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G.I. Disorders Lower G.I. and accessory organs Irritable Bowel Syndrome Approximately 5 million people in the U.S. suffer with the syndrome Also known as: – Colitis Does not always include inflammation – Spastic colon Does not always occur in the Colon – Not to be confused with Ulcerative Colitis Irritable Bowel Syndrome Characterized by: – Pain (duration > 3 months) Symptoms – Diarrhea, constipation or alternating episodes of both – Flatulence, bloating, – Indigestion, belching, heartburn, nausea – Mucus in the stool Irritable Bowel Syndrome Medical Nutrition Therapy – Elemental diet, for persons with acute IBS – Low fat Diet, with liberal fruits and veggies Soluble fiber – Avoid milk (lactose intolerance common) – Liberal lactose free liquids – Avoid spicy foods – Avoid gas-forming foods – Avoid caffeine, alcohol, sorbitol Client Education Vitamin B-complex supplement may be necessary Encourage regular bowel evacuation Stress and coping mechanisms Regular exercise Food diaries may help identify food sensitivities Products that reduce intestinal gas (Bean-O) Diverticular Disease Diverticula – the presence of outpouchings in the intestinal wall – Diverticulum Diverticulitis – inflammation of diverticula Diverticulosis – the presence of diverticula Diverticular Disease ©2001 Brooks/Cole, a division of Thomson Learning, Inc. Thomson Learning™ is a trademark used herein under license. Medical Nutrition therapy Diverticulitis (Inflamed state) Bowel rest – NPO (nil per os) Clear liquids Progress to Soft, Low fat diet No excess spices or fiber Gradually progress to normal fiber intake as inflammation decreases Medical Nutrition therapy Diverticulosis (Convalescent state) High fiber - >30grams per day desirable – Start with small amount and increase gradually – Add whole grains, raw fruits and vegetables Increase Low fat fluid intake Medical Nutrition therapy In both conditions, AVOID: Small seeds (strawberries, poppy) Nuts, chunky peanut butter Popcorn Corn Fibrous vegetables Ulcerative Colitis Inflammatory bowel disease Symptoms: – Diarrhea (resulting in malabsorption) – Rectal bleeding (resulting in anemia) – Cramping, abdominal pain – Anorexia, weight loss Medical Nutrition therapy Dietary disease interventions do not lessen – Low fiber – Lactose free – Vitamin and mineral supplementation Regional Enteritis (Crohn’s) Inflammation and ulceration of the G.I. tract. Nutrition consequences – Protein malnutrition hypoalbuminemia – Vitamin deficiencies Vitamin B12, Folate, C and fat solubles – Mineral deficiencies Calcium, Magnesium, Zinc, Iron – Anemia Medical Nutrition therapy High kcal, High protein, (1-1.5g/kg) Fat restricted (if steatorrhea is present) Low fiber Vitamin and mineral supplementation Avoid foods not well tolerated (i.e. lactose) Small, frequent meals recommended Celiac Disease Also known as Celiac Sprue Inflammatory condition of the G.I. tract that affects the small intestines. Malabsorption due to a sensitivity to Gliadin Gliadin = part of the protein Gluten found in: wheat, buckwheat, Rye, barley Oats (can usually be taken in small amounts) Celiac Disease Consequences Protein malnutrition (low serum protein levels) Anemia – iron, folate and Vit B12 deficiency Steatorrhea, diarrhea (resulting in weight loss) Calcium deficiency (resulting in bone pain) Vitamin and mineral deficiencies (fat soluble vitamins lost with steatorrhea) Medical Nutrition therapy Gliadin-free/ gluten restricted diet – No wheat, buckwheat, rye,barley – Small amount of oats (may be contaminated with wheat during processing) May have: corn, rice, tapioca, potato, arrowroot, cassava (yuca) gluten-free flour Lactose restricted Vitamin and mineral supplementation Accessory Organs Pancreatitis Inflammation of the Pancreas Acute – due to organ autodigestion - Usually as a result of duct obstruction - Enzymes become activated in duct instead of duodenum Alcohol abuse Gallstones (~45% of all cases) Acute Pancreatitis Symptoms of Acute Pancreatitis Sudden, severe abdominal pain – May be constant and disabling Nausea, vomiting Diarrhea Approximately pancreatitis 25% develop chronic Medical Nutrition therapy NPO with IV feedings ~ 48 hours Jejunostomy feedings if longer Clear liquid progress to Low fat diet Provide pancreatic enzyme replacement Small frequent meals No alcohol, caffeine Chronic Pancreatitis Fibrotic, necrotic disease where cells suffer permanent damage. Decreased enzyme production Nausea, vomiting, abdominal pain Most common cause is alcohol abuse (~70%) Other causes: pancreatic cancer, Cystic Fibrosis Medical Nutrition therapy High calorie, semi-elemental tube feeding Low fat, high calorie, moderate protein Low fiber Six small meals No alcohol, caffeine or gastric stimulants Vitamin and mineral supplementation Cystic Fibrosis Consequences Pancreatic insufficiency (80-90%) – May require enzyme replacement, insulin Chronic lung disease – Lung infections – major cause of death Growth retardation (85%) Decreased bone density Abnormally high electrolytes in sweat Medical Nutrition therapy High kcal, high protein – 20 – 50% above normal needs Pancreatic enzymes – To control steatorrhea Multivitamin supplementation Liberal salt use Encourage fluids Medical Nutrition therapy When body weight falls below 85% std, alternate feedings are indicated. Infant feeding: – Enzyme replacement with breast feeding – Up to ¼ tsp salt daily given to replace losses Liver: Hepatitis Definition: Inflammation of the Liver 5 types Hepatitis A associated with food/water contamination – highly contagious. Hepatitis Symptoms Jaundice - Dark urine - Elevated liver enzymes - Tender, enlarged liver Hepatitis is mainly acute, but sometimes chronic – May lead to cancer, liver failure, hepatic coma, death - Medical Nutrition Therapy Regular diet High protein, high kcal (if malnourished) Small, frequent feedings – Anorexia, nausea is common Nutritional supplement (Ensure, Boost) Cirrhosis Definition: Chronic liver failure where scar tissue replace liver cells and there is a permanent loss of function. Causes: Alcohol abuse Biliary tract obstruction Infection Consequence of Cirrhosis Portal hypertension Esophageal varices Ascites Elevated blood Ammonia levels Hepatic Coma Changes in judgment, mood, personality Sweet, musky or pungent (fecal) odor Flapping tremor of outstretched hand Medical Nutrition Therapy Energy: adequate carbohydrate and fat to spare protein (35-45kcal/kg BW) Protein (1.0 – 1.5 gm/kg BW) – Enough to regenerate cells, but not increase ammonia – Impending coma (40 – 60 gm/day) – Coma Vegetable protein and Branch Chain Amino Acid Medical Nutrition Therapy Drug Therapy Sodium (2 grams) – To limit growth of intestinal bacteria – To control ascites Fluids (1.0 – 1.5 liters/ day) Antibiotics Laxatives – to decrease transit time – Restricted to control Diuretics ascites – To reduce fluid Vitamin and mineral retention Cholelithiasis Gallstones: solid masses that form in the gallbladder from bile Bile: fat emulsifier produced in the liver and stored in the gallbladder Gallstones are: – Cholesterol stones – Pigment stones Risk Factors Body weight (obesity) Gender (female) Age (~40 yrs) Ethnicity Type II diabetes Short bowel syndrome, gastric bypass Certain medications Medical Nutrition Therapy Low fat – Weight reduction if appropriate High fiber – Soluble fibers bind bile acids Avoid gas formers – Prevent distention Water-based fat soluble vitamins Renal Diseases: Nephrotic Syndrome Definition: Cluster of symptoms which result in protein in the urine (albuminuria) Consequences: – Protein calorie malnutrition – Anemia – Infection – Atherosclerosis For unknown reasons, blood lipid levels rise Medical Nutrition Therapy Adequate non-protein calories Normal protein intake (0.8 – 1.0 gm/kg) Low saturated fat/ low cholesterol Sodium restriction (~2 grams) Renal Failure Definition: Loss of the kidney’s ability to function May be acute or chronic Consequences: – Uremia (azotemia) – Electrolyte imbalance (Hyperkalemia) – Changes in fluid balance Medical Nutrition therapy Consider: – Energy needs (non-protein kcalories) – Protein restriction Depending on kidney function – Electrolyte restriction` Sodium, potassium, phosphorus – Fluid restriction Monitor intake and output – Supplements Calcium, folate, Vitamin B6, Vitamin D Renal Calculi (kidney stones) Calcium stones (>75%) – Causes: Hypercalciuria (idiopathic) – Immobilization – hyperoxaluria Medical Nutrition Therapy – Calcium management – Increased fluids – Limit oxalate intake Renal Calculi (kidney stones) Uric Acid Stones – Common in gout Medical Nutrition Therapy – Low Purine diet – Increase fluids Cystine stones – Genetically linked Medical Nutrition Therapy – Low Methionine diet – Increased fluids