of each major digestive
enzyme, and describe the function of the
enzyme
Summarize the process of absorption in both
the small and large intestine
To make energy
using:
food
food
oxygen
O2
ATP
All animals eat other organisms
Herbivores
eat mainly plants
gorillas, cows,
rabbits, snails
Carnivores
eat other animals
sharks, hawks,
spiders, snakes
Omnivores
eat animals & plants
cockroaches, bears, raccoons, humans
humans evolved as hunters, scavengers & gatherers
1. Ingest
taking in food-mouth; pharynx and esophagus
2. Digest
mechanical digestion
breaking up food into smaller pieces
chemical digestion
breaking down food into molecules small enough to be absorbed into cells
enzymes (hydrolysis)
3. Absorb
absorb across cell membrane
diffusion
active transport
4. Eliminate
undigested extracellular material passes out of digestive system
Movement & Control
peristalsis
push food along by rhythmic waves of smooth
muscle contraction in walls of digestive system
sphincters
muscular ring-like valves, regulate the passage of
material between sections of digestive system
Accessory glands
salivary glands, pancreas, liver & gall bladder
secrete digestive juices (enzymes & fluid)
Epiglottis
problem: breathe & swallow through same orifice
flap of cartilage
closes trachea (windpipe) when swallowing
food travels down esophagus
Esophagus
move food along to stomach by peristalsis
Mouth
mechanical digestion
teeth
breaking up food
chemical digestion
saliva
amylase
enzyme digests starch
mucin
slippery protein (mucus)
protects soft lining of digestive system
lubricates food for easier swallowing
buffers
neutralizes acid to prevent tooth decay
anti-bacterial chemicals
kill bacteria that enter mouth with food
mouth
break up food
moisten food
digest starch
kill germs
Food is chewed in the
mouth and forms a
bolus
The bolus travels down
the esophagus-a long
tube- by peristalsis
It then enters the
stomach through a
sphincter
mouth
break up food
moisten food
digest starch
kill germs
Functions
food storage
disinfect food
chemical digestion
pepsin
enzyme breaks down
proteins
secreted as pepsinogen
activated by HCl
But the stomach is made out of protein!
What stops the stomach from digesting itself?
mucus secreted by stomach cells protects
stomach lining
mouth
break up food
moisten food
digest starch
kill germs
stomach
kills germs
store food
break up food
digest proteins
esophagus
cardiac
sphincter
pyloric
sphincter
Doctors used to think
ulcers were caused by
stress
Colonized by
H. pylori
tried to control with
antacids
inflammation of
stomach
Now we know ulcers are
caused by bacterial
infection of stomach
Helicobacter pylori
now cure with antibiotics
H. pylori
Free of
H. pylori
inflammation of
esophagus
Function
major organ of digestion & absorption
chemical digestion
digestive enzymes
absorption through lining
over 6 meters!
small intestine has huge surface area
= 300m2 (~size of tennis court)
Structure
3 sections
duodenum = most digestion
jejunum = absorption of nutrients & water
ileum = absorption of nutrients & water
1st section of small intestines is still digesting
acid food from stomach mixes with digestive juices
from accessory glands:
 pancreas
 liver
 gall bladder
Releases digestive
enzymes to further break
down macromolecules
into smaller ones
Buffers
Help reduce acidity of
chyme from the
stomach-bicarbonate
small intestines
mouth
break up food
moisten food
digest starch
kill germs
pancreas
produces enzymes to
digest proteins & starch
stomach
kills germs
break up food
digest proteins
store food
Helps the digestive system
produce bile
stored in gallbladder until needed
breaks up fats
act like detergents to breakup fats
mouth
break up food
moisten food
digest starch
kill germs
liver
produces bile
- stored in gall bladder
break up fats
pancreas
produces enzymes to
digest proteins & starch
stomach
kills germs
break up food
digest proteins
store food
Absorption through villi & microvilli
finger-like projections
increase surface area for absorption
How is the villi’s
structure related
to it’s function?
Passive transport
fructose
Active (protein pumps) transport
pump amino acids, vitamins & glucose
against concentration gradients across intestinal cell
membranes
allows intestine to absorb much higher proportion
of nutrients in the intestine than would be possible
with passive diffusion
worth the cost of ATP!
mouth
break up food
moisten food
digest starch
kill germs
liver
produces bile
- stored in gall bladder
break up fats
pancreas
produces enzymes to
digest proteins & starch
stomach
kills germs
break up food
digest proteins
store food
small intestines
breakdown all
foods
- proteins
- starch
- fats
- nucleic acids
absorb nutrients
Function
re-absorb water
use ~9 liters of water every
day in digestive juices
> 90% of water reabsorbed
not enough water absorbed
back to body
diarrhea
too much water absorbed
back to body
constipation
Living in the large intestine is a rich
flora of harmless, helpful bacteria
Escherichia coli (E. coli)
a favorite research organism
bacteria produce vitamins
vitamin K; biotin, folic acid & other B vitamins
generate gases
by-product of bacterial
metabolism
methane, hydrogen sulfide
Last section of colon (large intestines)
eliminate feces
undigested materials
extracellular waste
mainly cellulose from plants
roughage or fiber
salts
masses of
bacteria
appendix
mouth
break up food
moisten food
digest starch
kill germs
liver
produces bile
- stored in gall bladder
break up fats
pancreas
produces enzymes to
digest proteins & carbs
stomach
kills germs
break up food
digest proteins
store food
small intestines
breakdown food
- proteins
- starch
- fats
absorb nutrients
large intestines
absorb water
Ingestion: mouth & esophagus
Digestion: stomach, small
intestine
Absorption: small intestine;
large intestine
Elimination: larges intestine,
rectum, anus
Review
1. Name 2 types of digestion
2. What are the 4 processes of the digestive
system?
3. List in order the 5 organs food passes through.
4. List 4 accessory organs
5. Name what organs break down which organic
molecules.
6. How do organic molecules, vitamins and
nutrients get to where they are needed in the
body?