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Physiology for Nutrition, Health and Fitness Does what we Eat, Think, Do really matter? Important Factors in Health 1) Diet (Nutrition) 2) Mentality and Emotions 3) Physical Activity 4) Toxins (Environment) 5) Spirituality Materials for the Body • Carbohydrates • Minerals • Lipids • Vitamins • Proteins • Enzymes Whole Foods • Unrefined, entire original “item”. • All original nutrients remain intact. • Unprocessed, not chemically treated. e.g.: - whole brown rice (),quinoa - organic vegetables and fruit - raw nuts and seeds Refined Foods • Heavily processed from original form. • Most (if not all) original nutrients removed. • Often chemically treated (in processing and for shelf-life). e.g.: - white sugar () - white flour - heavily preserved (packaged) items What is a Carbohydrate? Glucose* = monosaccharide, a simple sugar Lactose* = disaccharide (glucose and galactose) Maltose* = disaccharide (glucose and glucose) Sucrose** = disaccharide (glucose and fructose) Cellulose = polysaccharide (cannot digest) Starch = polysaccharide (many glucose molecules) Simple Refined - candy - white bread - potato chips Complex Whole - fruits - whole grains - vegetables What is Sugar? Glucose - most important sugar in Human Body! Sucrose - highly refined, ‘table sugar’ – Avoid! High Fructose Corn Syrup – Evil!!! “But it tastes so good” Why? Insulin Levels Rollercoaster ride = Diabetes Mellitus Type II Advanced Glycation End-products (AGE’s) Glycoproteins - normal. If blood glucose chronically elevated, it binds to proteins non-enzymatically = AGE’s This is when things start to go wrong! Impaired circulation BKA’s Blindness Diet and the Immune System The Effects of Carbohydrates on the Phagocytic Index Sugar suppresses Immune System! * Rat tooth enamel study Many pathways in the body elevate blood glucose but only one lowers it. Insulin Why only one way to lower blood glucose??? Far more Sugar in our Diet now! e.g., in 1999 the average American consumed 150lbs of sugar/year. Why? Cultural? Social? Conditioning? Television, Movies, Advertisements Taste Test (Montague, 2005) A B 50% - 50% split! Coke 85% chose coke! Pepsi 50% - 50% split! Researcher’s Comment “There are visual images and marketing messages that have insinuated themselves into the nervous system of humans who consume the drink. It is possible that cultural messages perturb taste sensation.” All Fats are Not Equal! Omega-3- and 6-Fatty Acids Cholesterol (LDL’s and HDL’s) Hydrogenated Vegetable Oils Trans Fats and Acrylamide *Dr. Ancel Keys (1958) Ischemic Heart Disease Unsaturated Oils vs. Saturated Fats Polyunsaturated Fats – e.g., canola, soybean, safflower, corn - easily become rancid when exposed to oxygen and produce free radicals in the body. *Olive oil – Still good; best if not heated! Virgin Coconut Oil - a saturated fat with medium chain Fatty Acids (MCFA) extremely heat stable and very beneficial for human physiology. Saint-Onge and Jones (2003) Eating fat makes you fat and increases your risk of cardiovascular disease - Right? Comparison of Molecules (120Kcal each) Glucose 2 slices of bread. Sucrose 1 glass of orange juice. Ethanol 1 shot of bourbon. *Dr. Robert Lustig’s “Sugar: The Bitter Truth” Glucose Sucrose Ethanol 1 glass of orange juice 1 shot of bourbon Starch => glucose 60 kcal glucose + 60 kcal fructose CNS Depressant ~96 kcal used by all cells in body ~48 kcal used by all cells in body ~24 kcal used by all cells in body ~24 kcal hits Liver for Metabolism ~72 kcal hits Liver for Metabolism ~96 kcal hits Liver for Metabolism 2 slices of bread Glucose-6-℗ Makes Glycogen ~0.5 kcal used for de novo Lipogenesis ↑ Insulin Inhibits Ghrelin Glucose-6-℗ ↑ Aldehydes ↑ Uric acid ↑ VLDL + ↓NO = ↑BP ↑ de novo Lipogenesis No effect on Ghrelin ↑ Aldehydes ↑ Acetate, ↑ Citrate ↑ VLDL ↑ de novo Lipogenesis Dislipidemia ↑ Insulin resistance When blood Glucose is high Insulin is released to make blood Glucose lower (normal) Cells in your body up-take the glucose When blood Glucose is low Glucagon is released to make blood Glucose higher (normal) Liver is key site: Hepatocytes liberate Glucose stores (glycogen) and use fats & proteins to make more glucose *Glycogenolysis * Glycemic Index and Diabetes Mellitus Diabetic Normal How much Protein? Metabolic Typing 1. High Protein. 2. High Carbohydrate. 3. Mixed. High in Protein a) Meat growth hormone injected, antibiotic loaded, corn fed, poorly treated, sick animals. b) Soy trypsin inhibitors, goitrogens, phytic acid, phytoestrogens, haemagglutinin, GM. c) Eggs Find organic eggs! Nutrient rich! d) Quinoa Complete protein, higher protein content than soy. One of the best foods to eat to control blood glucose is Fats - the right fats! Acetyl CoA Hydroxymethyl Glutaric Acid (HMG-CoA) Statin = HMG-CoA reductase inhibitors Mevolaonate Mevolaonate Pyrophosphate Isopentenyl Pyrophosphate Geranyl Pyrophosphate Famesyl Pyrophosphate Squalene Ubiquinone (CoQ10) Cholesterol Dolichol Cholesterol Vitamin D Cortisone Glucocorticoids Mineralcorticoids Steroid Hormones (testosterone, estrogen, progesterone) Bile Salts … = Cholesterol Good! There must be a BETTER food structure that this Pyramid? Why Organic? 1. No growth stimulants, no antibiotics, no artificial fertilizers. 1. No pesticides, irradiation, preservatives, additives, artificial colors or flavors. 3. No Genetically Modified Organisms (GMOs). 4. Primarily Locally Grown, Seasonal food. 5. Higher nutrient and mineral values ( taste). DMT β- Endorphins Some Facts: 65% of Americans are overweight. 27% are clinically obese. (17% of kids ages 6 to 19) 60% of Americans do not exercise. 3 Worst Foods? 1. 2. 3. #3 Acrylamide ↑ starch ↑ glycemic index! ↑ Trans Fats GM Potatoes Zero Nutrients * Tertiary Butylhydroquinone (TBHQ) #2 Regular Diet Average American consumes 54 gallons/year #1 Acrylamide Sugar ↑ ↑ glycemic index! GM Bleach White Flour 30-40% Trans Fat 200-300 Calories Suggestions: Avoid certain “foods”! - No, not even in moderation! - Better Alternatives?: What about artificial additives and flavors? Question why they are added. Examine what their effects might be. • MonoSodiumGlutamate (MSG) ‘flavoring’. • Aspartame artificial ‘sweeter’ (Sucralose) Excitotoxins (“Excitotoxins: The Taste that Kills” by Dr. Russell Blaylock, 1995) Substances when ingested in high quantities interfere with nervous transmission. e.g., interfere with the excitatory neurotransmitters Glutamate and Aspartate. Why is MSG bad for you?!? Interferes with actions of the Hypothalamus in your brain. Satiety Center Inhibited by MSG “Truth in Labeling” organization lists the Hidden names for MSG Foods always contain MSG when these words are on the label: MSG Gelatin Calcium Caseinate Hydrolyzed Monosodiu Textured Vegetable m glutamate Protein Protein (HVP) Monopotassi Hydrolyzed um Plant Protein Yeast Extract glutamate (HPP) Autolyzed Yeast food or Glutamate Plant Protein nutrient Glutamic Sodium Autolyzed Acid Caseinate Yeast Foods made with the following products often contain MSG. Malted Barley (flavor) Flavors, Flavoring, Reaction Flavors Modified food starch Barley Malt Fermented "anything" Rice syrup or brown rice syrup Malt Extract or Flavoring Natural Chicken, Beef, or Pork, Flavoring "Seasonings” Lipolyzed butter fat Maltodextrin Soy Sauce or Extract "Low" or "No Fat" items Soy Protein, Stock Caramel Flavoring (coloring) Corn syrup, corn syrup solids Bouillon, Protease Soy Protein Isolate or Concentrate Citric Acid (from corn), Cornstarch Broth, Pectin Wheat, rice, or oat protein Milk Powder Carrageenan Flowing Agents Dry Milk Solids Anything enriched or vitamin enriched Protein fortified "anything" Protein Fortified Milk Whey Protein or Whey Enzyme modified "anythng" Gums, Annatto Whey Protein Isolate or Concentrate Ultra-pasteurized "anything" Spice or Spices Protease enzymes Dough Conditioners Yeast Nutrients Girl Scout Cookie Label Lets Examine Sodas Contains lots of sugar Contains no sugar ? Aspartame - An Intense Source of Excitotoxins • Made from phenylalanine and aspartate. • Accounts for ~ 70% of all complaints to FDA. • Breaks down at room temp into toxic and dangerous ingredients: 1. DKP (di-ketopiperazine). When ingested, converts to a near duplicate of a powerful brain tumor causing agent. 2. Formaldehyde - embalming fluid. 3. Methanol - extremely dangerous alcohol, causes blindness. Dangerous Ingredients in Diet Coke Ingredients Purpose Adverse Effects Aspartame Sweetener Breaks down to its neurotoxic components phenylalanine, aspartic acid and methyl alcohol. FDA reports consumption associated with headaches, dizziness, loss of balance, mood swings, nausea, memory loss, muscle weakness, blurred vision, fatigue, weakness, skin rashes, joint and musculoskeletal pain. Also linked rare tumors known as gliomas and lymphomas. Acesulfame K Sweetener Causes cancer in animals. Breaks down to Acetoacetamide, shown to affect the thyroid gland in rats, rabbits, and dogs. Use with aspartame to cover its bitter taste, however, there are no studies to show if the combination is safe or whether it produces other toxic by-products. Phosphoric Acid Acidifier Erodes tooth enamel; leaches calcium from bones. High soda intake children suffer from osteoporosis. Citric Acid Preservative, Acidifier Harsh on tooth enamel, but when mixed with potassium or sodium benzoate during storage (esply at raised temperatures), can form benzene, a known carcinogen. More Dangerous Ingredients in Diet Coke Ingredients Purpose Adverse Effects Caffeine Flavoring A CNS stimulant, highly addictive, diuretic; can provoke mood changes, lethargy and headache. Ingestion of high levels can cause miscarriage, peptic ulcers and heart ailments. Children consuming caffeine have higher incidences of illness, headaches, sleep problems and iron depletion. Sodium Benzoate (E211) Preservatives In acidic solutions (e.g., sodas), benzoates can break down into benzene. Surveys show levels in soft drinks up to 40 times higher than recognized ‘safe’ doses. Sulphite Ammonia Caramel (E150d) Coloring Made by heating sugar, ammonia and sulphites. Ammonia is toxic and caramels made by an ammonia process may damage genes, slow growth, cause enlargement of the intestines and kidneys and destroy vitamin B. This coloring has never been fully evaluated for its potential toxicity. “Artificial sweeteners tied to obesity, Type 2 diabetes” Feb 14th, 2013 Sugar Aspartame Environmental Toxins • Not just in what you eat! • Cosmetics, Personal Hygiene, Perfumes. • House Cleaning Agents and Solvents. Harmful Ingredients in Cosmetics! • Parabens – widely used in skin-care products. Mimic estrogen, encourages growth of human breast tumors. • Phenol Carbolic Acid - found in many lotions and skin creams. Can cause circulatory collapse, paralysis, convulsions, respiratory failure. • Methylisothiazoline (MIT) – extensively used in shampoos. Causes neurological damage (National Institute of Health). More • Sodium Lauryl Sulfate - the 'foam-up' of soaps, shampoos, detergents, toothpastes. Breaks skin’s moisture barrier, can become a “nitrosamine”. • Toluene - in most synthetic fragrances. Linked to anemia, ↓ blood cell count, liver/kidney damage. • Propylene Glycol - main ingredient in antifreeze and used in hydraulic fluids. Dermatitis; kidney/ liver abnormalities The Information is Out There 1. Question Everything – Don’t blindly accept. 2. Empower yourself by knowing things. Allows us to make well-informed decisions “Our lives begin to end the moment we become silent about the things that matter” Martin Luther King Jr. Our Bodies are amazing, Let’s look after them! The Vetruvian Man expressed the Canon of Proportions. Education • The knowledge or skill obtained or developed by a learning process. Edification • Intellectual, moral, or spiritual improvement; enlightenment.